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Connector-enabled integration of Golden Gate Assembly and yeast recombination for streamlined multigene pathway construction in the biofoundry workflow.

Seong MJ, Kim H, Lee H, Kim H, Lee SG, Lee MJ, Jun JS, Hong S, Kim TH, Kim SK, Shin J, Lee DH
Trends Biotechnol. 2026 Jan 14:S0167-7799(25)00502-5. doi: 10.1016/j.tibtech.2025.12.004. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
254020Modified pYTK075A part plasmid designed to use the yeast selective marker (LEU2 gene) as a Level 1 TU fragment.
254021Modified pYTK048It was constructed by reversing the orientation of the BsaI sites in the original pYTK048 and is used for the construction of connectors.
254023pConnector_L1-R2A plasmid containing the L1-R2 connector.
254024pConnector_L2-R3A plasmid containing the L2-R3 connector.
254025pConnector_L2-REA plasmid containing the L2-RE connector.
254026pConnector_L3-R4A plasmid containing the L3-R4 connector.
254027pConnector_L4-R5A plasmid containing the L4-R5 connector.
254029pConnector_L5-R6A plasmid containing the L5-R6 connector.
254031pConnector_L7-R8A plasmid containing the L7-R8 connector.
254033pConnector_L8-REA plasmid containing the L8-RE connector.

Antibodies from Article