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Sequence-encoded differences in the conformational ensembles of CITED transcriptional activation domains impact coactivator binding.

Do TU, Kraft EJ, Chappell GF, Parnham S, Berlow RB
bioRxiv [Preprint]. 2026 Jan 21:2026.01.20.700670. doi: 10.64898/2026.01.20.700670. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
254286HisGB1-CITED1(146-193) + CBP TAZ1(340-439)Bacterial coexpression of human CITED1 CTAD with CBP TAZ1
254287HisGB1-CITED2(216-270) + CBP TAZ1(340-439)Bacterial coexpression of human CITED2 CTAD with CBP TAZ1
254288HisGB1-CITED4(130-184) + CBP TAZ1(340-439)Bacterial coexpression of human CITED4 CTAD with CBP TAZ1
254289Avi-TAZ1Bacterial expression of His- and Avi-tagged CBP TAZ1

Antibodies from Article