AKT is necessary for neuronal hypertrophy and epilepsy caused by Pten knockout.
Prina ML, Goyette AR, Abdulkareem AF, Tariq K, Burgess N, Su J, Wang W, Li M, Drucker LL, Seo HH, Desmet NM, Overstreet-Wadiche L, Shafit-Zagardo B, Weston MC, Luikart BW
Brain. 2026 Mar 9:awag098. doi: 10.1093/brain/awag098.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 189008 | pRubiG-T2A-AKT3-T2A-Cre | Retroviral vector with a ubiquitin promoter expressing GFP, human AKT3 transcript variant 1 ORF and Cre recombinase, separated by T2A motifs |
| 189011 | pRubiG-T2A-AKT1-T2A-Cre | Retroviral vector with a ubiquitin promoter expressing GFP, human AKT1 ORF, and Cre recombinase, separated by T2A motifs. |