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A human-cell recombinant prethrombin-2 platform producing thrombin with enhanced fibrinogen processing for in vitro applications.

Swaid H, Mendes SR, Fuentes-Prior P, Rodriguez-Banqueri A, Gomis-Ruth FX
Thromb Res. 2026 Oct 5;266:109863. doi: 10.1016/j.thromres.2026.109863. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
255428Sp6-PE2 Expresses recombinant human Pre-thrombin 2 (PE2) starting at T272 using Expi293F cells.
255429Sp6-rpEcaExpresses recombinant Pro Ecarin using Expi293F cells.
255520Sp6-PE2-S525AExpresses recombinant human Pre-thrombin 2 (PE2) starting at T272 with the mutation S525A using Expi293F cells.

Antibodies from Article