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Le Cong Lab: Surfaceome CRISPR activation screening uncovers ligands regulating tumor sensitivity to NK cell killing

Unpublished

Plasmids from Article

ID Plasmid Purpose
255456pLV EF1a Fluc2 2A GFP 2A BSDExpresses firefly luciferase, eGFP, and blasticidin deaminase from a lentiviral vector
255457AAVS1 BSD EF1a Fluc2 2A GFPAAVS1 knock-in construct that expresses firefly luciferase, eGFP, and blasticidin deaminase
255458pLV EF1a dCas9VP64 2A EGFP 2A BSDExpresses dCas9VP64, eGFP, and blasticidin
255459pLV Ef1a 2A PuroR 2A BFPAllows for facile cloning of an insert cDNA upstream of Puromycin resistance and BFP markers
255460pLV EF1a 2A HygroR 2A mKateAllows for facile cloning of an insert cDNA upstream of hygromycin resistance and mKate markers
255461lentiCRISPRi v3Expresses sgRNA2.1 cassette, dCas9-Zim3, and puromycin resistance
255462pLV EFS PCP-p65-HSF1 2A mcherry2 2A HygRExpresses SAM components PCP-p65-HSF1, mcherry2, and hygromycin resistance
255463pLV U6 sgRNA2.0 pp7 EFS Puro 2A.BFPExpresses Puro and BFP and has an sgRNA2.0 scaffold for insertion of CRISPR activation gRNAs
255499eSpCas9(1.1)-T2A-GFP - GlntRNAExpresses eSpCas9(1.1) with GFP and a GlntRNA promoter for gRNA expression

Antibodies from Article