SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis.
Liu S, Gad M, Li C, Cho K, Liu Y, Wangdu K, Belay V, Millet A, Kojima H, Sanford H, Wolk M, Urnavicius L, Fedorova M, Patti GJ, Vinogradova EV, Hite RK, Birsoy K
Nat Cell Biol. 2026 Apr 17. doi: 10.1038/s41556-026-01922-y.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 255987 | PMXS-EMC3-mScarlet-3xHA-IRES-bleomycin | PMXS construct expressing EMC3-mScarlet-3xHA with an IRES-bleomycin cassette for ER-IP |
| 255988 | PMXS-EMC3-mScarlet-3xMYC-IRES-bleomycin | PMXS construct expressing EMC3-mScarlet-3xMYC with an IRES-bleomycin cassette for use as an IP control |
| 255989 | PMXS-EMC3-mScarlet-3xHA-IRES-blasticidin | PMXS construct expressing EMC3-mScarlet-3xHA with an IRES-blasticidin cassette for ER-IP |
| 255990 | PMXS-EMC3-mScarlet-3xMYC-IRES-blasticidin | PMXS construct expressing EMC3-mScarlet-3xMYC with an IRES-blasticidin cassette for use as an IP control. |
| 255991 | PMXS-OST4-mScarlet-3xHA-IRES-blasticidin | PMXS construct expressing OST4-mScarlet-3xHA with an IRES-blasticidin cassette for ER-IP |
| 255992 | PMXS-OST4-mScarlet-3xMYC-IRES-blasticidin | PMXS construct expressing OST4-mScarlet-3xMYC with an IRES-blasticidin cassette for use as an IP control. |
| 257599 | pMXS_IRES_GFP_FLAG-33A1 | Expression of FLAG-tagged human SLC33A1 with GFP reporter |
| 257600 | pLJC6-FLAG-SLC33A1-Blast | Lentiviral expression of FLAG-tagged human SLC33A1 |
| 257601 | pLJC6-FLAG-SLC33A1-Y225A-Blast | Expression of FLAG-tagged human SLC33A1 Y225A mutant |
| 257602 | pLJC6-FLAG-SLC33A1-N229A-Blast | Expression of FLAG-tagged human SLC33A1 N229A mutant |
| 257603 | pLJC6-FLAG-SLC33A1-Q356A-Blast | Expression of FLAG-tagged human SLC33A1 Q356A mutant |
| 257604 | pLJC6-FLAG-SLC33A1-Y390A-Blast | Expression of FLAG-tagged human SLC33A1 Y390A mutant |
| 257605 | pLJC6-FLAG-SLC33A1-Y418A-Blast | Expression of FLAG-tagged human SLC33A1 Y418A mutant |
| 257606 | pLJC6-FLAG-SLC33A1-Q422A-Blast | Expression of FLAG-tagged human SLC33A1 Q422A mutant |
| 257607 | PCW57.1-ER-GshF-GFP | Doxycycline-inducible expression of ER-targeted GshF-GFP |
| 257609 | lentiCRISPR-v2_sg_SLC33A1 | CRISPR knockout of human SLC33A1 |
| 257610 | lentiCRISPR-v2_sg_Slc33a1 | CRISPR knockout of mouse Slc33a1 |
| 257611 | lentiCRISPR-v2_sg2_SYVN1 | CRISPR knockout of SYVN1 using sgRNA 2 |
| 257612 | lentiCRISPR-v2_sg4_SYVN1 | CRISPR knockout of SYVN1 using sgRNA 4 |
| 257613 | lentiCRISPR-v2_sg1_Ero1a | CRISPR knockout of Ero1a using sgRNA 1 |
| 257614 | lentiCRISPR-v2_sg2_Ero1a | CRISPR knockout of Ero1a using sgRNA 2 |