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Structural plasticity drives convergent evolution and functional diversification of GNAT polyamine acetyltransferases.

Roca-Martinez J, Leiva Martel HN, Yin J, Do HD, Le VTB, Bordin N, Rauer C, Orengo C, Kuhn ML
Structure. 2026 Aug 24:S0969-2126(26)00246-7. doi: 10.1016/j.str.2026.07.015. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
257259pMCSG53_ A0A085HNR3_UCL01Bacterial expression of acetyltransferase from Leminorella grimontii
257260pMCSG53_ A0A0D3EG88_UCL02Bacterial expression of acetyltransferase from Brassica oleracea
257261pMCSG53_ A0A0L9TB63_UCL03Bacterial expression of N-alpha-acetyltransferase 60 from Phaseolus angularis
257262pMCSG53_ A0A0L9UV05_UCL04Bacterial expression of acetyltransferase from Phaseolus angularis
257263pMCSG53_ A0A0M8UFT0_UCL05Bacterial expression of acetyltransferase from Streptomyces sp.
257264pMCSG53_ A0A0U2XFL6_UCL06Bacterial expression of GNAT family acetyltransferase from Enterococcus rotai
257265pMCSG53_ A0A199V078_UCL07Bacterial expression of N-alpha-acetyltransferase 60 from Ananas comosus
257266pMCSG53_ A0A1C3SJK7_UCL08Bacterial expression of ywnH from Bacillus glycinifermentans
257267pMCSG53_ A0A1E5L1F7_UCL09Bacterial expression of acetyltransferase from Enterococcus rivorum
257268pMCSG53_ A0A1F8V1D7_UCL10Bacterial expression of acetyltransferase from Clostridiales bacterium
257269pMCSG53_ A0A1G0SZI3_UCL11Bacterial expression of acetyltransferase from Ignavibacteria bacterium
257270pMCSG53_ A0A1G1FE98_UCL12Bacterial expression of acetyltransferase from Nitrospirae bacterium
257271pMCSG53_ A0A1G6VBA2_UCL13Bacterial expression of acetyltransferase from Paenibacillus sp.
257272pMCSG53_ A0A1G7IVK0_UCL14Bacterial expression of Spermine/spermidine N-acetyltransferase from Fontibacillus panacisegetis
257273pMCSG53_ A0A1J0A8H1_UCL15Bacterial expression of acetyltransferase from Vagococcus teuberi
257274pMCSG53_ A0A1J6ILB1_UCL16Bacterial expression of acetyltransferase from Nicotiana attenuata
257275pMCSG53_ A0A1L3MNT0_UCL17Bacterial expression of acetyltransferase from Bacillus weihaiensis
257276pMCSG53_ A0A1Q3BRB5_UCL18Bacterial expression of acetyltransferase from Cephalotus follicularis
257277pMCSG53_ A0A1Q5GKK1_UCL19Bacterial expression of acetyltransferase from Streptomyces sp.
257278pMCSG53_ A0A1S3UCM2_UCL20Bacterial expression of N-alpha-acetyltransferase 50 from Vigna radiata
257279pMCSG53_ A0A1S3VLI5_UCL21Bacterial expression of N-alpha-acetyltransferase 60 from Vigna radiata
257280pMCSG53_ A0A1S3VLY7_UCL22Bacterial expression of N-alpha-acetyltransferase 60 from Vigna radiata
257281pMCSG53_ A0A1S3Y9Z8_UCL23Bacterial expression of N-alpha-acetyltransferase 50 from Nicotiana tabacum
257282pMCSG53_ A0A1S3ZY97_UCL24Bacterial expression of N-alpha-acetyltransferase 50-like isoform X2 from Nicotiana tabacum
257283pMCSG53_ A0A1S7HXP5_UCL25Bacterial expression of acetyltransferase from Zygosaccharomyces parabailii
257284pMCSG53_ A0A1Y6FS14_UCL26Bacterial expression of acetyltransferase from Bacillus sp.
257285pMCSG53_ A0A212KWQ2_UCL27Bacterial expression of acetyltransferase from Chlamydiales bacterium
257286pMCSG53_ A0A268AB52_UCL28Bacterial expression of GNAT family N-acetyltransferase from Terribacillus saccharophilus
257287pMCSG53_ A0A2I4FT10_UCL29Bacterial expression of acetyltransferase from Juglans regia
257288pMCSG53_ A0A2N0GQA0_UCL30Bacterial expression of acetyltransferase from Streptomyces sp.
257289pMCSG53_ A0A3D4XIA9_UCL31Bacterial expression of acetyltransferase from Rikenellaceae bacterium
257290pMCSG53_ A0A3D5S416_UCL32Bacterial expression of acetyltransferase from Cytophagales bacterium
257291pMCSG53_ A0A3P3R6T4_UCL33Bacterial expression of acetyltransferase from Halocatena pleomorpha
257292pMCSG53_ A0A3Q7HP17_UCL34Bacterial expression of acetyltransferase from Solanum lycopersicum
257293pMCSG53_ A0A3R9W1J9_UCL35Bacterial expression of acetyltransferase from Streptomyces sp.
257294pMCSG53_ A0A429SS33_UCL36Bacterial expression of acetyltransferase from Streptomyces sp.
257295pMCSG53_ A0A429TDM0_UCL37Bacterial expression of acetyltransferase from Streptomyces sp.
257296pMCSG53_ A8MFP3_UCL38Bacterial expression of GCN5-related N-acetyltransferase from Alkaliphilus oremlandii
257297pMCSG53_ C5DF28_UCL39Bacterial expression of KLTH0D11748p from Lachancea thermotolerans
257298pMCSG53_ D2RVP6_UCL40Bacterial expression of GCN5-related N-acetyltransferase from Haloterrigena turkmenica
257299pMCSG53_ D5U1D2_UCL41Bacterial expression of acetyltransferase from Thermosphaera aggregans
257300pMCSG53_ E9CQ72_UCL42Bacterial expression of acyltransferase ypeA from Serratia symbiotica
257301pMCSG53_ F8KV13_UCL43Bacterial expression of acetyltransferase from Parachlamydia acanthamoebae
257302pMCSG53_ K9F3F4_UCL44Bacterial expression of acetyltransferase from Leptolyngbya sp.
257303pMCSG53_ M4CXM2_UCL45Bacterial expression of acetyltransferase from Brassica campestris
257304pMCSG53_ M5XZR8_UCL46Bacterial expression of acetyltransferase from Prunus persica
257305pMCSG53_ M7T6B1_UCL47Bacterial expression of acetyltransferase from Thermoplasmatales archaeon
257306pMCSG53_ P21673_UCL48/hSSAT1Bacterial expression of human SSAT1
257307pMCSG53_ Q1QEE3_UCL49Bacterial expression of GCN5-related N-acetyltransferase from Psychrobacter cryohalolentis
257308pMCSG53_ R0GXS5_UCL50Bacterial expression of acetyltransferase from Capsella rubella
257309pMCSG53_ S4YTM0_UCL51Bacterial expression of acetyltransferase from Psychrobacter sp.
257310pMCSG53_ V6S4E7_UCL52Bacterial expression of Phosphinothricin acetyltransferase from Flavobacterium cauense
257311pMCSG53_ V7B9N1_UCL53Bacterial expression of acetyltransferase from Phaseolus vulgaris
257312pMCSG53_ V7CI87_UCL54Bacterial expression of N-alpha-acetyltransferase 60 from Phaseolus vulgaris
257313pMCSG53_ W9RJ30_UCL55Bacterial expression of N-alpha-acetyltransferase 50 from Morus notabilis
257314pMCSG7_ Q9KL03_UCL56/VcSpeGBacterial expression of VcSpeG from Vibrio cholerae
257315pMCSG53_ Q836M4_99010Bacterial expression of Spermine/spermidine acetyltransferase, putative from Enterococcus faecalis
257316pMCSG53_ Q9K330_99016Bacterial expression of acetyltransferase from Vibrio cholerae
257317pMCSG53_ Q18B76_99020Bacterial expression of bltD from Clostridioides difficile
257318pMCSG53_ A0A173UZS7_99021Bacterial expression of bltD from Blautia hydrogenotrophica
257319pMCSG53_ A0A1B1B173_99022Bacterial expression of acetyltransferase from Streptomyces griseochromogenes
257320pMCSG53_ P96579_99023Bacterial expression of YdaF from Bacillus subtilis
257321pMCSG53_ A0A0H2ZAY1_99025Bacterial expression of acetyltransferase from Pseudomonas aeruginosa
257322pMCSG53_ A0A1B1B4L5_99026Bacterial expression of acetyltransferase from Streptomyces griseochromogenes
257323pMCSG53_ Q9RU60_99027Bacterial expression of acetyltransferase from Deinococcus radiodurans
257324pMCSG53_ P39909_99029Bacterial expression of bltD from Bacillus subtilis
257325pMCSG53_ Q9I640_PA0478Bacterial expression of acetyltransferase from Pseudomonas aeruginosa
257326pMCSG53_ Q9I3W7_PA1377Bacterial expression of acetyltransferase from Pseudomonas aeruginosa
257327pMCSG53_ Q9I3P0_PA1472Bacterial expression of acetyltransferase from Pseudomonas aeruginosa
257328pMCSG53_ Q9HWL5_PA4166Bacterial expression of acetyltransferase from Pseudomonas aeruginosa

Antibodies from Article