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Talin controls the spatial distribution of vinculin tension in focal adhesions

Kallem T, Guo Y, Reynolds MK, Ball NJ, Athale M, Baker KB, Mykuliak VV, Ek F, Aldaz-Casanova S, Turkki P, Hytönen VP, Brown NH, Hoffman BD, Yan J, Goult BT
bioRxiv 2026.05.07.722930 (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
245893mVD1_WTBacterial expression of WT mVD1 (2-258)
245894mVD1_A50IBacterial expression of WT mVD1 (2-258) A50I
245895mVD1_I12KA50IBacterial expression of WT mVD1 (2-258) I12KA50I
245896mVD1_I12KA50I_eGFPMammalian expression of I12KA50I mVD1 linked to GFP
245897VinTS_I12KA50IMammalian expression of vinculin tension sensor with I12KA50I double mutation
245898VinTS_I12K/A50I/I997AMammalian expression of vinculin tension sensor with I12K/A50I/I997A triple mutation

Antibodies from Article