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Real-time imaging of protein microenvironment changes in cells with rotor-based fluorescent amino acids.

Yang S, Jin S, Zhang M, Chen Y, Guo Y, Hu Y, Wolynes PG, Xiao H
Nat Chem Biol. 2026 Jan;22(1):97-108. doi: 10.1038/s41589-025-02003-1. Epub 2025 Sep 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
264006pHTN-hSOD-A4VMammalian expression of ALS-associated hSOD1-A4V for protein aggregation imaging experiments.
264007pHTN-hSOD-A4V-W32TAGMammalian expression of hSOD1-A4V bearing W32TAG for site-specific AnapTh incorporation to monitor aggregation-associated microenvironment changes.

Antibodies from Article