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PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis.
Estall JL, Ruas JL, Choi CS, Laznik D, Badman M, Maratos-Flier E, Shulman GI, Spiegelman BM
Proc Natl Acad Sci U S A. 2009 Dec 29. 106(52):22510-5.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
22745pAdTrack-CMV FLAG Rev-Erb alpha
22746pAdTrack-CMV HA ALAS-1
22747pLKO-1 shRev-Erbalpha
22748pAdTrack shALAS-1
22749pAdTrack: shRev-Erbalpha
22750pLKO-1: shALAS-1