ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells.

Wang Q, Mora-Jensen H, Weniger MA, Perez-Galan P, Wolford C, Hai T, Ron D, Chen W, Trenkle W, Wiestner A, Ye Y
Proc Natl Acad Sci U S A. 2009 Feb 17. 106(7):2200-5. (Link opens in a new window) PubMed (Link opens in a new window) Article

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