The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism.
Yang C, Tan W, Whittle C, Qiu L, Cao L, Akbarian S, Xu Z
PLoS One. 2010 . 5(12):e15878.
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 28195 | tdp43-EGFP construct2 | |
| 28196 | tdp43-EGFP construct3 | |
| 28197 | tdp43-EGFP construct4 | |
| 28198 | tdp43-EGFP construct5 | |
| 28199 | tdp43-EGFP construct6 | |
| 28200 | tdp43-EGFP construct7 | |
| 28201 | tdp43-EGFP construct8 | |
| 28202 | tdp43-EGFP construct9 | |
| 28203 | tdp43-EGFP construct10 | |
| 28204 | tdp43-EGFP construct11 | |
| 28205 | wtTDP43tdTOMATOHA | |
| 28206 | TDP43 NOTAG1 | |
| 28207 | TDP43 NOTAG2 | |
| 28208 | TDP43 NOTAG3 | |
| 28209 | TDP43 NOTAG6 | |
| 28210 | TDP43 NOTAG11 | |
| 28211 | miR-TDP43a | |
| 28212 | miR-TDP43b |