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Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.
Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL
Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5163-8. Epub 2007 Mar 2.
PubMed Journal

Plasmids from Article

ID Plasmid  
45547 pcDNA5/FRT-HA-hM3D(Gq) Add to Cart
45548 pcDNA5/FRT-HA-hM4D(Gi) Add to Cart
45549 pcDNA5/FRT-HA-rM3D(Gs) Add to Cart