Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).
    
      Runkle EA, Rice SJ, Qi J, Masser D, Antonetti DA, Winslow MM, Mu D
    
    
      J Biol Chem. 2012 Aug 17;287(34):28790-801. doi: 10.1074/jbc.M112.367987. Epub 2012 Jul 2.
    
    
      
        
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Plasmids from Article
| ID | Plasmid | Purpose | 
|---|---|---|
| 46387 | pGL4.10-Claudin-1 | Claudin-1 promoter reporter assay | 
| 49989 | pcDNA3.1(+)-wt-TTF-1 | For transient transfection to express human wild type TTF-1 protein | 
| 52063 | pcDNA3.1(+)-TTF-1-HDD | It encodes a mutant of TTF-1 in which the homeodomain is deleted | 
| 75084 | pMSCV-hygro-TTF-1 Q210K-Y214M | retroviral vector containing human TTF-1 mutant cDNA | 
| 75264 | pcDNA3.1(+)-TTF-1-Q50K-Y54M | Expresses a double point mutant of human TTF-1 | 
| 75265 | pcDNA3.1(+)-TTF-1-AD1-deletion | Expresses a deletion mutant of human TTF-1 lacking the activation domain 1 | 
| 75266 | pcDNA3.1(+)-TTF-1-AD2-deletion | Expresses a deletion mutant of human TTF-1 lacking the activation domain 2 | 
| 88868 | SFTPB Promoter reporter | Surfactant Protein B Gene Promoter Reporter |