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SOX9 inhibits beta-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.
Deng W, Vanderbilt DB, Lin CC, Martin KH, Brundage KM, Ruppert JM
J Cell Sci. 2015 Jan 27. pii: jcs.162164.
PubMed Article

Plasmids from Article

ID Plasmid  
62967pBABEPuro-HA-GLI1
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62970pLUT7 HA-GLI1
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62972pcDNA3.1 HA-rnSOX9
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62973pcDNA3.1 HA-rnSOX9 ΔC (1-381)
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62975pcDNA3.1 HA-rnSOX9 PQA/S (286-507)
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62976pcDNA3.1 myc-mβTrCP F-box (1-247)
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62977pcDNA3.1 myc-mβTrCP WD1-7 (241-569)
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62978pcDNA3.1 myc-mβTrCP WD2-7 (292-569)
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63009pBABEPuro-rnSOX9
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