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Gcn5 and PCAF negatively regulate interferon-beta production through HAT-independent inhibition of TBK1.
Jin Q, Zhuang L, Lai B, Wang C, Li W, Dolan B, Lu Y, Wang Z, Zhao K, Peng W, Dent SY, Ge K
EMBO Rep. 2014 Nov;15(11):1192-201. doi: 10.15252/embr.201438990. Epub 2014 Sep 30. PubMed Article

Plasmids from Article

ID Plasmid Purpose
63705pMSCVpuro-PCAFretroviral expression of human PCAF in mammalian cells
63706pMSCVpuro-Gcn5retroviral expression of mouse Gcn5 in mammalian cells
63707pMSCVpuro-Gcn5(D608A)retroviral expression of enzyme-dead mouse Gcn5 in mammalian cells
63708pMSCVpuro-F-Gcn5-NLSmretroviral expression of cytoplasm-localized mouse Gcn5 in mammalian cells

Antibodies from Article