We narrowed to 11,593 results for: Vars

1. pcDNA3.1-DDR1-F866Y-V5/HIS

   Plasmid

   #236009

   Purpose

   expression of the F866Y kinase defective mutant variant of human DDR1 that might be associated with lung Adenocarcinoma

   Depositor

   Pavel Krejčí

   Article

   Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

   Insert

   human DDR1-F866Y receptor tyrosine kinase, full length (DDR1 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   F866Y substitution

   Promoter

   CMV

   Available Since

   April 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSG5LHARB1sgresistant

   Plasmid

   #229856

   Purpose

   RB1

   Depositor

   Maria Alvarado-Kristensson

   Article

   Lindstrom et al FASEB J. 2025 Mar 15;39(5):e70431. doi:

   Inserts

   RB1 (RB1 Human)
   Rb1 (RB1 Human)
   

   Tags

   HA (N terminal on backbone)

   Expression

   Mammalian

   Mutation

   changed a bp24 to g; g bp27 to c, and c bp30 to …

   Available Since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-U6-sgCTG-CMV-GFP

   Plasmid

   #216734

   Purpose

   AAV plasmid containing sgCTG (target sequence: (CUG)6) driven by a U6 promoter and eGFP under the control of the CMV promoter. Used for in vivo experiments.

   Depositor

   Vincent Dion

   Article

   Alvaro et al bioRxiv

   Insert

   sgCTG
   

   Use

   AAV and CRISPR

   Expression

   Mammalian

   Promoter

   U6 and CMV

   Available Since

   April 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-nEF-SpCas9D10A nickase

   Plasmid

   #216736

   Purpose

   Expresses SpCas9-D10A nickase from a nEF promoter. For AAV packaging. Derived from pAAV-nEF-SpCas9 (Addgene #87115)

   Depositor

   Vincent Dion

   Article

   Alvaro et al bioRxiv

   Insert

   Cas9-D10A nickase
   

   Use

   AAV and CRISPR

   Expression

   Mammalian

   Mutation

   D10A

   Promoter

   EF-1-alpha core

   Available Since

   April 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. SHIP2-ΔPR1

   Plasmid

   #214902

   Purpose

   expression of the truncated variants of the SHIP2 without first proline-rich domain

   Depositor

   Pavel Krejčí

   Article

   Fafilek et al Sci Signal. 2018 Sep 18;11(548):eaap8608

   Insert

   human SHIP2 delta aa 123-410 (INPPL1 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   delta 123-410aa

   Promoter

   CMV

   Available Since

   April 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. SHIP2-C2

   Plasmid

   #214906

   Purpose

   expression of the truncated variants of the SHIP2 that retains second proline-rich domain

   Depositor

   Pavel Krejčí

   Article

   Fafilek et al Sci Signal. 2018 Sep 18;11(548):eaap8608

   Insert

   human SHIP2 aa 740-1189 (INPPL1 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   delta 1-739, 1190-1258aa

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. SHIP2-C1

   Plasmid

   #214905

   Purpose

   expression of the truncated variants of the SHIP2 that retains second proline-rich domain and C-terminal sterile alpha motif

   Depositor

   Pavel Krejčí

   Article

   Fafilek et al Sci Signal. 2018 Sep 18;11(548):eaap8608

   Insert

   human SHIP2 aa 740-1258 (INPPL1 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   delta 1-739aa

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. SHIP2-N2

   Plasmid

   #214904

   Purpose

   expression of the truncated variants of the SHIP2 that retains first proline-rich domain

   Depositor

   Pavel Krejčí

   Article

   Fafilek et al Sci Signal. 2018 Sep 18;11(548):eaap8608

   Insert

   human SHIP2 aa 123-418 (INPPL1 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   delta 1-122, 419-1258aa

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. SHIP2-N1

   Plasmid

   #214903

   Purpose

   expression of the truncated variants of the SHIP2 that retains only SH2 domain and first proline-rich domain

   Depositor

   Pavel Krejčí

   Article

   Fafilek et al Sci Signal. 2018 Sep 18;11(548):eaap8608

   Insert

   human SHIP2 aa 1-418 (INPPL1 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   delta 419-1258aa

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. CILK1-R272Q

    Plasmid

    #214911

    Purpose

    expression of the mutant variant of CILK1

    Depositor

    Pavel Krejčí

    Article

    Paige Taylor et al Hum Mol Genet. 2016 Sep 15;25(18):3998-4

    Insert

    CILK1 (CILK1 Human)
    

    Tags

    Myc-FLAG

    Expression

    Mammalian

    Mutation

    R272Q substitution

    Promoter

    CMV

    Available Since

    March 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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