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pAd-PRL.Cre

Plasmid

#192937

Purpose

Adenoviral expression vector encoding sgRNAs targeting Trp53, Rb1 and Rbl2 and Cre

Depositor

Thorsten Stiewe

Publication

Merle et al Mol Cancer. 2022 Oct 3;21(1):191. doi: 1

Inserts

Rb1 (Rb1 Mouse)
Trp53 (Trp53 Mouse)
Rbl2 (Rbl2 Mouse)

Use

Adenoviral

Expression

Mammalian

Promoter

U6

Available since

Dec. 9, 2022

Availability

Industry, Academic Institutions, and Nonprofits

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pAd-PR.CC9

Plasmid

#192935

Purpose

Adenoviral expression vector encoding sgRNAs targeting Trp53 and Rb1, Cre and Cas9

Depositor

Thorsten Stiewe

Publication

Merle et al Mol Cancer. 2022 Oct 3;21(1):191. doi: 1

Inserts

Trp53 (Trp53 Mouse)
Rb1 (Rb1 Mouse)

Use

Adenoviral

Expression

Mammalian

Promoter

U6

Available since

Dec. 9, 2022

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-lambdaN-HA-Dm4E-T_1-511-LLFWKtoAAAAA-V5His6_Z

Plasmid

#148160

Purpose

Insect Expression of Dm4E-T_1-511-LLFWKtoAAAAA

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_1-511-LLFWKtoAAAAA (4E-T Fly)

Expression

Insect

Mutation

alias: 4E-T; one non silent mutation L127S, annot…

Available since

May 13, 2022

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-lambdaN-HA-DmNot1_1674-1962-dsRNAres_AC

Plasmid

#148402

Purpose

Insect Expression of DmNot1_1674-1962-dsRNAres

Depositor

Elisa Izaurralde

Publication

Kuzuoglu-Ozturk et al EMBO J. 2016 Jun 1;35(11):1186-203. doi:

Insert

DmNot1_1674-1962-dsRNAres (Not1 Fly)

Expression

Insect

Mutation

2 silent mutations compared to the sequence given…

Available since

March 11, 2022

Availability

Academic Institutions and Nonprofits only

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Anti-BKbeta2 K+ channel [N53/32R]

Plasmid

#177561

Purpose

Mammalian Expression Plasmid of anti-BKbeta2 K+ channel (Mouse). Derived from hybridoma N53/32.

Depositor

James Trimmer

Publication

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

anti-BKbeta2 K+ channel (Mus musculus) recombinant mouse monoclonal antibody (Kcnmb2 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available since

Nov. 24, 2021

Availability

Academic Institutions and Nonprofits only

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SMT215

Plasmid

#134818

Purpose

SMT205 with DHFR-FLAG-tag, western blot

Depositor

Tanja Kortemme

Publication

Thompson et al eLife. 2020 Jul 23;9. pii: 53476. doi: 1

Inserts

Dihydrofolate reductase
Thymidylate synthase

Tags

FLAG

Expression

Bacterial

Mutation

Silent mutations to eliminate internal restrictio…

Promoter

T7 and TET

Available since

Oct. 7, 2020

Availability

Academic Institutions and Nonprofits only

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pRC/CMV-TYK2VF/PA-VSV

Plasmid

#139351

Purpose

Expression of the double mutant of TYK2-V678F-P1104A

Depositor

Sandra Pellegrini

Publication

Li et al J Immunol. 2013 Mar 1;190(5):2335-44. do

Insert

TYK2 cDNA with 267nt of 5' UTR (TYK2 Human)

Tags

VSV

Expression

Mammalian

Mutation

V362F-V678F-P1104A

Promoter

CMV

Available since

June 4, 2020

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(Vps25-g1)-PGKpuroBFP-W

Plasmid

#105033

Purpose

Lentiviral gRNA plasmid targeting mouse Vps25 , co-expression of TagBFP

Depositor

Kosuke Yusa

Publication

Li et al Cell Rep. 2018 Jul 10;24(2):489-502. doi

Insert

Vps25 (Vps25 Mouse)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available since

Sept. 4, 2019

Availability

Academic Institutions and Nonprofits only

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SNRK gRNA (BRDN0001149393)

Plasmid

#76731

Purpose

3rd generation lentiviral gRNA plasmid targeting human SNRK

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SNRK (SNRK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001146259)

Plasmid

#76522

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001149404)

Plasmid

#76523

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001149510)

Plasmid

#76524

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001146192)

Plasmid

#76525

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PIK3CB gRNA (BRDN0001145643)

Plasmid

#76193

Purpose

3rd generation lentiviral gRNA plasmid targeting human PIK3CB

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PIK3CB (PIK3CB Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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WEE2 gRNA (BRDN0001146772)

Plasmid

#75896

Purpose

3rd generation lentiviral gRNA plasmid targeting human WEE2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

WEE2 (WEE2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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WEE2 gRNA (BRDN0001147038)

Plasmid

#75897

Purpose

3rd generation lentiviral gRNA plasmid targeting human WEE2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

WEE2 (WEE2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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WEE2 gRNA (BRDN0001148111)

Plasmid

#75898

Purpose

3rd generation lentiviral gRNA plasmid targeting human WEE2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

WEE2 (WEE2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK3 gRNA (BRDN0001146759)

Plasmid

#75899

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK3

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK3 (SBK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK3 gRNA (BRDN0001147686)

Plasmid

#75900

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK3

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK3 (SBK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK3 gRNA (BRDN0001148159)

Plasmid

#75901

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK3

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK3 (SBK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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