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pGL4.23 A82V/T230A 2014 EBOV + Mucin-Like Domain

Plasmid

#86019

Purpose

Ebola Virus (Makona) Glycoprotein in CMV driven mammalian expression vector

Depositor

Jeremy Luban, Pardis Sabeti

Article

Diehl et al Cell. 2016 Nov 3;167(4):1088-1098.e6. do

Insert

Makona Ebola Virus Glycoprotein

Expression

Mammalian

Mutation

Changed alanine 82 to valine and threonine 230 to…

Promoter

CMV IE

Available Since

Jan. 11, 2017

Availability

Academic Institutions and Nonprofits only

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TEC gRNA (BRDN0001147924)

Plasmid

#77023

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEC

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEC (TEC, TEC Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TEC gRNA (BRDN0001148069)

Plasmid

#77024

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEC

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEC (TEC, TEC Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TEC gRNA (BRDN0001145649)

Plasmid

#77025

Purpose

3rd generation lentiviral gRNA plasmid targeting human TEC

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TEC (TEC, TEC Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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NMRK2 gRNA (BRDN0001145387)

Plasmid

#77130

Purpose

3rd generation lentiviral gRNA plasmid targeting human NMRK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NMRK2 (NMRK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TAF1L gRNA (BRDN0001145988)

Plasmid

#77120

Purpose

3rd generation lentiviral gRNA plasmid targeting human TAF1L

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TAF1L (TAF1L Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TAF1L gRNA (BRDN0001145176)

Plasmid

#77121

Purpose

3rd generation lentiviral gRNA plasmid targeting human TAF1L

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TAF1L (TAF1L Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PLK3 gRNA (BRDN0001146265)

Plasmid

#77470

Purpose

3rd generation lentiviral gRNA plasmid targeting human PLK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PLK3 (PLK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PLK3 gRNA (BRDN0001146656)

Plasmid

#77471

Purpose

3rd generation lentiviral gRNA plasmid targeting human PLK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PLK3 (PLK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PLK3 gRNA (BRDN0001145739)

Plasmid

#77472

Purpose

3rd generation lentiviral gRNA plasmid targeting human PLK3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PLK3 (PLK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PNCK gRNA (BRDN0001145068)

Plasmid

#77328

Purpose

3rd generation lentiviral gRNA plasmid targeting human PNCK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PNCK (PNCK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PTK2B gRNA (BRDN0001147875)

Plasmid

#76388

Purpose

3rd generation lentiviral gRNA plasmid targeting human PTK2B

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PTK2B (PTK2B Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PRKCI gRNA (BRDN0001146507)

Plasmid

#76400

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKCI

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKCI (PRKCI Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PRKCI gRNA (BRDN0001162218)

Plasmid

#76403

Purpose

3rd generation lentiviral gRNA plasmid targeting human PRKCI

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PRKCI (PRKCI Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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PANK2 gRNA (BRDN0001149459)

Plasmid

#76809

Purpose

3rd generation lentiviral gRNA plasmid targeting human PANK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PANK2 (PANK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MPP1 gRNA (BRDN0001149326)

Plasmid

#77804

Purpose

3rd generation lentiviral gRNA plasmid targeting human MPP1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MPP1 (MPP1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SMG1 gRNA (BRDN0001149508)

Plasmid

#75772

Purpose

3rd generation lentiviral gRNA plasmid targeting human SMG1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SMG1 (SMG1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HNF4A_P2-285/-169

Plasmid

#31052

Depositor

Gerhart Ryffel

Article

Wirsing et al Diabet Med. 2010 Jun . 27(6):631-5.

Insert

HNF4A P2 promoter (HNF4A Human)

Use

Luciferase

Expression

Mammalian

Mutation

-285 to -1 of P2 HNF4A promoter with mutation -16…

Available Since

Oct. 6, 2011

Availability

Academic Institutions and Nonprofits only

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HNF4A_P2-285/-136

Plasmid

#31051

Depositor

Gerhart Ryffel

Article

Wirsing et al Diabet Med. 2010 Jun . 27(6):631-5.

Insert

HNF4A P2 promoter (HNF4A Human)

Use

Luciferase

Expression

Mammalian

Mutation

-285 to -1 of P2 HNF4A promoter with mutation -13…

Available Since

Oct. 6, 2011

Availability

Academic Institutions and Nonprofits only

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NUP62 gRNA (BRDN0001148646)

Plasmid

#77670

Purpose

3rd generation lentiviral gRNA plasmid targeting human NUP62

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NUP62 (NUP62 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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