We narrowed to 414 results for: SAM activators

1. lentiSAMv2 C2CD4A/B-enh1-guide1

   Plasmid

   #125465

   Purpose

   CRISPR-mediated activation of human islet enhancer containing T2D-associated variant rs182222907 (C2CD4A/B GWAS locus)

   Depositor

   Jorge Ferrer

   Article

   Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

   Insert

   dCas9-VP64-2A-BlastR
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a core and U6

   Available Since

   July 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-CAG-mCherry-Tandem-PSAM4-GlyR

   Plasmid

   #208361

   Purpose

   Expression of the inhibitory chemogenetic tool PSAM4-GlyR and mCherry reporter. Application of ultrapotent agonists induces neuronal silencing.

   Depositor

   David Bennett

   Article

   Perez-Sanchez et al Sci Transl Med. 2023 Oct 4;15(716):eadh3

   Insert

   mCherry-TANDEM-PSAM4-GlyR
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   Oct. 13, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. rAAV-syn::FLEX-rev::PSAML141F,Y115F:5HT3HC-IRES-GFP

   Plasmid

   #32477

   Purpose

   Cre-dependent expression of PSAM-5HT3 HC (L141F,Y115F) neuronal activator, with IRES-EGFP marker

   Depositor

   Scott Sternson

   Article

   Magnus et al Science. 2011 Sep 2;333(6047):1292-6.

   Insert

   PSAML141F,Y115F-5HT3HC
   

   Use

   AAV and Cre/Lox; Adeno-associated virus, flex swi…

   Tags

   IRES-EGFP

   Promoter

   Synapsin

   Available Since

   Jan. 12, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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4. rAAV-syn::FLEX-rev::PSAMQ79G,Q139G:5HT3HC-IRES-GFP

   Plasmid

   #32475

   Purpose

   Cre-dependent expression of PSAM-5HT3 HC (Q79G,Q139G) neuronal activator, with IRES-EGFP marker

   Depositor

   Scott Sternson

   Article

   Magnus et al Science. 2011 Sep 2;333(6047):1292-6.

   Insert

   PSAMQ79G,Q139G-5HT3HC
   

   Use

   AAV and Cre/Lox; Adeno-associated virus, flex swi…

   Tags

   IRES-EGFP

   Promoter

   Synapsin

   Available Since

   Dec. 12, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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5. Human SAM library in lentiSAMv2 backbone

   Pooled Library

   #1000000078

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   Feng Zhang

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

6. Human SLC SAM Library

   Pooled Library

   #132561

   Purpose

   Expresses gRNAs for activation of human Solute Carrier family genes

   Depositor

   Giulio Superti-Furga

   Article

   Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   May 18, 2020

   Availability

   Academic Institutions and Nonprofits only

7. Human SAM library in lenti sgRNA(MS2)_puro backbone

   Pooled Library

   #1000000074

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of mouse genes

   Depositor

   Feng Zhang

   Available Since

   March 17, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human SAM Library in lenti sgRNA(MS2)_zeo backbone

   Pooled Library

   #1000000057

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   Feng Zhang

   Available Since

   Jan. 16, 2015

   Availability

   Academic Institutions and Nonprofits only

9. Mouse SAM Library in lenti sgRNA(MS2)_puro optimized backbone

   Pooled Library

   #1000000075

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of mouse genes

   Depositor

   Feng Zhang

   Available Since

   March 17, 2016

   Availability

   Academic Institutions and Nonprofits only

10. pYJ15-PB-U6-Nkx6.1-acti-gRNA1

    Plasmid

    #131059

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA1 (NKX6-1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pYJ16-PB-U6-Nkx6.1-acti-gRNA2

    Plasmid

    #131060

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA2 (NKX6-1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pYJ17-PB-U6-Nkx6.1-acti-gRNA3

    Plasmid

    #131061

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA3 (NKX6-1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pYJ12-PB-U6-ND1-acti-gRNA1

    Plasmid

    #131056

    Purpose

    Activation of NeuroD1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NeuroD1 activation gRNA1 (NEUROD1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pYJ13-PB-U6-ND1-acti-gRNA2

    Plasmid

    #131057

    Purpose

    Activation of NeuroD1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NeuroD1 activation gRNA2 (NEUROD1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pYJ14-PB-U6-ND1-acti-gRNA3

    Plasmid

    #131058

    Purpose

    Activation of NeuroD1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NeuroD1 activation gRNA3 (NEUROD1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pYJ23-lenti-MS2-U6-NKX6.1-acti-gRNA1

    Plasmid

    #131067

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA1 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pYJ24-lenti-MS2-U6-NKX6.1-acti-gRNA2

    Plasmid

    #131068

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA2 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pYJ25-lenti-MS2-U6-NKX6.1-acti-gRNA3

    Plasmid

    #131069

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA3 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. gRNA-10Xcapture-PuroR

    Plasmid

    #211496

    Purpose

    Plasmid for the expression of SAM-compatible gRNA for CRISPRa with capturer sequence for 10X Genomics sequencing

    Depositor

    Lesley Forrester, Antonella Fidanza

    Article

    Petazzi et al Elife. 2024 Dec 23;13:RP94884. doi: 10.7

    Inserts

    U6-gRNA
    Ef1a-PuroR
    

    Use

    CRISPR, Lentiviral, and Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF1a and U6

    Available Since

    Dec. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pYJ29-lenti-U6-SOX17-acti-gRNA-DsRed

    Plasmid

    #131072

    Purpose

    Activation of SOX17 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    SOX17 activation gRNA (SOX17 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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