One reporter for in-cell activity profiling of majority of protein kinase oncogenes.
Gudernova I, Foldynova-Trantirkova S, Ghannamova BE, Fafilek B, Varecha M, Balek L, Hruba E, Jonatova L, Jelinkova I, Kunova Bosakova M, Trantirek L, Mayer J, Krejci P
Elife. 2017 Feb 15;6. pii: e21536. doi: 10.7554/eLife.21536. PubMed Article
Gudernova I, Foldynova-Trantirkova S, Ghannamova BE, Fafilek B, Varecha M, Balek L, Hruba E, Jonatova L, Jelinkova I, Kunova Bosakova M, Trantirek L, Mayer J, Krejci P
Elife. 2017 Feb 15;6. pii: e21536. doi: 10.7554/eLife.21536. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 200109 | pKrox24(2xD-E_inD)Luc | Luciferase reporter for in cell monitoring of receptor tyrosine kinase-MAP ERK pathway activity |
| 200110 | pKrox24(2xD-E)dTomato | Fluorescent reporter for in cell monitoring of receptor tyrosine kinase-MAP ERK pathway activity |
| 200111 | pKrox24(2xD-E)DsRed | Fluorescent reporter for in cell monitoring of receptor tyrosine kinase-MAP ERK pathway activity |
| 200112 | pKrox24(MapErk)Luc | Luciferase reporter for in cell monitoring of receptor tyrosine kinase-MAP ERK pathway activity |
| 200113 | pKrox24(MapErk)dTomato | Fluorescent reporter for in cell monitoring of receptor tyrosine kinase-MAP ERK pathway activity |
| 200114 | pKrox24(MapErk)DsRed | Fluorescent reporter for in cell monitoring of receptor tyrosine kinase-MAP ERK pathway activity |
| 200115 | pcDNA3.1-ALK-V5/HIS | Expression of human ALK receptor tyrosine kinase in mammalian cells |
| 200116 | pcDNA3.1-LTK-V5/HIS | Expression of human LTK receptor tyrosine kinase in mammalian cells |
| 200117 | pcDNA3.1-AXL-V5/HIS | Expression of human AXL receptor tyrosine kinase in mammalian cells |
| 200118 | pcDNA3.1-TYRO3-V5/HIS | Expression of human TYRO3 receptor tyrosine kinase in mammalian cells |
| 201100 | pcDNA3.1-DDR1-V5/HIS | expression of human DDR1 receptor tyrosine kinase in mammalian cells |
| 201101 | pcDNA3.1-DDR2-V5/HIS | expression of human DDR2 receptor tyrosine kinase in mammalian cells |
| 201102 | pcDNA3.1-EGFR-V5/HIS | expression of human EGFR receptor tyrosine kinase in mammalian cells |
| 201103 | pcDNA3.1-ERBB2-V5/HIS | expression of human ERBB2 receptor tyrosine kinase in mammalian cells |
| 201104 | pcDNA3.1-ERBB3-V5/HIS | expression of human ERBB3 receptor tyrosine kinase in mammalian cells |
| 201105 | pcDNA3.1-ERBB4-V5/HIS | expression of human ERBB4 receptor tyrosine kinase in mammalian cells |
| 201106 | pcDNA3.1-FGFR1c-V5/HIS | expression of human FGFR1 receptor tyrosine kinase in mammalian cells |
| 201107 | pcDNA3.1-FGFR2c-V5/HIS | expression of human FGFR2 receptor tyrosine kinase in mammalian cells |
| 201108 | pcDNA3.1-FGFR3c-V5/HIS | expression of human FGFR3 receptor tyrosine kinase in mammalian cells |
| 201109 | pcDNA3.1-FGFR4-V5/HIS | expression of human FGFR4 receptor tyrosine kinase in mammalian cells |
| 201979 | pcDNA3.1-IGF1R-V5/HIS | expression of human IGF1R receptor tyrosine kinase in mammalian cells |
| 201980 | pcDNA3.1-INSR-V5/HIS | expression of human INSR receptor tyrosine kinase in mammalian cells |
| 201981 | pcDNA3.1-INSRR-V5/HIS | expression of human INSRR receptor tyrosine kinase in mammalian cells |
| 201982 | pcDNA3.1-MET-V5/HIS | expression of human MET receptor tyrosine kinase in mammalian cells |
| 201983 | pcDNA3.1-RON-V5/HIS | expression of human RON receptor tyrosine kinase in mammalian cells |
| 201984 | pcDNA3.1-CSF1R-V5/HIS | expression of human CSF1R receptor tyrosine kinase in mammalian cells |
| 201985 | pcDNA3.1-FLT3-V5/HIS | expression of human FLT3 receptor tyrosine kinase in mammalian cells |
| 201987 | pcDNA3.1-PDGFRA-V5/HIS | expression of human PDGFRA receptor tyrosine kinase in mammalian cells |
| 201988 | pcDNA3.1-PDGFRB-V5/HIS | expression of human PDGFRB receptor tyrosine kinase in mammalian cells |
| 205606 | pcDNA3.1-RET-V5/HIS | Expression of human RET receptor tyrosine kinase in mammalian cells |
| 205607 | pcDNA3.1-ROR1-V5/HIS | Expression of human ROR1 receptor tyrosine kinase in mammalian cells |
| 205608 | pcDNA3.1-ROR2-V5/HIS | Expression of human ROR2 receptor tyrosine kinase in mammalian cells |
| 205609 | pcDNA3.1-ROS1-V5/HIS | Expression of human ROS1 receptor tyrosine kinase in mammalian cells |
| 205610 | pcDNA3.1-RYK-V5/HIS | Expression of human RYK receptor tyrosine kinase in mammalian cells |
| 205611 | pcDNA3.1-TEK-V5/HIS | Expression of human TEK receptor tyrosine kinase in mammalian cells |
| 205612 | pcDNA3.1-TIE-V5/HIS | Expression of human TIE receptor tyrosine kinase in mammalian cells |
| 205614 | pcDNA3.1-TRKB-V5/HIS | Expression of human TRKB receptor tyrosine kinase in mammalian cells |
| 205615 | pcDNA3.1-TRKC-V5/HIS | Expression of human TRKC receptor tyrosine kinase in mammalian cells |
| 205616 | pcDNA3.1-VEGFR1-V5/HIS | Expression of human VEGFR1 receptor tyrosine kinase in mammalian cells |
| 205617 | pcDNA3.1-VEGFR2-V5/HIS | Expression of human VEGFR2 receptor tyrosine kinase in mammalian cells |
| 205618 | pcDNA3.1-VEGFR3-V5/HIS | Expression of human VEGFR3 receptor tyrosine kinase in mammalian cells |