We narrowed to 4,520 results for: gca

1. ZAP70 gRNA (BRDN0001487050)

   Plasmid

   #77956

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ZAP70

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ZAP70 (ZAP70 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. pKIF1C-2xFLAG

   Plasmid

   #130979

   Purpose

   Expression of KIF1C-2xFLAG in mammalian cells.

   Depositor

   Anne Straube

   Article

   Theisen et al Dev Cell. 2012 Dec 11;23(6):1153-66. doi

   Insert

   KIF1C-2xFLAG (KIF1C Human)
   

   Use

   Tags

   2xFLAG

   Expression

   Mammalian

   Mutation

   4 silent mutations that make this construct resis…

   Promoter

   CMV

   Available since

   Oct. 15, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. PRKCI gRNA (BRDN0001148989)

   Plasmid

   #76401

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PRKCI

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PRKCI (PRKCI Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. TRIM24 gRNA (BRDN0001148301)

   Plasmid

   #77888

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human TRIM24

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   TRIM24 (TRIM24 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. PIP4K2B gRNA (BRDN0001147019)

   Plasmid

   #77903

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PIP4K2B

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PIP4K2B (PIP4K2B Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. CCL2 gRNA (BRDN0001145563)

   Plasmid

   #77866

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CCL2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CCL2 gRNA (CCL2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. PPIP5K1 gRNA (BRDN0001148626)

   Plasmid

   #76308

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PPIP5K1

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PPIP5K1 (PPIP5K1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. p426_Cas9_gRNA-YOLCd1b

   Plasmid

   #87401

   Purpose

   All-in-one CRISPR plasmid for integrating, deleting, or replacing a gene in S. cerevisiae. High-copy, URA3 plasmid contains human codon-optimized Cas9 and a guide RNA targeting YOLCd1b sequence GACTAGTTAAGCGAGCATGT in yeast chromosome 15.

   Depositor

   Aindrila Mukhopadhyay

   Article

   Reider Apel et al Nucleic Acids Res. 2017 Jan 9;45(1):496-

   Insert

   Human Optimized S. pyogenes Cas9 and guide RNA targeting YOLCd1b
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   ADH1, pTyrosine

   Available since

   April 5, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. RET gRNA (BRDN0001149257)

   Plasmid

   #77499

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human RET

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   RET (RET Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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10. PAK3 gRNA (BRDN0001148485)

    Plasmid

    #75680

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PAK3

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PAK3 (PAK3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLKO.1puro-shWillin-A

    Plasmid

    #40885

    Depositor

    Paul Reynolds

    Article

    Angus et al Oncogene. 2012 Jan 12;31(2):238-50. doi:

    Insert

    shWillin-A (FRMD6 Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 5, 2012

    Availability

    Academic Institutions and Nonprofits only

12. pLentiCRISPR-v1-sgABCC4_1

    Plasmid

    #217433

    Purpose

    Lentiviral vector expressing Cas9 and an sgRNA targeting human ABCC4

    Depositor

    Jason Cantor

    Article

    Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

    Insert

    sgRNA 1 targeting ABCC4 (ABCC4 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Jan. 31, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pUC-hU6-crCoV-Mutiplex_EF1a-BFP

    Plasmid

    #224788

    Purpose

    SARS-COV-2 targeting crRNA array for RfxCas13d expressed from single hU6 promoter and reporter BFP protein expressed from EF1a promoter

    Depositor

    Gabor Balazsi

    Article

    Wan et al ACS Synth Biol. 2024 Oct 18;13(10):3212-

    Insert

    crCoV20, crCoV21, crCoV24
    

    Use

    CRISPR and Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6 and hU6-2xTetO

    Available since

    Oct. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAPM-miR30-DDX3X-ts2

    Plasmid

    #174236

    Purpose

    DDX3X knockdown

    Depositor

    Jeremy Luban

    Article

    Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

    Insert

    DDX3X shRNA (DDX3X Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    SFFV

    Available since

    Aug. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pKLV2-U6gRNA5(PRDM14_v32_7-6)-PGKpuroBFP-W

    Plasmid

    #211983

    Purpose

    Express gRNA against PRDM14 with puro and BFP

    Depositor

    Kosuke Yusa

    Article

    Ishikawa et al Commun Biol. 2023 Dec 28;6(1):1290. doi:

    Insert

    sgRNA targeting PRDM14 (PRDM14 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Human U6 promoter

    Available since

    Jan. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pKLV2-U6gRNA5(MRPS26(15))-PGKpuro2ABFP-W

    Plasmid

    #200499

    Purpose

    Lentiviral vector expressing gRNA targeting human MRPS26

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    MRPS26(15) (MRPS26 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pKLV2-U6gRNA5(MRPS26(12))-PGKpuro2ABFP-W

    Plasmid

    #200498

    Purpose

    Lentiviral vector expressing gRNA targeting human MRPS26

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    MRPS26(12) (MRPS26 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. INS-3'gRNA

    Plasmid

    #210468

    Purpose

    gRNA targeting INS 3' terminal for CRISPR-Cas9-mediated knock-in

    Depositor

    Kai Wang

    Article

    Zhao et al STAR Protoc. 2024 May 23;5(2):103084. do

    Insert

    INS (INS Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. Lenti-sgNkx2-1#1/Cre

    Plasmid

    #193221

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Nkx2-1 gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgNkx2-1#1 (Nkx2-1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Feb. 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pAP14

    Plasmid

    #186262

    Purpose

    wgaA (a.k.a expA1) and wgaB (a.k.a expA23), bicistronic, under light light responsive PEL222 promoter and EL222 under constitutively active LacIq promoter

    Depositor

    Yongku Cho

    Article

    Pirhanov et al ACS Synth Biol. 2021 Feb 19;10(2):345-35

    Inserts

    wgaAB bicistronic
    EL222 (ELI_04755 Erythrobacter litoralis)
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    LacIq (CGAATGGTGCAAAACCTTTCGCGGTATGGCATGATAGCGCCC…

    Available since

    Aug. 15, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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