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FUS_LC_withR

Plasmid

#139128

Purpose

express FUS LC with the same number and spacing of arginines as hnRNPA2 LC

Depositor

Nicolas Fawzi

Article

Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

Insert

FUS (FUS Human)

Expression

Bacterial

Mutation

add arginines

Available Since

Dec. 7, 2020

Availability

Academic Institutions and Nonprofits only

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hnRNPA2_LC_nocharge_wR

Plasmid

#139119

Purpose

express hnRNPA2 LC with no charged residues with R added back

Depositor

Nicolas Fawzi

Article

Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

Insert

hnRNPA2 (HNRNPA2B1 Human)

Expression

Bacterial

Mutation

remove all K, most D

Available Since

Dec. 7, 2020

Availability

Academic Institutions and Nonprofits only

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FUS_LC_charge

Plasmid

#139126

Purpose

express FUS LC with an hnRNPA2 LC-like charge patterning

Depositor

Nicolas Fawzi

Article

Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

Insert

FUS (FUS Human)

Expression

Bacterial

Mutation

Add R, K, D to make FUS LC have similar charge pa…

Available Since

Dec. 7, 2020

Availability

Academic Institutions and Nonprofits only

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pEGFP-TDP-43 (NLSmut)

Plasmid

#235489

Purpose

Expression of human TDP-43-EGFP with mutated nuclear localization sequence

Depositor

Maxime Rousseaux

Article

Suk et al Mol Neurodegener. 2025 Mar 28;20(1):38.

Insert

TARDBP (TARDBP Human)

Tags

EGFP

Expression

Mammalian

Mutation

K82A, R83A, K84A, K95A, K97A, R98A

Available Since

May 19, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pEGFP-TDP-43 (Q331K)

Plasmid

#235488

Purpose

Expression of human TDP-43-EGFP with human ALS-causing Q331K mutation

Depositor

Maxime Rousseaux

Article

Suk et al Mol Neurodegener. 2025 Mar 28;20(1):38.

Insert

TARDBP (TARDBP Human)

Tags

EGFP

Expression

Mammalian

Mutation

Q331K

Available Since

April 30, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pEGFP-TDP-43 (5FL)

Plasmid

#235491

Purpose

Expression of human RNA-binding deficient TDP-43-EGFP

Depositor

Maxime Rousseaux

Article

Suk et al Mol Neurodegener. 2025 Mar 28;20(1):38.

Insert

TARDBP (TARDBP Human)

Tags

EGFP

Expression

Mammalian

Mutation

F124L, F127L, F147L, F149L, F152L

Available Since

April 30, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pRRLSIN.cPPT.PGK.MD(ND2bHLH).WPRE

Plasmid

#122055

Purpose

Lentiviral expression of a MyoD chimeric protein substituted with the NeuroD2 bHLH domain

Depositor

Stephen Tapscott

Article

Fong et al Cell Rep. 2015 Mar 31;10(12):1937-46. do

Insert

MD(ND2bHLH) (Myod1, Neurod2 Mouse)

Use

Lentiviral

Expression

Mammalian

Mutation

MyoD chimeric protein substituted with the NeuroD…

Available Since

March 12, 2019

Availability

Academic Institutions and Nonprofits only

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pEGFP-TDP-43 (4SA)

Plasmid

#235499

Purpose

Expression of human TDP-43-EGFP with phospho-dead mutations in the C-terminus

Depositor

Maxime Rousseaux

Article

Suk et al Mol Neurodegener. 2025 Mar 28;20(1):38.

Insert

TARDBP (TARDBP Human)

Tags

EGFP

Expression

Mammalian

Mutation

S403A, S404A, S409A, S410A

Available Since

April 30, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pEGFP-TDP-43 (2KR)

Plasmid

#235494

Purpose

Expression of human TDP-43-EGFP with K136R and K408R mutations

Depositor

Maxime Rousseaux

Article

Suk et al Mol Neurodegener. 2025 Mar 28;20(1):38.

Insert

TARDBP (TARDBP Human)

Tags

EGFP

Expression

Mammalian

Mutation

K136R, K408R

Available Since

April 30, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pEGFP-TDP-43 (K408R)

Plasmid

#235493

Purpose

Expression of human TDP-43-EGFP with K408R mutation to block SUMOylation

Depositor

Maxime Rousseaux

Article

Suk et al Mol Neurodegener. 2025 Mar 28;20(1):38.

Insert

TARDBP (TARDBP Human)

Tags

EGFP

Expression

Mammalian

Mutation

K408R

Available Since

April 30, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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