We narrowed to 31,919 results for: Eng

1. pAAV-hSyn-GRAB_DA1m

   Plasmid

   #113049

   Purpose

   express the genetically-encoded fluorescent dopamine(DA) sensor GRAB_DA1m in neurons

   Depositor

   Yulong Li

   Article

   Sun et al Cell. 2018 Jul 12;174(2):481-496.e19. do

   Has Service

   AAV9

   Insert

   GPCR activation based DA sensor GRAB_DA1m (DRD2 Human)
   

   Use

   AAV

   Promoter

   hSyn

   Available Since

   Aug. 3, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCDH-3_Flag-YTHDF2-D-MUT (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232947

   Purpose

   Expresses the domain-mutant YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-D-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Mutation

   5 site mutation (Y418A+D422A+W432A+W486A+W491A), …

   Available Since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCDH-3_Flag-YTHDF2 (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232945

   Purpose

   Expresses YTHDF2 with synonymous mutations rendering it resistant to sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2 (YTHDF2 Human)
   

   Use

   Lentiviral

   Mutation

   synonymous mutation

   Available Since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCDH-3_Flag-YTHDF2-m(6)A-MUT (nonsense mutation of sgYTHDF2-1)

   Plasmid

   #232946

   Purpose

   Expresses the m6A-binding-deficient mutant of YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-m(6)A-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Mutation

   2 site mutation (W432A+W486A), synonymous mutation

   Available Since

   May 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. PCDH-Mut-ALKBH5-3xFLAG

   Plasmid

   #203737

   Purpose

   Overexpression of ALKBH5-Mut

   Depositor

   Jianjun Chen

   Article

   Shen et al Cell Stem Cell. 2020 Jul 2;27(1):64-80.e

   Insert

   ALKBH5 (ALKBH5 Human)
   

   Use

   Lentiviral

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Enzyme Inactive Mutation (H226A)

   Available Since

   July 31, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-hSyn-GRAB_DA1h

   Plasmid

   #113050

   Purpose

   express the genetically-encoded fluorescent dopamine(DA) sensor GRAB_DA1h in neurons

   Depositor

   Yulong Li

   Article

   Sun et al Cell. 2018 Jul 12;174(2):481-496.e19. do

   Has Service

   AAV Retrograde and AAV9

   Insert

   GPCR activation based DA sensor GRAB_DA1h (DRD2 Human)
   

   Use

   AAV

   Promoter

   hSyn

   Available Since

   Aug. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCDH-3_Flag-YTHDF2-m6A-MUT

   Plasmid

   #238976

   Purpose

   Expresses the m6A-binding-deficient mutant of YTHDF2

   Depositor

   Jianjun Chen

   Article

   Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

   Insert

   YTHDF2-m6A-MUT (YTHDF2 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   2 site mutation (W432A+W486A)

   Available Since

   June 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. peSCBE3-NG-HF1-Hypa

   Plasmid

   #218166

   Purpose

   This plasmid harbors the base editor eSCBE3-NG-HF1-Hypa along with an sgRNA cloning cassette, facilitating high-efficiency and high-fidelity base editing at targets bearing NG PAM in Streptomyces.

   Depositor

   Yuhui Sun

   Article

   Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:

   Inserts

   escbe3-NG-HF1-Hypa
   a programmable sgRNA cloning cassette
   

   Use

   CRISPR; Sgrna transcription

   Expression

   Bacterial

   Mutation

   Mutation in the portion of deaminase hAPOBEC3A : …

   Promoter

   rpsL promoter

   Available Since

   May 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pGL3-basic-FTO promoter_WT

   Plasmid

   #108922

   Purpose

   The core promoter region of FTO was inserted into pGL3 basic vector

   Depositor

   Jianjun Chen

   Article

   Su et al Cell. 2018 Jan 11;172(1-2):90-105.e23. d

   Insert

   FTO (FTO Human)
   

   Tags

   NA

   Expression

   Mammalian

   Mutation

   NA

   Available Since

   May 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. peSCBE3-NG-HF1

    Plasmid

    #218164

    Purpose

    This plasmid harbors the base editor eSCBE3-NG-HF1 along with an sgRNA cloning cassette, facilitating high-efficiency and high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces.

    Depositor

    Yuhui Sun

    Article

    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:

    Inserts

    escbe3-NG-HF1
    a programmable sgRNA cloning cassette
    

    Use

    CRISPR; Sgrna transcription

    Expression

    Bacterial

    Mutation

    Mutation in the portion of deaminase hAPOBEC3A : …

    Promoter

    rpsL promoter

    Available Since

    May 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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