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SNRK gRNA (BRDN0001149393)

Plasmid

#76731

Purpose

3rd generation lentiviral gRNA plasmid targeting human SNRK

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SNRK (SNRK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001146259)

Plasmid

#76522

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001149404)

Plasmid

#76523

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001149510)

Plasmid

#76524

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR1C gRNA (BRDN0001146192)

Plasmid

#76525

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR1C

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR1C (ACVR1C Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK3 gRNA (BRDN0001146759)

Plasmid

#75899

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK3

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK3 (SBK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK3 gRNA (BRDN0001147686)

Plasmid

#75900

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK3

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK3 (SBK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK3 gRNA (BRDN0001148159)

Plasmid

#75901

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK3

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK3 (SBK3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK2 gRNA (BRDN0001146871)

Plasmid

#75881

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK2 (SBK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK2 gRNA (BRDN0001147500)

Plasmid

#75882

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK2 (SBK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK2 gRNA (BRDN0001162195)

Plasmid

#75883

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK2 (SBK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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SBK2 gRNA (BRDN0001162192)

Plasmid

#75884

Purpose

3rd generation lentiviral gRNA plasmid targeting human SBK2

Depositor

John Doench, David Root

Publication

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

SBK2 (SBK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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Sema6d.x-AP-His

Plasmid

#72047

Purpose

Expresses the extracellular region of the Sema6D, isoform x protein, C-terminally fused to alkaline phosphatase + 6X histidine tag.

Depositor

Woj Wojtowicz

Publication

Visser et al Elife. 2015 Dec 3;4. pii: e08149. doi: 1

Insert

Sema6d.x (Sema6d Human, Mouse)

Tags

AP-His

Expression

Mammalian

Promoter

CMV

Available since

Feb. 18, 2016

Availability

Academic Institutions and Nonprofits only

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pEGFP C1 SADBs shRNA Resistant

Plasmid

#67155

Purpose

pEGFP containing N-terminally EGFP Tagged mouse SADBs resistant to an shRNA

Depositor

Maria Alvarado-Kristensson, Ana Carrera

Publication

Alvarado-Kristensson et al Nat Cell Biol. 2009 Sep;11(9):1081-92. d

Insert

Brsk1 (Brsk1 Mouse)

Tags

EGFP

Expression

Mammalian

Mutation

nucleotide 294 C-T, nucleotide 297 C-G

Promoter

CMV

Available since

July 8, 2015

Availability

Academic Institutions and Nonprofits only
PA-mCherry-miniSOG-Alpha-Actinin-19

Plasmid

#57782

Purpose

Localization: Alpha Actinin, Excitation: 448 / 473, Emission: 500 / 528

Depositor

Michael Davidson

Publication

Shu et al PLoS Biol. 2011 Apr;9(4):e1001041. doi:

Insert

Alpha-Actinin (ACTN1 Human)

Tags

PA-mCherry-miniSOG

Expression

Mammalian

Promoter

CMV

Available since

Jan. 29, 2015

Availability

Academic Institutions and Nonprofits only
pCMV-HA-mIFITM3-K24,88,104A

Plasmid

#58406

Purpose

Expresses murine IFITM3-K24,88,104A with an N-terminal HA tag in mammalian cells

Depositor

Howard Hang, Jacob Yount

Publication

Yount et al J Biol Chem. 2012 Jun 1;287(23):19631-41

Insert

IFITM3 (Ifitm3 Mouse)

Tags

HA

Expression

Mammalian

Mutation

Lysines 24, 88, and 104 to Alanine

Promoter

CMV IE

Available since

Sept. 8, 2014

Availability

Academic Institutions and Nonprofits only
pCMV-HA-mIFITM3-H136T

Plasmid

#58413

Purpose

Expresses murine IFITM3-H136T with an N-terminal HA tag in mammalian cells (adds a possible glycosylation site)

Depositor

Howard Hang, Jacob Yount

Publication

Yount et al J Biol Chem. 2012 Jun 1;287(23):19631-41

Insert

IFITM3 (Ifitm3 Mouse)

Tags

HA

Expression

Mammalian

Mutation

Histidine 236 to Threonine

Promoter

CMV IE

Available since

Sept. 8, 2014

Availability

Academic Institutions and Nonprofits only
pCMV-HA-mIFITM3-K24,83,104A

Plasmid

#58407

Purpose

Expresses murine IFITM3-K24,83,104A with an N-terminal HA tag in mammalian cells

Depositor

Howard Hang, Jacob Yount

Publication

Yount et al J Biol Chem. 2012 Jun 1;287(23):19631-41

Insert

IFITM3 (Ifitm3 Mouse)

Tags

HA

Expression

Mammalian

Mutation

Lysines 24, 83, and 104 to Alanine

Promoter

CMV IE

Available since

Sept. 8, 2014

Availability

Academic Institutions and Nonprofits only
pCMV-HA-mIFITM3-K104A

Plasmid

#58403

Purpose

Expresses murine IFITM3-K104A with an N-terminal HA tag in mammalian cells

Depositor

Howard Hang, Jacob Yount

Publication

Yount et al J Biol Chem. 2012 Jun 1;287(23):19631-41

Insert

IFITM3 (Ifitm3 Mouse)

Tags

HA

Expression

Mammalian

Mutation

Lysine 104 to Alanine

Promoter

CMV IE

Available since

Sept. 4, 2014

Availability

Academic Institutions and Nonprofits only
pSBinit-Syb-BC10(Y35A/Y107A/W108S)

Plasmid

#250413

Purpose

Expression of Anti-SLC66A2 Sybody Non-Binding Variant in Bacteria

Depositor

Simon Newstead

Insert

Syb-BC10

Use

Affinity Reagent/ Antibody

Tags

Myc-6xHis and PelB

Expression

Bacterial

Mutation

CDR1(Y35A)/CDR3(Y107A/W108S)

Promoter

araBAD

Available since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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