We narrowed to 23,504 results for: c myc

1. pcDNA3.1-GSDMD_29-484

   Plasmid

   #218231

   Purpose

   Gasdermin-D_29-484 is a non-functional GSDMD formed by SARS-CoV-2 3CLpro cleavage in the N-terminal domain. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD (GSDMD Human)
   

   Tags

   flag

   Expression

   Mammalian

   Mutation

   construct only codes for amino acids 29-484

   Available Since

   July 1, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pcDNA3.1-GSDMD_29-270

   Plasmid

   #218232

   Purpose

   Gasdermin-D_29-270 is a non-functional GSDMD formed by two SARS-CoV-2 3CLpro cleavages. Transfection in HEK293 cells showed no pore-forming activity or induction of pyroptosis

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD (GSDMD Human)
   

   Tags

   flag

   Expression

   Mammalian

   Mutation

   construct only codes for amino acids 29-270

   Available Since

   July 1, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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3. pLV-PB2_Lock1-I436C+S993C

   Plasmid

   #182879

   Purpose

   Lentivirus for expression of Plexin-B2 locked ring mutant

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2025 Jan 2;16(1):272. doi: 1

   Insert

   hPLXNB2 (PLXNB2 Human)
   

   Use

   Lentiviral

   Mutation

   changed Isoleucine 436 to Cysteine and Serine 993…

   Available Since

   Jan. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLV-PB2_Lock2-I436C+T1051C

   Plasmid

   #182880

   Purpose

   Lentivirus for expression of Plexin-B2 locked ring mutant

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2025 Jan 2;16(1):272. doi: 1

   Insert

   hPLXNB2 (PLXNB2 Human)
   

   Use

   Lentiviral

   Mutation

   changed Isoleucine 436 to Cysteine and Threonine …

   Available Since

   Jan. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pEF2-EFGR-hTyro

   Plasmid

   #225998

   Purpose

   Expresses a chimeric construct having N-terminal human EGFR and C-terminal human Tyro3

   Depositor

   Raymond Birge, Sergei Kotenko

   Article

   Kimani et al Cell Commun Signal. 2016 Sep 6;14(1):19.

   Insert

   human EGFR N-Terminal human Tyro3 C-Terminal Fusion (EGFR, TYRO3 Human)
   

   Expression

   Mammalian

   Promoter

   EF1-a

   Available Since

   Nov. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. JDW 832 (pDONR221-V5-mTagBFP2-KRAS4A-G12D)

   Plasmid

   #156404

   Purpose

   Gateway middle entry clone encoding V5-tagged mTagBFP2-fused to human KRAS4A with G12D mutation, includes a stop codon

   Depositor

   Joshua Wythe

   Article

   Fish et al Circ Res. 2020 Jun 17. doi: 10.1161/CIRC

   Insert

   human mutant KRAS4A-G12D (KRAS Human)
   

   Use

   Gateway cloning

   Tags

   mTagBFP2

   Mutation

   mutant KRAS4A-G12D

   Available Since

   Aug. 18, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. (114) pcDNA3.1-GFP-Flag-JunB-EPEA

   Plasmid

   #160743

   Purpose

   Expresses a GFP tagged JunB with Flag and EPEA tags.

   Depositor

   Christina Woo

   Article

   Ramirez et al ACS Chem Biol. 2020 Apr 17;15(4):1059-10

   Insert

   GFP-Flag-JunB-EPEA (JUN Human)
   

   Tags

   EPEA, Flag, and GFP

   Expression

   Mammalian

   Promoter

   T7/CMV

   Available Since

   May 18, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. YES1 gRNA (BRDN0001148961)

   Plasmid

   #77967

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human YES1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   YES1 (YES1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. YES1 gRNA (BRDN0001145317)

   Plasmid

   #77965

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human YES1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   YES1 (YES1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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10. YES1 gRNA (BRDN0001487120)

    Plasmid

    #77966

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human YES1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    YES1 (YES1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. CMV-LUC2CP/intron/ARE

    Plasmid

    #62858

    Purpose

    splicing reporter (with intron) with elements to shorten the half-life of the luciferase protein as well as the luciferase mRNA.

    Depositor

    Gideon Dreyfuss

    Article

    Younis et al Mol Cell Biol. 2010 Apr;30(7):1718-28. d

    Insert

    Luciferase
    

    Use

    Luciferase

    Expression

    Mammalian

    Mutation

    insertion of chimeric intron at nueotide poclsiti…

    Promoter

    CMV

    Available Since

    April 3, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCMV14_NHP2L1(15.5kD)

    Plasmid

    #73065

    Purpose

    expression clone for human NHP2L1 (15.5kD) with C-terminal 3xFLAG-tag

    Depositor

    Stefan Stamm

    Article

    Falaleeva et al Proc Natl Acad Sci U S A. 2016 Mar 22;11

    Insert

    NHP2L1 (15.5kD) (SNU13 Human)
    

    Tags

    3xFLAG

    Expression

    Mammalian

    Available Since

    Dec. 7, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3.1.D2-NP

    Plasmid

    #134366

    Purpose

    Nanoluc complementation assay. Expression of dopamine receptor D2 fused at C terminus with Natural peptide (NP) of NanoLuc. Addition of the signal sequence and Flag epitope at N terminus of D2.

    Depositor

    Julien Hanson

    Article

    Laschet et al J Biol Chem. 2019 Mar 15;294(11):4079-40

    Insert

    D2-NP (DRD2 Human)
    

    Tags

    Flag, natural peptide of nanoluciferase, and sign…

    Expression

    Bacterial and Mammalian

    Promoter

    T7

    Available Since

    July 22, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. mP58.dJ1-pCDNA3

    Plasmid

    #21884

    Depositor

    David Ron

    Article

    Oyadomari et al Cell. 2006 Aug 25. 126(4):727-39.

    Insert

    P58 (Dnajc3 Mouse)
    

    Expression

    Mammalian

    Mutation

    DnaJ domain deleted from C-term

    Available Since

    Sept. 14, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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15. PB-CAG-ChR2-YFP

    Plasmid

    #204345

    Purpose

    PiggyBac transposon vector suitable for inserting the ChR2-YFP optogenetic actuator driven by the ubiquitous CAG promoter into the genome of mammalian cell lines.

    Depositor

    Ivo Lieberam

    Article

    Harley et al Cell Rep. 2023 Dec 26;42(12):113509. doi

    Insert

    ChR2-YFP
    

    Tags

    Yellow fluorescent protein

    Expression

    Mammalian

    Mutation

    C-terminus (aa315-737) is deleted - PMID: 1461559…

    Promoter

    CAG

    Available Since

    Oct. 18, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGART-2XStrep

    Plasmid

    #125681

    Purpose

    expresses human GART protein with a C-terminal 2XStrep affinity tag

    Depositor

    Stephen Benkovic

    Article

    Liu et al J Proteome Res. 2019 May 3;18(5):2078-20

    Insert

    GART (GART Human)
    

    Tags

    2X Strep-Tag II

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Sept. 13, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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17. pcDNA5/FRT/TO-DDX54-FLAG/HA

    Plasmid

    #97062

    Purpose

    Expresses DDX54-FLAG/HA (C-terminal tagged) in mammalian cells

    Depositor

    Markus Landthaler

    Article

    Milek et al Genome Res. 2017 Aug;27(8):1344-1359. do

    Insert

    DDX54 (DDX54 Human)
    

    Tags

    FLAG/HA

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    July 17, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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18. pBabe puro H-Ras 61L

    Plasmid

    #13485

    Depositor

    Channing Der

    Article

    Khosravi-Far et al Mol Cell Biol. 1996 Jul . 16(7):3923-33.

    Insert

    HRas 61L (HRAS Human)
    

    Use

    Retroviral

    Expression

    Mammalian

    Mutation

    61L

    Available Since

    Dec. 20, 2006

    Availability

    Academic Institutions and Nonprofits only

19. pcDNA3.1.H1-NP

    Plasmid

    #134367

    Purpose

    Nanoluc complementation assay. Expression of histamine receptor H1 fused at C termimus with Natural peptide (NP) of NanoLuc. Addition of the Flag epitope at N terminus of H1 receptor.

    Depositor

    Julien Hanson

    Article

    Laschet et al J Biol Chem. 2019 Mar 15;294(11):4079-40

    Insert

    H1-NP (HRH1 Human)
    

    Tags

    Flag and natural peptide of nanoluciferase

    Expression

    Bacterial and Mammalian

    Promoter

    T7

    Available Since

    July 22, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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20. pET28-MRPP3-His

    Plasmid

    #67866

    Purpose

    bacterial expression of PRORP (KIAA0391), full coding sequence (mitoch. form) + C-term. His tag

    Depositor

    Walter Rossmanith

    Article

    Vilardo et al Nucleic Acids Res. 2012 Dec;40(22):11583

    Insert

    MRPP3 (KIAA0391 Human)
    

    Tags

    His

    Expression

    Bacterial

    Mutation

    Amino acid 46 of recombinant MRPP3 is preceded by…

    Promoter

    T7

    Available Since

    Aug. 14, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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