We narrowed to 8,683 results for: sgRNA

1. pPN187

   Plasmid

   #91574

   Purpose

   Express sgRNA targeting human AKT3

   Depositor

   Lindy Barrett

   Article

   Hazelbaker et al Stem Cell Reports. 2017 Oct 10;9(4):1315

   Insert

   AKT3 (AKT3 Human)
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   Oct. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. API5-CRISPR

   Plasmid

   #157664

   Purpose

   Expresses Cas9 and sgRNA targeting API5

   Depositor

   Byung Il Lee

   Article

   Bong et al Nucleic Acids Res. 2020 Jun 19;48(11):63

   Insert

   Apoptosis inhibitor 5 (API5 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Aug. 20, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCW57.1 tTA SDHA

   Plasmid

   #177976

   Purpose

   All-in-one dox-repressible expression of cDNA

   Depositor

   Jessica Spinelli, David Sabatini

   Article

   Spinelli et al Science. 2021 Dec 3;374(6572):1227-1237.

   Insert

   SDHA (SDHA Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Silent point mutations to SDHA sgRNA target

   Available Since

   Dec. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. LentiCRISPR v2-sgAMPK alpha1 clone3

   Plasmid

   #162121

   Purpose

   Lentiviral sgRNA plasmid targeting human AMPK alpha1

   Depositor

   Boyi Gan

   Article

   Lee et al Nat Cell Biol. 2020 Feb;22(2):225-234. d

   Insert

   sgAMPK alpha1 (PRKAA1 Human)
   

   Use

   Lentiviral

   Available Since

   Jan. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. ARB365

   Plasmid

   #124048

   Purpose

   Encodes pEF1a driving expression of TET3G P2A iRFP713, pEF1a expressing sadCas9 fused to mRuby2 P2A mRuby2, and an sgRNA targeting pUAS expressing mAzamiGreen in a PiggyBac destination vector

   Depositor

   Hana El-Samad

   Article

   Fonseca et al ACS Synth Biol. 2019 Nov 15;8(11):2593-2

   Insert

   PB_pEF1a-tet3G-P2A-iRFP713_pEF1a-sadCAS9::mRuby2-P2A-mRuby2-SV40PA_mu6-sgUAS_pUAS-NLS::mAzamiGreen-rgPA
   

   Expression

   Mammalian

   Available Since

   Dec. 13, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAWp28-v1 scaffold

   Plasmid

   #157976

   Purpose

   pBT264-U6p-{2xBbsI}-v1 sgRNA scaffold-{MfeI} Note: This plasmid is unstable. Screen multiple colonies to identify full length clones.

   Depositor

   Alan Siu Lun Wong

   Article

   Zhou et al Cell Rep. 2020 Aug 11;32(6):108020. doi:

   Type

   Empty backbone

   Available Since

   May 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAWp102-v2 scaffold

   Plasmid

   #157978

   Purpose

   pBT264-mutmU6p-{2xBbsI}-v2 sgRNA scaffold-{MfeI}

   Depositor

   Alan Siu Lun Wong

   Article

   Zhou et al Cell Rep. 2020 Aug 11;32(6):108020. doi:

   Type

   Empty backbone

   Available Since

   Nov. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAVsc.U6-sgGTTG.CMV/CB-Gluc

   Plasmid

   #121512

   Purpose

   Expresses sgRNA targeting the intron in the MADM alleles (GT and TG).

   Depositor

   Guangping Gao

   Article

   Wang et al Nat Biotechnol. 2018 Oct;36(9):839-842.

   Insert

   sgGTTG
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   July 22, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pENTR221-H1-sgGFP1-7SK-sgCas9

   Plasmid

   #87908

   Purpose

   multiple sgRNA

   Depositor

   Nicole Déglon

   Article

   Merienne et al Cell Rep. 2017 Sep 19;20(12):2980-2991.

   Insert

   sgGFP1, sgCas9
   

   Use

   Gateway entry vector

   Promoter

   H1, 7SK

   Available Since

   Sept. 19, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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10. pGL3-U6-pegRNA_HOXD13_CtoT-EGFP

    Plasmid

    #159792

    Purpose

    S. pyogenes pegRNA for C to T mutation at the HOXD13 site of mouse cells using prime editing

    Depositor

    Xiaolong Wang

    Article

    Liu et al Cell Discov. 2020 Apr 28;6:27. doi: 10.1

    Insert

    spacer of pegRNA_HOXD13_CtoT targeting HOXD13 gene (HOXD13 Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 20, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pGL3-U6-pegRNA_HOXD13_CtoG-EGFP

    Plasmid

    #159791

    Purpose

    S. pyogenes pegRNA for C to G mutation at the HOXD13 site of mouse cells using prime editing

    Depositor

    Xiaolong Wang

    Article

    Liu et al Cell Discov. 2020 Apr 28;6:27. doi: 10.1

    Insert

    spacer of pegRNA_HOXD13_CtoG targeting HOXD13 gene (HOXD13 Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 20, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLenti-Puro-sgSIK3-A

    Plasmid

    #138682

    Purpose

    Expresses a mouse SIK3-targeting sgRNA and Cas9

    Depositor

    Reuben Shaw

    Article

    Hollstein et al Cancer Discov. 2019 Nov;9(11):1606-1627.

    Insert

    sgSIK3 mouse (Sik3 Mouse)
    

    Use

    Lentiviral

    Promoter

    hU6

    Available Since

    Feb. 26, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLenti-Puro-sgSIK3-C

    Plasmid

    #138683

    Purpose

    Expresses a mouse SIK3-targeting sgRNA and Cas9

    Depositor

    Reuben Shaw

    Article

    Hollstein et al Cancer Discov. 2019 Nov;9(11):1606-1627.

    Insert

    sgSIK3 mouse (Sik3 Mouse)
    

    Use

    Lentiviral

    Promoter

    hU6

    Available Since

    Feb. 20, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. pTBL649 CHYRON2 integration construct

    Plasmid

    #126446

    Purpose

    To integrate the CHYRON2 locus at AAVS1 in human cells.

    Depositor

    Chang Liu

    Article

    Loveless et al Nat Chem Biol. 2021 Jun;17(6):739-747. d

    Inserts

    pU6-CHYRON2 hgRNA
    pCMV-puro
    

    Expression

    Mammalian

    Mutation

    The SpCas9 sgRNA constant region is mutated to ma…

    Promoter

    CMV and human U6

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLentiCRISPR V2 sgYME1L1 sg1

    Plasmid

    #244867

    Purpose

    Knockout of human YME1L1

    Depositor

    Alexis Jourdain

    Article

    Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

    Insert

    YME1L1 sgRNA (YME1L1 Human)
    

    Use

    CRISPR and Lentiviral

    Promoter

    U6

    Available Since

    Nov. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. LLP1017

    Plasmid

    #239939

    Purpose

    CaMV 35S driving the expression of dCas9-ZAT10(1x)

    Depositor

    Ryan Lister

    Article

    Khan et al Nat Biotechnol. 2025 Mar;43(3):416-430.

    Insert

    CaMV 35S::dCas9-ZAT10(1x)
    

    Use

    CRISPR and Synthetic Biology

    Mutation

    N/A

    Available Since

    Oct. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. LLP1023

    Plasmid

    #239945

    Purpose

    CaMV 35S driving the expression of dCas9

    Depositor

    Ryan Lister

    Article

    Khan et al Nat Biotechnol. 2025 Mar;43(3):416-430.

    Insert

    CaMV 35S::dCas9
    

    Use

    CRISPR and Synthetic Biology

    Mutation

    N/A

    Available Since

    Oct. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. LLP1019

    Plasmid

    #239941

    Purpose

    CaMV 35S driving the expression of dCas9-ZAT10(1x)

    Depositor

    Ryan Lister

    Article

    Khan et al Nat Biotechnol. 2025 Mar;43(3):416-430.

    Insert

    CaMV 35S::dCas9-ZAT10(1x)
    

    Use

    CRISPR and Synthetic Biology

    Expression

    Plant

    Mutation

    N/A

    Available Since

    Oct. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLentiCRISPR_blast_FAM136A_sg2

    Plasmid

    #244876

    Purpose

    Knockout of human FAM136A

    Depositor

    Alexis Jourdain

    Article

    Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

    Insert

    FAM136A sgRNA (FAM136A Human)
    

    Use

    CRISPR and Lentiviral

    Promoter

    U6

    Available Since

    Oct. 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLentiCRISPR_puro_FAM136A_sg1

    Plasmid

    #244877

    Purpose

    Knockout of human FAM136A

    Depositor

    Alexis Jourdain

    Article

    Harhai et al Cell Rep. 2025 Jul 25;44(8):116069. doi:

    Insert

    FAM136A sgRNA (FAM136A Human)
    

    Use

    CRISPR and Lentiviral

    Promoter

    U6

    Available Since

    Oct. 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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