We narrowed to 2,838 results for: 52963

1. lentiGuide-Puro

   Plasmid

   #52963

   Purpose

   Expresses S. pyogenes CRISPR chimeric RNA element with customizable sgRNA from U6 promoter and puromycin resistance from EF-1a promoter. 3rd generation lentiviral backbone.

   Depositor

   Feng Zhang

   Publication

   Sanjana et al Nat Methods. 2014 Aug;11(8):783-4. doi:

   Inserts

   S. pyogenes sgRNA cassette
   Puromycin resistance
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   Ef1-a and hU6

   Available since

   May 8, 2014

   Availability

   Academic Institutions and Nonprofits only

   Cited by

   884 Articles

   

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These results may also be relevant.

1. EIF2AK3 gRNA (BRDN0001145848)

   Plasmid

   #77166

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EIF2AK3

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EIF2AK3 (EIF2AK3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. lentiGuide-Puro PRMT5-CRISPRi

   Plasmid

   #164637

   Purpose

   lentiGuide-Puro backbone with cloned target sequence for human PRMT5. The insert is: 5´- CACCGAGCCGCGTGTCCAGCGGGA-3. sgRNA achieves a downregulation of PRMT5 in combination with dCAS9-KRAB-MCP2

   Depositor

   Günter Schneider

   Insert

   target guide sequence PRMT5 inhibition (PRMT5 Human)
   

   Use

   CRISPR and Lentiviral; Interference

   Expression

   Mammalian

   Promoter

   U6 and EF1A

   Available since

   May 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. non-targeting control gRNA (BRDN0001149423)

   Plasmid

   #80255

   Purpose

   3rd generation lentiviral gRNA plasmid, non-targeting control gRNA

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   Non-targeting control gRNA
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   Aug. 30, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. CDK2 gRNA (BRDN0001148950)

   Plasmid

   #77193

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK2

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK2 (CDK2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. CDK2 gRNA (BRDN0001148866)

   Plasmid

   #77191

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK2

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK2 (CDK2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. STK11 gRNA (BRDN0001147319)

   Plasmid

   #75914

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human STK11

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   STK11 (STK11 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. BRD4 gRNA (BRDN0001147232)

   Plasmid

   #77345

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human BRD4

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   BRD4 (BRD4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. BRD4 gRNA (BRDN0001145474)

   Plasmid

   #77347

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human BRD4

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   BRD4 (BRD4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. RAF1 gRNA (BRDN0001148013)

   Plasmid

   #76706

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human RAF1

   Depositor

   John Doench, David Root

   Publication

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   RAF1 (RAF1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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10. RAF1 gRNA (BRDN0001145852)

    Plasmid

    #76707

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human RAF1

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    RAF1 (RAF1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. MERTK gRNA (BRDN0001145505)

    Plasmid

    #76444

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MERTK

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MERTK (MERTK Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. MET gRNA (BRDN0001145767)

    Plasmid

    #76060

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MET

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MET (MET Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. MET gRNA (BRDN0001147542)

    Plasmid

    #76062

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MET

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MET (MET Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. MET gRNA (BRDN0001147257)

    Plasmid

    #76063

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MET

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MET (MET Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. EIF2AK2 gRNA (BRDN0001146342)

    Plasmid

    #75637

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EIF2AK2

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EIF2AK2 (EIF2AK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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16. AKT1 gRNA (BRDN0001149266)

    Plasmid

    #75501

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AKT1

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    AKT1 (AKT1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. PRKDC gRNA (BRDN0001145772)

    Plasmid

    #77862

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PRKDC

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PRKDC (PRKDC Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 12, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. MAPK3 gRNA (BRDN0001147876)

    Plasmid

    #75967

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAPK3

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAPK3 (MAPK3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. MAPK1 gRNA (BRDN0001149093)

    Plasmid

    #77788

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAPK1

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAPK1 (MAPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. ERBB2 gRNA (BRDN0001146057)

    Plasmid

    #76376

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ERBB2

    Depositor

    John Doench, David Root

    Publication

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ERBB2 (ERBB2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge