We narrowed to 407 results for: SAM activators

1. pAAV-CAG-mCherry-Tandem-PSAM4-GlyR

   Plasmid

   #208361

   Purpose

   Expression of the inhibitory chemogenetic tool PSAM4-GlyR and mCherry reporter. Application of ultrapotent agonists induces neuronal silencing.

   Depositor

   David Bennett

   Article

   Perez-Sanchez et al Sci Transl Med. 2023 Oct 4;15(716):eadh3

   Insert

   mCherry-TANDEM-PSAM4-GlyR
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   Oct. 13, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. rAAV-syn::FLEX-rev::PSAML141F,Y115F:5HT3HC-IRES-GFP

   Plasmid

   #32477

   Purpose

   Cre-dependent expression of PSAM-5HT3 HC (L141F,Y115F) neuronal activator, with IRES-EGFP marker

   Depositor

   Scott Sternson

   Article

   Magnus et al Science. 2011 Sep 2;333(6047):1292-6.

   Insert

   PSAML141F,Y115F-5HT3HC
   

   Use

   AAV and Cre/Lox; Adeno-associated virus, flex swi…

   Tags

   IRES-EGFP

   Promoter

   Synapsin

   Available Since

   Jan. 12, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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3. rAAV-syn::FLEX-rev::PSAMQ79G,Q139G:5HT3HC-IRES-GFP

   Plasmid

   #32475

   Purpose

   Cre-dependent expression of PSAM-5HT3 HC (Q79G,Q139G) neuronal activator, with IRES-EGFP marker

   Depositor

   Scott Sternson

   Article

   Magnus et al Science. 2011 Sep 2;333(6047):1292-6.

   Insert

   PSAMQ79G,Q139G-5HT3HC
   

   Use

   AAV and Cre/Lox; Adeno-associated virus, flex swi…

   Tags

   IRES-EGFP

   Promoter

   Synapsin

   Available Since

   Dec. 12, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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4. pYJ15-PB-U6-Nkx6.1-acti-gRNA1

   Plasmid

   #131059

   Purpose

   Activation of NKX6.1 via SAM system

   Depositor

   Xiaojun Lian

   Insert

   NKX6.1 activation gRNA1 (NKX6-1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Oct. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pYJ16-PB-U6-Nkx6.1-acti-gRNA2

   Plasmid

   #131060

   Purpose

   Activation of NKX6.1 via SAM system

   Depositor

   Xiaojun Lian

   Insert

   NKX6.1 activation gRNA2 (NKX6-1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Oct. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pYJ17-PB-U6-Nkx6.1-acti-gRNA3

   Plasmid

   #131061

   Purpose

   Activation of Mafa via SAM system

   Depositor

   Xiaojun Lian

   Insert

   NKX6.1 activation gRNA3 (NKX6-1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Oct. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pYJ12-PB-U6-ND1-acti-gRNA1

   Plasmid

   #131056

   Purpose

   Activation of NeuroD1 via SAM system

   Depositor

   Xiaojun Lian

   Insert

   NeuroD1 activation gRNA1 (NEUROD1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Oct. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pYJ13-PB-U6-ND1-acti-gRNA2

   Plasmid

   #131057

   Purpose

   Activation of NeuroD1 via SAM system

   Depositor

   Xiaojun Lian

   Insert

   NeuroD1 activation gRNA2 (NEUROD1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Oct. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pYJ14-PB-U6-ND1-acti-gRNA3

   Plasmid

   #131058

   Purpose

   Activation of NeuroD1 via SAM system

   Depositor

   Xiaojun Lian

   Insert

   NeuroD1 activation gRNA3 (NEUROD1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Oct. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pYJ23-lenti-MS2-U6-NKX6.1-acti-gRNA1

    Plasmid

    #131067

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA1 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pYJ24-lenti-MS2-U6-NKX6.1-acti-gRNA2

    Plasmid

    #131068

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA2 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pYJ25-lenti-MS2-U6-NKX6.1-acti-gRNA3

    Plasmid

    #131069

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA3 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. gRNA-10Xcapture-PuroR

    Plasmid

    #211496

    Purpose

    Plasmid for the expression of SAM-compatible gRNA for CRISPRa with capturer sequence for 10X Genomics sequencing

    Depositor

    Antonella Fidanza, Lesley Forrester

    Article

    Petazzi et al Elife. 2024 Dec 23;13:RP94884. doi: 10.7

    Inserts

    U6-gRNA
    Ef1a-PuroR
    

    Use

    CRISPR, Lentiviral, and Synthetic Biology

    Expression

    Mammalian

    Promoter

    EF1a and U6

    Available Since

    Dec. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pYJ29-lenti-U6-SOX17-acti-gRNA-DsRed

    Plasmid

    #131072

    Purpose

    Activation of SOX17 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    SOX17 activation gRNA (SOX17 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pYJ18-PB-U6-Mafa-acti-gRNA1

    Plasmid

    #131062

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA1 (MAFA Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pYJ19-PB-U6-Mafa-acti-gRNA2

    Plasmid

    #131063

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA2 (MAFA Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pYJ20-PB-U6-Mafa-acti-gRNA3

    Plasmid

    #131064

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA3 (MAFA Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. CROPSeq-PP7-p65-HSF

    Plasmid

    #196719

    Purpose

    CROP-Seq library plasmid for CRISPR-A with SAM system (p65-HSF1 activator recruited to PP7 binding loops in the tracrRNA of the guide).

    Depositor

    Bernhard Schmierer

    Type

    Empty backbone

    Use

    CRISPR and Lentiviral

    Tags

    Nucleoplasmin NLS and SV40 NLS

    Available Since

    April 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pYJ30-lenti-U6-MAFA-acti-gRNA1-MS2

    Plasmid

    #131073

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA1 (MAFA Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pYJ31-lenti-U6-MAFA-acti-gRNA2-MS2

    Plasmid

    #131074

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA2 (MAFA Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge