We narrowed to 19 results for: LIC

1. Mouse Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187081

   Purpose

   Library targeting 2,989 mouse metabolic genes for activation of gene expression.

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   Lentiviral

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

2. Human CRISPR Metabolic Gene Knockout Library

   Pooled Library

   #110066

   Purpose

   Targets 2,981 human metabolic genes with 29,790 guide RNAs. The library contains ~10 gRNAs per gene.

   Depositor

   David Sabatini

   Article

   Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

   Use

   Lentiviral

   Available Since

   May 4, 2018

   Availability

   Academic Institutions and Nonprofits only

3. Human Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187080

   Purpose

   Library targeting 2,989 human metabolic genes for activation of gene expression.

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

4. Splicing-targeting CRISPR-Cas9 library for human lncRNAs

   Pooled Library

   #119977

   Purpose

   Designed for genomic deletion screening of functional lncRNAs by targeting their splice sites.

   Depositor

   Wensheng Wei

   Article

   Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   March 27, 2019

   Availability

   Academic Institutions and Nonprofits only

5. LV2btCRISPRko.v1

   Pooled Library

   #213927

   Purpose

   Uses lentivirus to deliver the library into hard-to-transduce cells

   Depositor

   Wenfang Spring Tan

   Article

   Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

6. PBbtCRISPRko.v1

   Pooled Library

   #213928

   Purpose

   Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

   Depositor

   Wenfang Spring Tan

   Article

   Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

7. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Knockout library targeting mouse metabolic genes.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available Since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

8. CRASP-Seq Gene KO v1 empty

   Pooled Library

   #232069

   Purpose

   Knockout library for use in CRASP-Seq experiments. Provides a flexible platform for studying splicing regulation.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

9. CRASP-Seq BE Tiling v1 empty

   Pooled Library

   #232070

   Purpose

   Tiling library to conduct CRASP-Seq experiments combined with high-throughput base editing for precise and scalable investigations into protein regions that affect splicing regulation.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 28, 2025

   Availability

   Academic Institutions and Nonprofits only

10. DDR_MKOv4

    Pooled Library

    #140219

    Purpose

    Knockout library targeting human DNA damage response and DNA repair genes.

    Depositor

    Junjie Chen

    Article

    Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Inzolia library in pRDA_550

    Pooled Library

    #209552

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

12. Inzolia library in pRDA_052

    Pooled Library

    #209551

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

13. SPLINTR mCHERRY v1

    Pooled Library

    #179775

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

14. SPLINTR GFP v1

    Pooled Library

    #179774

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

15. SPLINTR BFP v1

    Pooled Library

    #179776

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

16. CRASP-Seq CBC Backbone

    Pooled Library

    #232068

    Purpose

    The CRASP-Seq backbone is designed to accommodate the cloning of diverse gRNA libraries. It includes a cell barcode (CBC), which enhances its functionality by enabling library preparation.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

17. BARBEKO sgRNA library

    Pooled Library

    #174163

    Purpose

    Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.

    Depositor

    Wensheng Wei

    Article

    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

18. Human Paralog Knockout Library (pgPEN)

    Pooled Library

    #171172

    Purpose

    Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs.

    Depositor

    Alice Berger

    Article

    Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

    Expression

    Mammalian

    Species

    Homo sapiens and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

19. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    Targets 3' splice sites with paired gRNAs. Induces skipping of poison cassette exons and matching upstream constitutive exons. Compare loss of a constitutive coding exon with loss of a poison exon.

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only