We narrowed to 16 results for: LIC

1. Human CRISPR Metabolic Gene Knockout Library

   Pooled Library

   #110066

   Purpose

   Encodes gRNAs for targeting metabolic genes in CRISPR screens.

   Depositor

   David Sabatini

   Article

   Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

   Use

   Lentiviral

   Available since

   May 4, 2018

   Availability

   Academic Institutions and Nonprofits only

2. Human Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187080

   Purpose

   Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

3. Mouse Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187081

   Purpose

   Lentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   Lentiviral

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

4. Splicing-targeting CRISPR-Cas9 library for human lncRNAs

   Pooled Library

   #119977

   Purpose

   The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

   Depositor

   Wensheng Wei

   Article

   Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   March 27, 2019

   Availability

   Academic Institutions and Nonprofits only

5. LV2btCRISPRko.v1

   Pooled Library

   #213927

   Purpose

   Uses lentivirus to deliver the library into hard-to-transduce cells

   Depositor

   Wenfang Spring Tan

   Article

   Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

6. PBbtCRISPRko.v1

   Pooled Library

   #213928

   Purpose

   Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

   Depositor

   Wenfang Spring Tan

   Article

   Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

7. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Mouse metabolism knockout library

   Pooled Library

   #160129

   Purpose

   CRISPR library targets mouse metabolic genes

   Depositor

   Kivanc Birsoy

   Article

   Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 10, 2020

   Availability

   Academic Institutions and Nonprofits only

9. DDR_MKOv4

   Pooled Library

   #140219

   Purpose

   CRISPR DNA damage response library

   Depositor

   Junjie Chen

   Article

   Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 20, 2021

   Availability

   Academic Institutions and Nonprofits only

10. Human Paralog Knockout Library (pgPEN)

    Pooled Library

    #171172

    Purpose

    CRISPR library targets human duplicate paralog gene pairs

    Depositor

    Alice Berger

    Article

    Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

    Expression

    Mammalian

    Species

    Homo sapiens and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Inzolia library in pRDA_052

    Pooled Library

    #209551

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

12. Inzolia library in pRDA_550

    Pooled Library

    #209552

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

13. SPLINTR mCHERRY v1

    Pooled Library

    #179775

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

14. SPLINTR BFP v1

    Pooled Library

    #179776

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

15. SPLINTR GFP v1

    Pooled Library

    #179774

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

16. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only