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Human Lentiviral sgRNA Library - Kinases

Pooled Library

#51044

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Ma-PylRS-lib1

Pooled Library

#224585

Purpose

Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

Depositor

Ryan Mehl

Article

Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

Expression

Bacterial

Species

Methanomethylophilus alvus

Available Since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only
Human genome-wide lentiviral CRISPR gRNA library version 1

Pooled Library

#67989

Purpose

Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Depositor

Kosuke Yusa

Article

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Species

Homo sapiens, Mus musculus, and Synthetic

Use

CRISPR and Lentiviral

Available Since

Oct. 14, 2016

Availability

Academic Institutions and Nonprofits only
Watermelon

Pooled Library

#155257

Purpose

Lineage tracing library

Depositor

Joan Brugge, Aviv Regev

Article

Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

Expression

Mammalian

Use

Lentiviral

Available Since

Oct. 15, 2021

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Control

Pooled Library

#51048

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiCRISPRv2

Pooled Library

#73179

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
LARRYv2-EGFP library 1

Pooled Library

#233215

Purpose

Barcoding pooled library

Depositor

Alejo Rodriguez-Fraticelli

Article

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

Species

Synthetic

Use

Lentiviral

Available Since

March 6, 2025

Availability

Academic Institutions and Nonprofits only
Bison sgRNA library

Pooled Library

#169942

Purpose

Knockout library targeting ubiquitin ligases, deubiquitinases, and control genes.

Depositor

Benjamin Ebert

Article

Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

Use

Lentiviral

Available Since

Sept. 9, 2021

Availability

Academic Institutions and Nonprofits only
Human Kinase Domain-Focused CRISPR Knockout Library

Pooled Library

#117725

Purpose

Designed for genomic deletion screening of protein kinases by targeting the kinase domains.

Depositor

Christopher Vakoc

Article

Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Human Epigenetic Knockout Library

Pooled Library

#162256

Purpose

Knockout library that targets human epigenetic genes.

Depositor

Kivanc Birsoy

Article

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Nov. 17, 2020

Availability

Academic Institutions and Nonprofits only
Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

Pooled Library

#1000000114

Purpose

Genome-wide CRISPR gRNA pooled library for inhibition of human genes

Depositor

John Doench, David Root

Available Since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

Pooled Library

#161769

Purpose

Tet-inducible inhibition library targeting the yeast genome with barcode linked guide RNAs.

Depositor

Nicholas Ingolia

Article

McGlincy et al BMC Genomics. 2021 Mar 23;22(1):205. doi

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available Since

Nov. 30, 2021

Availability

Academic Institutions and Nonprofits only
TCR Rapid Assembly for Functional Testing (TCRAFT)

Pooled Library

#1000000264

Depositor

Michael Birnbaum

Available Since

Aug. 12, 2025

Availability

Academic Institutions and Nonprofits only
Humagne Set D

Pooled Library

#172651

Purpose

Set D contains best-ranked guides 2 and 3.

Depositor

John Doench, David Root

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available Since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
MORF Library Kit with GFP and mCherry controls

Pooled Library

#1000000218

Depositor

Feng Zhang

Available Since

March 24, 2023

Availability

Academic Institutions and Nonprofits only
Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Targets 2,981 human metabolic genes with 29,790 guide RNAs. The library contains ~10 gRNAs per gene.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available Since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
psgRNA_EcoWG1

Pooled Library

#131625

Purpose

Bacterial inhibition library targeting every small RNA and ORF of the E. coli MG1655 genome. This library has higher inhibition efficiency than the psgRNA library.

Depositor

David Bikard

Article

Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

Expression

Bacterial

Species

Escherichia coli

Use

CRISPR

Available Since

May 12, 2020

Availability

Academic Institutions and Nonprofits only
lentiCRISPRv2_ISG

Pooled Library

#125753

Purpose

Knockout library targeting a set of human interferon-stimulated genes (ISGs).

Depositor

Michael Emerman, Molly OhAinle

Article

Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

May 7, 2020

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 399 results

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More Filters

399 results

Human Lentiviral sgRNA Library - Kinases

Ma-PylRS-lib1

Human genome-wide lentiviral CRISPR gRNA library version 1

Watermelon

Human Lentiviral sgRNA Library - Control

Human sgRNA library Brunello in lentiGuide-Puro

Human sgRNA library Brunello in lentiCRISPRv2

LARRYv2-EGFP library 1

Bison sgRNA library

Human Kinase Domain-Focused CRISPR Knockout Library

Mouse sgRNA library Brie in lentiGuide-Puro

Human Epigenetic Knockout Library

Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

TCR Rapid Assembly for Functional Testing (TCRAFT)

Humagne Set D

MORF Library Kit with GFP and mCherry controls

Human CRISPR Metabolic Gene Knockout Library

psgRNA_EcoWG1

lentiCRISPRv2_ISG

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