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Jonathan Weissman Lab Plasmids


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Title Authors Publication
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044.
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9.
Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Jan CH, Williams CC, Weissman JS Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6.
Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Williams CC, Jan CH, Weissman JS Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522.
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760.
Next-generation libraries for robust RNA interference-based genome-wide screens. Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3384-91. doi: 10.1073/pnas.1508821112. Epub 2015 Jun 15.
Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Kampmann M, Bassik MC, Weissman JS Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2317-26. doi: 10.1073/pnas.1307002110. Epub 2013 Jun 5.
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Adamson B, Norman TM, Jost M, Cho MY, Nunez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048.
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, Weissman JS, Lim DA Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111.
ID Plasmid Gene/Insert Vector Type Publication Hidden Extra Search Info  
46910pHR-SFFV-dCas9-BFPdCas9-BFP fusion (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human expression vector containing SFFV promoter, dCas9 that is fused to 2x NLS and tagBFP pHR Add to Cart
46911pHR-SFFV-dCas9-BFP-KRABdCas9-BFP-KRAB fusion (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human expression vector containing SFFV promoter, dCas9 that is fused to 2x NLS, tagBFP and a KRAB domain pHR Add to Cart
46912pMSCV-LTR-dCas9-VP64-BFPdCas9-VP64-BFP fusion (Homo sapiens), Puromycin resistanceMammalian Expression, Retroviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human expression vector containing MSCV LTR promoter, dCas9 that is fused to 2x NLS, VP64 and tagBFP MSCV-puro Add to Cart
46913pMSCV-LTR-dCas9-p65AD-BFPdCas9-p65AD-BFP fusion (Homo sapiens), Puromycin resistanceMammalian Expression, Retroviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human expression vector containing MSCV LTR promoter, dCas9 that is fused to 2x NLS, p65 activation domain and tagBFP MSCV-puro Add to Cart
46914pU6-sgGFP-NT1sgGFP-NT1Mammalian Expression, Lentiviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human pSico-based U6 vector containing murine U6 promoter and sgRNA targeting GFP (NT1) pSICO derivative Add to Cart
46915pU6-sgGAL4-1sgGAL4-1, Puromycin resistance and mCherryMammalian Expression, Lentiviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human pSico-based U6 vector containing murine U6 promoter and sgRNA targeting GAL4 UAS promoter pSICO derivative Add to Cart
46916pU6-sgGAL4-4sgGAL4-4, Puromycin resistance and mCherryMammalian Expression, Lentiviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human pSico-based U6 vector containing murine U6 promoter and sgRNA targeting GAL4 UAS promoter (negative control) pSICO derivative Add to Cart
46917pU6-sgCXCR4-2sgCXCR4 -2 (Homo sapiens), Puromycin resistance and mCherryMammalian Expression, Lentiviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human pSico-based U6 vector containing murine U6 promoter and sgRNA targeting endogenous CXCR4 gene pSICO derivative CXCR4 CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS Add to Cart
46918pU6-sgCD71-2sgCD71 -2 (Homo sapiens), Puromycin resistance and mCherryMammalian Expression, Lentiviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Human pSico-based U6 vector containing murine U6 promoter and sgRNA targeting endogenous CD71 gene pSICO derivative TFRC CD71, IMD46, T9, TFR, TFR1, TR, TRFR, p90 Add to Cart
46919pMLS-SV40-EGFPGFPMammalian Expression, Retroviral, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Target EGFP gene that is stably integrated into HEK293 genome MSCV-puro Add to Cart
46920pTDH3-dCas9dCas9Yeast Expression, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Yeast CEN/ARS vector (Leu2) that contains dCas9 fused to NLS controlled by TDH3 promoter pJED103 Add to Cart
46921pTDH3-dCas9-Mxi1dCas9-Mxi1Yeast Expression, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Yeast CEN/ARS vector (Leu2) that contains dCas9 fused to NLS and Mxi1 domain controlled by TDH3 promoter pJED103 Add to Cart
46922pSNR52-sgTEF1sgTEF1 promoter (Saccharomyces cerevisiae)Yeast Expression, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Yeast CEN/ARS vector (Ura3) that contains sgRNA controlled by SNR 52 promoter, targeting endogenous TEF1 promoter AH057 TEF1 YPR080W Add to Cart
46923pSNR52-sgTETsgRNA targeting endogenous TRE elements of pTET07 promoter (Saccharomyces cerevisiae)Yeast Expression, CRISPRCRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes. Cell. 2013 Jul 9. pii: S0092-8674(13)00826-X. doi: 10.1016/j.cell.2013.06.044. Yeast CEN/ARS vector (Ura3) that contains sgRNA controlled by SNR 52 promoter, targeting endogenous TRE elements of pTET07 promoter AH057 Add to Cart
60954pHR-SFFV-KRAB-dCas9-P2A-mCherryKRAB-dCas9-P2A-mCherry fusion (Homo sapiens)Mammalian Expression, Lentiviral, CRISPRGenome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9. 2nd Generation Lentiviral vector. Expresses an N-terminal KRAB-dCas9 fusion protein and mCherry pHR Add to Cart
60955pU6-sgRNA EF1Alpha-puro-T2A-BFPsgGFP-NT2, puro-T2A-BFPMammalian Expression, Lentiviral, CRISPRGenome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9. Parental vector for the CRISPRi/a libraries. Expresses an sgRNA from the U6 promoter and a puromycin resistance cassette and BFP from the EF1Alpha promoter pSICO derivative Add to Cart
62358pJW1504RPS2 fragment (Saccharomyces cerevisiae)yeast targetingPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. RPS2 HA-TEV-AVI pop-in/pop-out plasmid pRS306 Add to Cart
62359pJW1505RPL16A (Saccharomyces cerevisiae)yeast taggingPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. RPL16a HA-TEV-AVI pop-in/pop-out plasmid pRS306 Add to Cart
62360pJW1506RPL16B (Saccharomyces cerevisiae)yeast targetingPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. RPL16b HA-TEV-AVI pop-in/pop-out plasmid pRS306 Add to Cart
62361pJW1507c-terminal mVenus-BirA taggingyeast c-terminal tagging vectorPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. pFA6a -mVenus-BirA::HIS5 pFA6a Add to Cart
62362pJW1508BirA-mVenus-Ssh1 (Saccharomyces cerevisiae)Yeast ExpressionPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. pFA6a BirA-mVenus-SSH1::HIS5 pFA6a Add to Cart
62363pJW1509BirA-heh2-Ssh1 (Saccharomyces cerevisiae)Yeast ExpressionPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. pFA6a BirA-heh2 linker-SSH1::HIS5 pFA6a Add to Cart
62364pJW1510BirA-mVenus-Ubc6 tail anchor (Saccharomyces cerevisiae)Yeast ExpressionPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. pFA6a pSEC63-BirA-mVenus-UBC6-TA::HIS5 pFA6a Add to Cart
62365pJW1511Puro-T2A-AVITEVHAmmuRPL10A (Mus musculus)Mammalian Expression, LentiviralPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. pEF1a-puro-T2A-ATHmmuRPL10A pMK1047 Add to Cart
62366pJW15123xFLAG-BirA-mCherry-Sec61beta tail anchor (Homo sapiens)Mammalian Expression, LentiviralPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. N-terminal 3X FLAG fused to wt BirA - mCherry - sec61ß pInducer11 Add to Cart
62367pJW1234BirAYeast ExpressionPrinciples of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):1257521. doi: 10.1126/science.1257521. Epub 2014 Nov 6. pRS305 pPGK1-BirA::LEU2 pRS305 birA b3973, ECK3965, JW3941, bioR, dhbB Add to Cart
62383pJW1513su9-tagBFP (Synthetic)Yeast ExpressionTargeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522. pRS316-pTDH3-Su9-TagBFP pRS316 Add to Cart
62384pJW1514tev 3x FLAG (Synthetic)yeast c-terminal tagging vectorTargeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522. pCR2.1 linker-tev-linker-3X-FLAG::KanMX pCRII blunt topo Add to Cart
62385pJW1515OSM1-EGFP fusion (Saccharomyces cerevisiae)Yeast ExpressionTargeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522. pFA6a Osm1-yoEGFP::LEU2 pFA6a Add to Cart
62386pJW1516OSM1-EGFP fusion (Saccharomyces cerevisiae)Yeast ExpressionTargeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522. pFA6a Osm1(M1A)-yoEGFP::LEU2 pFA6a Add to Cart
62387pJW1517OSM1-EGFP fusion (Saccharomyces cerevisiae)Yeast ExpressionTargeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522. pFA6a Osm1(M33A)-yoEGFP::LEU2 pFA6a Add to Cart
62388pJW1518mCherry-BirA (Other)yeast c-terminal tagging vectorTargeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science. 2014 Nov 7;346(6210):748-51. doi: 10.1126/science.1257522. pFA6a -mCherry-BirA::HIS5 pFA6a Add to Cart
83969hCRISPRi-v2, genome-wide, top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Version 2 of the human CRISPRi genome wide library pCRISPRia-v2 Add to Cart
83971hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets pCRISPRia-v2 Add to Cart
83972hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRi Pooled Library targeting cancer and apoptosis genes pCRISPRia-v2 Add to Cart
83973hCRISPRi-v2, Stress and Proteostasis (h3), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRi Pooled Library targeting stress and proteostasis genes pCRISPRia-v2 Add to Cart
83974hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes pCRISPRia-v2 Add to Cart
83975hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRi Pooled Library targeting gene expression pCRISPRia-v2 Add to Cart
83976hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRi Pooled Library targeting membrane proteins pCRISPRia-v2 Add to Cart
83977hCRISPRi-v2, Unassigned (h7), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRi Pooled Library targeting unassigned genes pCRISPRia-v2 Add to Cart
83978hCRISPRa-v2, genome-wide, top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Version 2 of the human CRISPRa genome wide library pCRISPRia-v2 Add to Cart
83980hCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRa Pooled Library tartgeting kinsases, phosphatases and Drug Targets pCRISPRia-v2 Add to Cart
83981hCRISPRa-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRa Pooled Library targeting cancer and apoptosis genes pCRISPRia-v2 Add to Cart
83982hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRa Pooled Library targeting stress and proteostasis genes pCRISPRia-v2 Add to Cart
83983hCRISPRa-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes pCRISPRia-v2 Add to Cart
83984hCRISPRa-v2, Gene Expression (h5), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRa Pooled Library targeting gene expression pCRISPRia-v2 Add to Cart
83985hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRa Pooled Library targeting membrane proteins pCRISPRia-v2 Add to Cart
83986hCRISPRa-v2, Unassigned (h7), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Human CRISPRa Pooled Library targeting unassigned genes pCRISPRia-v2 Add to Cart
83987mCRISPRi-v2, genome-wide, top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Version 2 of the mouse CRISPRi genome wide library pCRISPRia-v2 Add to Cart
83989mCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets pCRISPRia-v2 Add to Cart
83990mCRISPRi-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library targeting cancer and apoptosis genes pCRISPRia-v2 Add to Cart
83991mCRISPRi-v2, Stress and Proteostasis (m3), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library targeting stress and proteostasis genes pCRISPRia-v2 Add to Cart
83992mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes pCRISPRia-v2 Add to Cart
83993mCRISPRi-v2, Gene Expression (m5), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library targeting gene expression pCRISPRia-v2 Add to Cart
83994mCRISPRi-v2, Membrane Proteins (m6), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library targeting membrane proteins pCRISPRia-v2 Add to Cart
83995mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library targeting unassigned genes pCRISPRia-v2 Add to Cart
83996mCRISPRa-v2, genome-wide, top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Version 2 of the mouse CRISPRa genome wide library pCRISPRia-v2 Add to Cart
83998mCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets pCRISPRia-v2 Add to Cart
83999mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes pCRISPRia-v2 Add to Cart
84000mCRISPRa-v2, Stress and Proteostasis (m3), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRi Pooled Library targeting stress and proteostasis genes pCRISPRia-v2 Add to Cart
84001mCRISPRa-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes pCRISPRia-v2 Add to Cart
84002mCRISPRa-v2, Gene Expression (m5), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRa Pooled Library targeting gene expression pCRISPRia-v2 Add to Cart
84003mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRa Pooled Library targeting membrane proteins pCRISPRia-v2 Add to Cart
84004mCRISPRa-v2, Unassigned (m7), top 5 sgRNAs/geneCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. Mouse CRISPRa Pooled Library targeting unassigned genes pCRISPRia-v2 Add to Cart
84219pMK1200Mammalian Expression, Lentiviral, RNAiIntegrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2317-26. doi: 10.1073/pnas.1307002110. Epub 2013 Jun 5. Lentiviral expression of shRNAs, compatible with double-shRNA expression, EF1alpha promoter, mCherry pSicoR Add to Cart
84220pMK1221Mammalian Expression, Lentiviral, RNAiNext-generation libraries for robust RNA interference-based genome-wide screens. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3384-91. doi: 10.1073/pnas.1508821112. Epub 2015 Jun 15. Lentiviral expression of shRNAs, compatible with double-shRNA expression, SFFV promoter, mCherry pSicoR Add to Cart
84221pMK1224Mammalian Expression, Lentiviral, RNAiNext-generation libraries for robust RNA interference-based genome-wide screens. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3384-91. doi: 10.1073/pnas.1508821112. Epub 2015 Jun 15. Lentiviral expression of shRNAs, compatible with double-shRNA expression, SFFV promoter, BFP pSicoR Add to Cart
84832pCRISPRia-v2sgRNA, puro-T2A-BFPMammalian Expression, Lentiviral, CRISPRCompact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016 Sep 23;5. pii: e19760. doi: 10.7554/eLife.19760. CRISPRi/a V2 library parental plasmid pSICO derivative Add to Cart
85967pBA439sgGFP-NT2, puro-T2A-BFPMammalian Expression, Lentiviral, CRISPRA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. Perturb-seq vector backbone pSICO derivative Add to Cart
85968Perturb-seq GBC librarysgGFP-NT2, puro-T2A-BFPMammalian Expression, Lentiviral, CRISPRA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. Perturb-seq GBC library pBA439-based library Add to Cart
85969pMH0001dCas9 (Other)Mammalian Expression, LentiviralA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. UCOE-SFFV-dCas9-BFP-KRAB pHR-SFFV-dCas9-BFP-KRAB Add to Cart
85970pBA407mCherry (Other), NeoMammalian Expression, LentiviralA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. UPRE-mCh-Ubc-Neo pInducer20 derivative Add to Cart
85971pBA409sfGFP, NeoMammalian Expression, LentiviralA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. EF1a-sfGFP-Ubc-Neo pInducer20 derivative Add to Cart
85995pMJ114sgGFP-NT2, puro-T2A-BFPMammalian Expression, Lentiviral, CRISPRA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. One-guide Perturb-seq vector backbone; modified bovine U6 promoter; original constant region pSICO derivative Add to Cart
85996pMJ179EGFP-NT2_cr2, puro-T2A-BFPMammalian Expression, Lentiviral, CRISPRA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. One-guide Perturb-seq vector backbone; modified mouse U6 promoter; constant region 2 pSICO derivative Add to Cart
85997pMJ117EGFP-NT2_cr3, puro-T2A-BFPMammalian Expression, Lentiviral, CRISPRA Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. One-guide Perturb-seq vector backbone; modified human U6 promoter; constant region 3 pSICO derivative Add to Cart
86538CRISPRi non-coding library (CRiNCL) - Common to all 7 cell linesCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86539CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell linesCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86540CRISPRi non-coding library (CRiNCL) - Unique to iPSCCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86541CRISPRi non-coding library (CRiNCL) - Unique to HFFCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86542CRISPRi non-coding library (CRiNCL) - Unique to U87CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86543CRISPRi non-coding library (CRiNCL) - Unique to HEK293TCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86544CRISPRi non-coding library (CRiNCL) - Unique to K562CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86545CRISPRi non-coding library (CRiNCL) - Unique to HeLaCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86546CRISPRi non-coding library (CRiNCL) - Unique to MCF7CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86547CRISPRi non-coding library (CRiNCL) - U87 & HEK293TCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86548CRISPRi non-coding library (CRiNCL) - K562, HeLa, & MCF7CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86549CRISPRi non-coding library (CRiNCL) - K562 & HeLaCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart
86550CRISPRi non-coding library (CRiNCL) - iPSC & HFFCRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science. 2017 Jan 06. Vol. 355, Issue 6320. pii: aah7111. pCRISPRia-v2 Add to Cart