375 results

1. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

   Pooled Library

   #92386

   Purpose

   Crispri

   Depositor

   David Root, John Doench

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Use

   Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

2. Pooled sgRNA libraries Set 1 and Set 2 for Pseudomonas aeruginosa PA14

   Pooled Library

   #1000000254

   Depositor

   Xue Liu

   Available since

   June 5, 2025

   Availability

   Academic Institutions and Nonprofits only

3. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

   Pooled Library

   #1000000111

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   David Root, John Doench

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

4. Watermelon

   Pooled Library

   #155257

   Purpose

   Lineage tracing library

   Depositor

   Joan Brugge, Aviv Regev

   Article

   Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   Oct. 15, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Human Epigenetic Knockout Library

   Pooled Library

   #162256

   Purpose

   Lentiviral CRISPR library targets human epigenetic genes

   Depositor

   Kivanc Birsoy

   Article

   Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75316

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

7. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Robert Manguso, Gabriel Griffin, Bradley Bernstein

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

9. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050

   Pooled Library

   #1000000114

   Purpose

   Genome-wide CRISPR gRNA pooled library for inhibition of human genes

   Depositor

   David Root, John Doench

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

10. Human ubiquitination-related proteins CRISPR KO library

    Pooled Library

    #174592

    Purpose

    CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

    Depositor

    Juan Bonifacino

    Article

    Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Mouse sgRNA library Brie in lentiGuide-Puro

    Pooled Library

    #73633

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

12. mCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

    Pooled Library

    #83996

    Purpose

    Version 2 of the mouse CRISPRa genome wide library

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Use

    Lentiviral

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

13. STICR_IndexE

    Pooled Library

    #180483

    Purpose

    High Complexity Lentiviral Barcode Library

    Depositor

    Tomasz Nowakowski

    Article

    Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

14. Human Genome-Wide Reduced Double-gRNA library

    Pooled Library

    #137999

    Purpose

    This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.

    Depositor

    Leopold Parts

    Article

    Peets et al bioRxiv 859652

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

15. LARRYv2-EGFP library 1

    Pooled Library

    #233215

    Purpose

    Barcoding pooled library

    Depositor

    Alejo Rodriguez-Fraticelli

    Article

    Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    March 6, 2025

    Availability

    Academic Institutions and Nonprofits only

16. hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

    Pooled Library

    #83969

    Purpose

    Version 2 of the human CRISPRi genome wide library

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Use

    Lentiviral

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

17. Inzolia library in pRDA_550

    Pooled Library

    #209552

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

18. Inzolia library in pRDA_052

    Pooled Library

    #209551

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

19. Human CRISPR Metabolic Gene Knockout Library

    Pooled Library

    #110066

    Purpose

    Encodes gRNAs for targeting metabolic genes in CRISPR screens.

    Depositor

    David Sabatini

    Article

    Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

    Use

    Lentiviral

    Available since

    May 4, 2018

    Availability

    Academic Institutions and Nonprofits only

20. PB-EF1a-Puro-V8.2

    Pooled Library

    #178943

    Purpose

    Barcoding library for the macsGESTALT inducible lineage recording system

    Depositor

    Christopher Lengner

    Article

    Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

    Expression

    Mammalian

    Available since

    March 22, 2022

    Availability

    Academic Institutions and Nonprofits only