405 results

Showing: 21 - 40 of 405 results

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Membrane protein gRNA library

Pooled Library

#113345

Purpose

Activation library targeting the promoters of 6,213 genes that encode at least one putative membrane-associated protein isoform.

Depositor

Gavin Wright

Article

Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

Species

Homo sapiens

Use

Lentiviral

Available Since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Kinases

Pooled Library

#51044

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, genome-wide, 10 sgRNAs/gene

Pooled Library

#1000000091

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

Jonathan Weissman

Available Since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only
Lenti-human-TF-gRNA-puromycin

Pooled Library

#162275

Purpose

Knockout library targeting a set of human transcription factors for loss-of-function screening.

Depositor

Chunliang Li

Article

Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

Species

Homo sapiens

Use

Lentiviral

Available Since

Dec. 15, 2020

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins

Pooled Library

#101929

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available Since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Mouse genome-wide lentiviral CRISPR gRNA library version 2

Pooled Library

#67988

Purpose

Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Depositor

Kosuke Yusa

Article

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Species

Homo sapiens, Mus musculus, and Synthetic

Use

CRISPR and Lentiviral

Available Since

Oct. 14, 2016

Availability

Academic Institutions and Nonprofits only
Mouse metabolism knockout library

Pooled Library

#160129

Purpose

Targets mouse metabolic genes and includes most metabolic enzymes and transporters.

Depositor

Kivanc Birsoy

Article

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Nov. 10, 2020

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Nuclear

Pooled Library

#51047

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available Since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

Pooled Library

#1000000083

Purpose

CRISPR gRNA knockout pooled library for targeting the human kinome

Depositor

John Doench, David Root

Available Since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

Pooled Library

#83978

Purpose

Version 2 of the human CRISPRa genome wide library

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Use

Lentiviral

Available Since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only
Human genome-wide lentiviral CRISPR gRNA library version 1

Pooled Library

#67989

Purpose

Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Depositor

Kosuke Yusa

Article

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Species

Homo sapiens, Mus musculus, and Synthetic

Use

CRISPR and Lentiviral

Available Since

Oct. 14, 2016

Availability

Academic Institutions and Nonprofits only
ClonTracer Barcoding Library (2.5 ug)

Pooled Library

#67267

Purpose

High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

Depositor

Frank Stegmeier

Article

Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available Since

Sept. 11, 2015

Availability

Academic Institutions and Nonprofits only
pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

Pooled Library

#104861

Purpose

Retroviral library containing gRNAs from the Yusa lab Mouse improved genome-wide library v2.

Depositor

Sarah Teichmann

Article

Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

Available Since

Sept. 9, 2019

Availability

Academic Institutions and Nonprofits only
Bison sgRNA library

Pooled Library

#169942

Purpose

Knockout library targeting ubiquitin ligases, deubiquitinases, and control genes.

Depositor

Benjamin Ebert

Article

Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

Use

Lentiviral

Available Since

Sept. 9, 2021

Availability

Academic Institutions and Nonprofits only
Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

Pooled Library

#1000000113

Purpose

Genome-wide CRISPR gRNA pooled library for activation of mouse genes

Depositor

John Doench, David Root

Available Since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
RNA-binding protein pooled CRISPR knockout library

Pooled Library

#141438

Purpose

Knockout library targeting RNA-binding proteins with 10 guide RNAs per target.

Depositor

Eugene Yeo

Article

Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

May 28, 2020

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Pooled Library

#101927

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available Since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

Pooled Library

#83971

Purpose

Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

Pooled Library

#1000000082

Purpose

CRISPR gRNA knockout pooled library for targeting the human kinome

Depositor

John Doench, David Root

Available Since

June 27, 2016

Availability

Academic Institutions and Nonprofits only

Showing: 21 - 40 of 405 results

Results per page:

Sort results by:

More Filters

405 results

Membrane protein gRNA library

Human Lentiviral sgRNA Library - Kinases

hCRISPRa-v2, genome-wide, 10 sgRNAs/gene

Lenti-human-TF-gRNA-puromycin

Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins

Mouse genome-wide lentiviral CRISPR gRNA library version 2

Mouse metabolism knockout library

Human Lentiviral sgRNA Library - Nuclear

MORF library without GFP and mCherry controls

Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

hCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

Human genome-wide lentiviral CRISPR gRNA library version 1

ClonTracer Barcoding Library (2.5 ug)

pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

Bison sgRNA library

Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

RNA-binding protein pooled CRISPR knockout library

Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

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