380 results

1. Inzolia library in pRDA_052

   Pooled Library

   #209551

   Purpose

   The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

   Depositor

   John Doench

   Article

   Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

2. TCR Rapid Assembly for Functional Testing (TCRAFT)

   Pooled Library

   #1000000264

   Depositor

   Michael Birnbaum

   Available since

   Aug. 12, 2025

   Availability

   Academic Institutions and Nonprofits only

3. The Human Druggable CRISPR library

   Pooled Library

   #200013

   Purpose

   The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

   Depositor

   Lianxin Liu

   Article

   Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 9, 2023

   Availability

   Academic Institutions and Nonprofits only

4. MORF library without GFP and mCherry controls

   Pooled Library

   #192821

   Purpose

   Barcoded transcription factor ORF library for high throughput screening

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Jan. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

5. MORF Library Kit with GFP and mCherry controls

   Pooled Library

   #1000000218

   Depositor

   Feng Zhang

   Available since

   March 24, 2023

   Availability

   Academic Institutions and Nonprofits only

6. Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

   Pooled Library

   #1000000049

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Feng Zhang

   Available since

   May 8, 2014

   Availability

   Academic Institutions and Nonprofits only

7. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Robert Manguso, Bradley Bernstein, Gabriel Griffin

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

8. Lenti-human-TF-gRNA-puromycin

   Pooled Library

   #162275

   Purpose

   This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

   Depositor

   Chunliang Li

   Article

   Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Dec. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

9. hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

   Pooled Library

   #83969

   Purpose

   Version 2 of the human CRISPRi genome wide library

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Use

   Lentiviral

   Available since

   Nov. 15, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Mouse sgRNA library Brie in lentiGuide-Puro

    Pooled Library

    #73633

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

11. LARRYv2-EGFP library 1

    Pooled Library

    #233215

    Purpose

    Barcoding pooled library

    Depositor

    Alejo Rodriguez-Fraticelli

    Article

    Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    March 6, 2025

    Availability

    Academic Institutions and Nonprofits only

12. Mouse sphingolipid metabolism knockout library

    Pooled Library

    #206249

    Purpose

    The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

13. ACER

    Pooled Library

    #226117

    Purpose

    The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

    Depositor

    Rui Lu

    Article

    Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

14. Murine cell surface protein knockout (McspKO) library

    Pooled Library

    #200445

    Purpose

    A CRISPR library targeting 1,157 cell surface genes and 98 control genes with four sgRNAs per gene

    Depositor

    Junjie Chen

    Article

    Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR, Lentiviral, and Mouse Targeting

    Available since

    Oct. 26, 2023

    Availability

    Academic Institutions and Nonprofits only

15. Human Lipid Droplet and Metabolism Library

    Pooled Library

    #191535

    Purpose

    Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

    Depositor

    James Olzmann

    Article

    Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    March 1, 2023

    Availability

    Academic Institutions and Nonprofits only

16. PB-EF1a-Puro-V8.2

    Pooled Library

    #178943

    Purpose

    Barcoding library for the macsGESTALT inducible lineage recording system

    Depositor

    Christopher Lengner

    Article

    Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

    Expression

    Mammalian

    Available since

    March 22, 2022

    Availability

    Academic Institutions and Nonprofits only

17. hCRISPRi_dual_1_2

    Pooled Library

    #187246

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

18. Mouse sgRNA library Brie in lentiCRISPRv2

    Pooled Library

    #73632

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

19. Ma-PylRS-lib1

    Pooled Library

    #224585

    Purpose

    Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

    Depositor

    Ryan Mehl

    Article

    Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

    Expression

    Bacterial

    Species

    Methanomethylophilus alvus

    Available since

    Jan. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

20. Human SAM library in lenti sgRNA(MS2)_puro backbone

    Pooled Library

    #1000000074

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only