380 results

1. Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

   Pooled Library

   #159392

   Purpose

   Mouse lentiviral genome-wide CRISPR library

   Depositor

   Jason Moffat

   Article

   Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 9, 2020

   Availability

   Academic Institutions and Nonprofits only

2. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

   Pooled Library

   #227672

   Purpose

   RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

   Depositor

   Tomasz Nowakowski, Cathryn Cadwell

   Article

   Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

   Expression

   Mammalian

   Species

   Synthetic

   Available since

   Feb. 12, 2025

   Availability

   Academic Institutions and Nonprofits only

3. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

   Pooled Library

   #75317

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

4. Pooled sgRNA libraries Set 1 and Set 2 for Pseudomonas aeruginosa PA14

   Pooled Library

   #1000000254

   Depositor

   Xue Liu

   Available since

   June 5, 2025

   Availability

   Academic Institutions and Nonprofits only

5. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

6. RLC11

   Pooled Library

   #163955

   Purpose

   RLC11 pooled library

   Depositor

   Jeremy Rock

   Article

   Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

   Expression

   Bacterial

   Use

   CRISPR

   Available since

   Oct. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

7. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75316

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

8. LARRYv2-EGFP library 2

   Pooled Library

   #233216

   Purpose

   Barcoding pooled library

   Depositor

   Alejo Rodriguez-Fraticelli

   Article

   Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   March 6, 2025

   Availability

   Academic Institutions and Nonprofits only

9. Human ubiquitination-related proteins CRISPR KO library

   Pooled Library

   #174592

   Purpose

   CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

   Depositor

   Juan Bonifacino

   Article

   Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

10. Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

    Pooled Library

    #101931

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

11. pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

    Pooled Library

    #104861

    Depositor

    Sarah Teichmann

    Article

    Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

    Available since

    Sept. 9, 2019

    Availability

    Academic Institutions and Nonprofits only

12. Human Metabolic Gene CRISPRa sgRNA library

    Pooled Library

    #187080

    Purpose

    Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

    Depositor

    Kivanc Birsoy

    Article

    Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

13. Xiaole Shirley Liu lab Human CRISPR lentiviral library

    Pooled Library

    #1000000132

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Xiaole Shirley Liu

    Available since

    June 13, 2018

    Availability

    Academic Institutions and Nonprofits only

14. Barcode Library 0 (BCL0)

    Pooled Library

    #179851

    Purpose

    Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

    Depositor

    Jason Moffat

    Article

    Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

15. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

    Pooled Library

    #92379

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Has Service

    Lentiviral Prep

    Use

    Lentiviral

    Available since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

16. LARRYv2-T-Sapphire library 1

    Pooled Library

    #233213

    Purpose

    Barcoding pooled library

    Depositor

    Alejo Rodriguez-Fraticelli

    Article

    Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    March 6, 2025

    Availability

    Academic Institutions and Nonprofits only

17. Human Kinase Domain-Focused CRISPR Knockout Library

    Pooled Library

    #117725

    Purpose

    gRNAs targeting the kinase domain of human protein kinases

    Depositor

    Christopher Vakoc

    Article

    Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

18. SPLINTR mCHERRY v1

    Pooled Library

    #179775

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

19. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92380

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

20. Human sgRNA library Gattinara in pRDA_118 backbone

    Pooled Library

    #136986

    Purpose

    Expresses sgRNAs targeting human genes

    Depositor

    John Doench

    Article

    DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 24, 2020

    Availability

    Academic Institutions and Nonprofits only