390 results

1. Human Lentiviral sgRNA Library - Ribosomal Proteins

   Pooled Library

   #51045

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for ribosomal gene targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

2. Human SAM Library in lenti sgRNA(MS2)_zeo backbone

   Pooled Library

   #1000000057

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   Feng Zhang

   Available Since

   Jan. 16, 2015

   Availability

   Academic Institutions and Nonprofits only

3. Lourido Toxoplasma CRISPR Library V1

   Pooled Library

   #80636

   Purpose

   Knockout library targeting 8,158 predicted protein-coding gene in Toxoplasma gondii.

   Depositor

   Sebastian Lourido

   Article

   Sidik et al Cell. 2016 Sep 8;166(6):1423-1435.e12. d

   Available Since

   Sept. 19, 2016

   Availability

   Academic Institutions and Nonprofits only

4. SPECS library

   Pooled Library

   #127842

   Purpose

   For performing high-throughput cell state-specific synthetic promoter screening

   Depositor

   Timothy Lu

   Article

   Wu et al Nat Commun. 2019 Jun 28;10(1):2880. doi:

   Species

   Synthetic

   Use

   Lentiviral

   Available Since

   Aug. 22, 2020

   Availability

   Academic Institutions and Nonprofits only

5. hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/gene

   Pooled Library

   #83975

   Purpose

   Human CRISPRi Pooled Library targeting gene expression

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

6. pre-associated oBC-mBC backbone (p025)

   Pooled Library

   #194097

   Purpose

   pre-associated oBC-mBC backbone (p025), can insert additional reporter constructs

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

7. pre-associated oBC-minP-GFP-mBC backbone (p043)

   Pooled Library

   #194098

   Purpose

   pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

8. Watermelon

   Pooled Library

   #155257

   Purpose

   Lineage tracing library

   Depositor

   Joan Brugge, Aviv Regev

   Article

   Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   Oct. 15, 2021

   Availability

   Academic Institutions and Nonprofits only

9. hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

   Pooled Library

   #83972

   Purpose

   Human CRISPRi Pooled Library targeting cancer and apoptosis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Mouse GeCKO Lentiviral sgRNA Library (LentiGuide-Puro)

    Pooled Library

    #1000000053

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Feng Zhang

    Available Since

    July 23, 2014

    Availability

    Academic Institutions and Nonprofits only

11. hCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

    Pooled Library

    #83978

    Purpose

    Version 2 of the human CRISPRa genome wide library

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Use

    Lentiviral

    Available Since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

12. RNA-binding protein pooled CRISPR knockout library

    Pooled Library

    #141438

    Purpose

    Knockout library targeting RNA-binding proteins with 10 guide RNAs per target.

    Depositor

    Eugene Yeo

    Article

    Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    May 28, 2020

    Availability

    Academic Institutions and Nonprofits only

13. pSMAL-CellTag-V2

    Pooled Library

    #115644

    Purpose

    Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Has Service

    Concentrated Lentiviral Prep

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Dec. 5, 2018

    Availability

    Academic Institutions and Nonprofits only

14. Jacquere (all-in-one vector)

    Pooled Library

    #247027

    Purpose

    Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

    Depositor

    John Doench, David Root

    Article

    Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

15. Mouse Metabolism Library

    Pooled Library

    #163966

    Purpose

    Knockout library targeting mouse metabolic genes.

    Depositor

    Alec Kimmelman

    Article

    Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

    Use

    CRISPR and Lentiviral

    Available Since

    July 1, 2021

    Availability

    Academic Institutions and Nonprofits only

16. Mouse SAM Library in lenti sgRNA(MS2)_puro optimized backbone

    Pooled Library

    #1000000075

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Feng Zhang

    Available Since

    March 17, 2016

    Availability

    Academic Institutions and Nonprofits only

17. Human ubiquitination-related proteins CRISPR KO library

    Pooled Library

    #174592

    Purpose

    Targets human ubiquitation-related proteins and deubiquitinating enzymes.

    Depositor

    Juan Bonifacino

    Article

    Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

18. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

    Pooled Library

    #1000000113

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    John Doench, David Root

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

19. LV2btCRISPRko.v1

    Pooled Library

    #213927

    Purpose

    Uses lentivirus to deliver the library into hard-to-transduce cells

    Depositor

    Wenfang Spring Tan

    Article

    Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only

20. PBbtCRISPRko.v1

    Pooled Library

    #213928

    Purpose

    Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

    Depositor

    Wenfang Spring Tan

    Article

    Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only