390 results

1. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Gene Expression

   Pooled Library

   #1000000123

   Purpose

   CRISPR gRNA mouse knockout pooled library - Gene expression

   Depositor

   Michael Bassik

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

2. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000096

   Purpose

   CRISPR gRNA knockout pooled library for targeting the mouse genome

   Depositor

   Eric Lander, David Sabatini

   Available Since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

3. Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3

   Pooled Library

   #101934

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

4. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Eric Lander, David Sabatini

   Available Since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

5. scQers promoter control #2 (low: no promoter, p029)

   Pooled Library

   #217421

   Purpose

   scQers promoter control #2 (low: no promoter, p029)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

6. scQers promoter control #3 (intermediate: UBC promoter, p041)

   Pooled Library

   #217422

   Purpose

   scQers promoter control #3 (intermediate: UBC promoter, p041)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

7. scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

   Pooled Library

   #217423

   Purpose

   scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

8. pre-associated oBC-mBC backbone (p025)

   Pooled Library

   #194097

   Purpose

   pre-associated oBC-mBC backbone (p025), can insert additional reporter constructs

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

9. TRE-MPRA_minTK Library

   Pooled Library

   #201014

   Purpose

   Massively parallel reporter assay (MPRA) library with minTK promoter

   Depositor

   Justin English

   Article

   Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

   Expression

   Mammalian

   Use

   Luciferase

   Available Since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

10. hCRISPRa_dual_1_2

    Pooled Library

    #187249

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

11. Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis

    Pooled Library

    #101930

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available Since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

12. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

    Pooled Library

    #1000000122

    Purpose

    CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

    Depositor

    Michael Bassik

    Available Since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

13. RLC11

    Pooled Library

    #163955

    Purpose

    RLC11 pooled library

    Depositor

    Jeremy Rock

    Article

    Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

    Expression

    Bacterial

    Use

    CRISPR

    Available Since

    Oct. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

14. Xiaole Shirley Liu lab Human CRISPR lentiviral library

    Pooled Library

    #1000000132

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Xiaole Shirley Liu

    Available Since

    June 13, 2018

    Availability

    Academic Institutions and Nonprofits only

15. pLCKO2::TKOv3

    Pooled Library

    #125517

    Purpose

    Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

    Depositor

    Jason Moffat

    Article

    Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 1, 2019

    Availability

    Academic Institutions and Nonprofits only

16. ClonTracer Barcoding Library (2.5 ug)

    Pooled Library

    #67267

    Purpose

    High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

    Depositor

    Frank Stegmeier

    Article

    Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 11, 2015

    Availability

    Academic Institutions and Nonprofits only

17. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75314

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

18. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92380

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

19. Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

    Pooled Library

    #161769

    Purpose

    Inducible CRISPRi library

    Depositor

    Nicholas Ingolia

    Article

    McGlincy et al BMC Genomics. 2021 Mar 23;22(1):205. doi

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available Since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

20. Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

    Pooled Library

    #171531

    Purpose

    Pooled gRNA library against human ubiquitination and de-ubiquitination complex genes (UBDUB)

    Depositor

    Chunliang Li

    Article

    Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    June 22, 2021

    Availability

    Academic Institutions and Nonprofits only