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408 results

Showing: 181 - 200 of 408 results

  1. Mouse Validation (mVAL) CRISPR Library

    Pooled library
    #159391
    Purpose
    Targets 182 immune evasion genes. Designed for loss-of-function screening against genes shown to increase sensistivity or resistance of cancer cells to cytotoxic T lymphocyte-mediated toxicity.
    Depositor
    Jason Moffat
    Publication
    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:
    Expression
    Mammalian
    Species
    Mus musculus
    Use
    CRISPR and Lentiviral
    Available since
    Nov. 9, 2020
    Availability
    Academic Institutions and Nonprofits only

  7. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

    Pooled library
    #75315
    Purpose
    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls
    Depositor
    John Doench, David Root
    Publication
    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103
    Expression
    Mammalian
    Use
    CRISPR and Lentiviral
    Available since
    June 27, 2016
    Availability
    Academic Institutions and Nonprofits only
    Cited by
    3 Articles

  11. BARBEKO sgRNA library

    Pooled library
    #174163
    Purpose
    Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.
    Depositor
    Wensheng Wei
    Publication
    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 31, 2021
    Availability
    Academic Institutions and Nonprofits only
Showing: 181 - 200 of 408 results