374 results

1. mCRISPRa-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

   Pooled Library

   #83999

   Purpose

   Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

2. Drosophila_sgRNA_group_3

   Pooled Library

   #134584

   Purpose

   Targets all other Drosophila genes not included in Groups 1 and 2

   Depositor

   Norbert Perrimon

   Article

   Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

   Expression

   Insect

   Species

   Drosophila melanogaster

   Use

   CRISPR

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

3. Drosophila_sgRNA_group_1

   Pooled Library

   #134582

   Purpose

   Targets kinases, phosphatases, and Drosophila orthologs of drug targets

   Depositor

   Norbert Perrimon

   Article

   Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

   Expression

   Insect

   Species

   Drosophila melanogaster

   Use

   CRISPR

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Liu Lab MusCK (A + B)

   Pooled Library

   #1000000178

   Depositor

   Xiaole Shirley Liu

   Available since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92383

   Purpose

   CRISPRa

   Depositor

   David Root, John Doench

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

6. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92379

   Purpose

   CRISPRa

   Depositor

   David Root, John Doench

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Has Service

   Lentiviral Prep

   Use

   Lentiviral

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

7. hCRISPRa-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

   Pooled Library

   #83983

   Purpose

   Human CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Human Lentiviral sgRNA Library - Kinases

   Pooled Library

   #51044

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

   Depositor

   David Sabatini, Eric Lander

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

9. Synuclein VHH Immune Library

   Pooled Library

   #1000000071

   Purpose

   Synuclein phagemid VHH phage display library

   Depositor

   Michael J Fox Foundation MJFF, Anne Messer

   Available since

   June 14, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

10. Mouse Base Editing Sensor Library

    Pooled Library

    #179217

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

11. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

    Pooled Library

    #1000000096

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    David Sabatini, Eric Lander

    Available since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

12. mCRISPRa-v2, Gene Expression (m5), top 5 sgRNAs/gene

    Pooled Library

    #84002

    Purpose

    Mouse CRISPRa Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

13. Human Lentiviral sgRNA Library - Nuclear

    Pooled Library

    #51047

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

14. ClonTracer Barcoding Library (7.5 ug)

    Pooled Library

    #69830

    Purpose

    High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

    Depositor

    Frank Stegmeier

    Article

    Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 11, 2015

    Availability

    Academic Institutions and Nonprofits only

15. hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

    Pooled Library

    #83982

    Purpose

    Human CRISPRa Pooled Library targeting stress and proteostasis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

16. mCRISPRa-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000093

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Jonathan Weissman

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

17. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

    Pooled Library

    #75312

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

18. Barcode Library 1 (BCL1)

    Pooled Library

    #179852

    Purpose

    Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

    Depositor

    Jason Moffat

    Article

    Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

19. Human CRISPR Knockout Pooled Library (H3)

    Pooled Library

    #133914

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome - version H3

    Depositor

    Xiaole Shirley Liu, Myles Brown

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Jan. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

20. pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

    Pooled Library

    #199601

    Purpose

    pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

    Depositor

    George Church

    Article

    Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

    Expression

    Mammalian

    Species

    Aav2

    Use

    AAV

    Available since

    June 13, 2023

    Availability

    Academic Institutions and Nonprofits only