374 results

1. hCRISPRa-v2, Unassigned (h7), top 5 sgRNAs/gene

   Pooled Library

   #83986

   Purpose

   Human CRISPRa Pooled Library targeting unassigned genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

2. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

   Pooled Library

   #89640

   Purpose

   Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

   Depositor

   Wensheng Wei

   Article

   Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 17, 2017

   Availability

   Academic Institutions and Nonprofits only

3. mCRISPRa-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

   Pooled Library

   #84001

   Purpose

   Mouse CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

4. mCRISPRa-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

   Pooled Library

   #84000

   Purpose

   Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

5. mCRISPRa-v2, Unassigned (m7), top 5 sgRNAs/gene

   Pooled Library

   #84004

   Purpose

   Mouse CRISPRa Pooled Library targeting unassigned genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

6. STICR_Index3

   Pooled Library

   #186335

   Purpose

   High Complexity Lentiviral Barcode Library

   Depositor

   Tomasz Nowakowski

   Article

   Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 12, 2022

   Availability

   Academic Institutions and Nonprofits only

7. Human lentiviral CRISPR library_v1

   Pooled Library

   #69763

   Purpose

   Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

   Depositor

   Haoquan Wu

   Article

   Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

8. CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

   Pooled Library

   #86543

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

9. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   David Sabatini, Eric Lander

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

10. CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

    Pooled Library

    #86538

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

11. Human Lentiviral sgRNA Library - Cell Cycle

    Pooled Library

    #51046

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

12. hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

    Pooled Library

    #83972

    Purpose

    Human CRISPRi Pooled Library targeting cancer and apoptosis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

13. Human Lentiviral sgRNA Library - Control

    Pooled Library

    #51048

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

14. SARS-CoV-2 RBD Wuhan-Hu-1 SSM Library

    Pooled Library

    #1000000182

    Depositor

    Jesse Bloom

    Available since

    June 14, 2022

    Availability

    Academic Institutions and Nonprofits only

15. pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

    Pooled Library

    #198050

    Purpose

    By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

    Depositor

    George Church

    Article

    Jain et al bioRxiv 2023.01.31.526541

    Expression

    Mammalian

    Use

    AAV

    Available since

    May 4, 2023

    Availability

    Academic Institutions and Nonprofits only

16. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

    Pooled Library

    #227672

    Purpose

    RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

    Depositor

    Tomasz Nowakowski, Cathryn Cadwell

    Article

    Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

    Expression

    Mammalian

    Species

    Synthetic

    Available since

    Feb. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

17. PYR1 Double Mutant Library

    Pooled Library

    #1000000181

    Depositor

    Timothy Whitehead

    Available since

    June 21, 2022

    Availability

    Academic Institutions and Nonprofits only

18. sgRNA pool for Streptococcus pneumoniae

    Pooled Library

    #170432

    Purpose

    CRISPR library targeting S. pneumoniae D39V

    Depositor

    Jan-Willem Veening

    Article

    Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

    Expression

    Bacterial

    Use

    CRISPR

    Available since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

19. pEPIP_PepTile_40merFragments_65CancerDrivers

    Pooled Library

    #172109

    Purpose

    Lentiviral peptide expression library for overexpression fitness screening

    Depositor

    Prashant Mali

    Article

    Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

    Use

    Lentiviral

    Available since

    Oct. 21, 2021

    Availability

    Academic Institutions and Nonprofits only

20. hCRISPRi-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

    Pooled Library

    #83973

    Purpose

    Human CRISPRi Pooled Library targeting stress and proteostasis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only