379 results

1. SARS-CoV-2 RBD BA.2.86 SSM Library

   Pooled Library

   #1000000248

   Depositor

   Tyler Starr

   Available since

   Sept. 6, 2024

   Availability

   Academic Institutions and Nonprofits only

2. CRISPRi non-coding library (CRiNCL) - Unique to iPSC

   Pooled Library

   #86540

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

3. Sabatini/Lander Lab Ras synthetic lethal candidate focused human sgRNA library in lentiCRISPRv1

   Pooled Library

   #92352

   Purpose

   contains 6,661 sgRNAs (comprising 499 intergenic control sgRNAs and 6,162 sgRNAs targeting 132 control and candidate Ras synthetic lethal genes at up to 50 sgRNAs per gene)

   Depositor

   David Sabatini, Eric Lander

   Article

   Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

   Species

   Homo sapiens

   Available since

   June 7, 2017

   Availability

   Academic Institutions and Nonprofits only

4. CHyMErA Large-Scale Exon Deletion hgRNA Library

   Pooled Library

   #209736

   Purpose

   CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

5. EFS-mTSG

   Pooled Library

   #113584

   Purpose

   AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

   Depositor

   Sidi Chen

   Article

   Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

   Expression

   Mammalian

   Use

   AAV, CRISPR, Lentiviral, and Luciferase

   Available since

   July 23, 2019

   Availability

   Academic Institutions and Nonprofits only

6. CRISPRi non-coding library (CRiNCL) - Unique to U87

   Pooled Library

   #86542

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

7. CRISPRi non-coding library (CRiNCL) - Unique to MCF7

   Pooled Library

   #86546

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

8. SARS-CoV-2 RBD Omicron BA.2 SSM Library

   Pooled Library

   #1000000188

   Depositor

   Jesse Bloom

   Available since

   June 14, 2022

   Availability

   Academic Institutions and Nonprofits only

9. mTORC1 Focused library

   Pooled Library

   #164084

   Purpose

   Lentiviral CRISPR library targets human mTORC1 signaling pathway

   Depositor

   David Sabatini

   Article

   Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

10. CRISPRi non-coding library (CRiNCL) - U87 & HEK293T

    Pooled Library

    #86547

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

11. hCRISPRi-v2, Unassigned (h7), top 5 sgRNAs/gene

    Pooled Library

    #83977

    Purpose

    Human CRISPRi Pooled Library targeting unassigned genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

12. CRISPRi non-coding library (CRiNCL) - K562 & HeLa

    Pooled Library

    #86549

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

13. MYC-CRISPR

    Pooled Library

    #173195

    Purpose

    This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

    Depositor

    Agnieszka Dzikiewicz-Krawczyk

    Article

    Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 11, 2021

    Availability

    Academic Institutions and Nonprofits only

14. plIG-123_HA-GD2-28z_CAR_TF_Library

    Pooled Library

    #207478

    Purpose

    HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

15. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

    Pooled Library

    #207480

    Purpose

    HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

16. CRISPRi non-coding library (CRiNCL) - K562, HeLa, & MCF7

    Pooled Library

    #86548

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

17. CRISPRi non-coding library (CRiNCL) - Unique to HeLa

    Pooled Library

    #86545

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

18. iSPI_pSer_Subpool#2

    Pooled Library

    #188527

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

19. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

    Pooled Library

    #75313

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

20. iSPI_pSer_Full_library Kit

    Pooled Library

    #1000000209

    Depositor

    Jesse Rinehart

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only