398 results

#179217

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Lukas Dow

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

June 16, 2022

Academic Institutions and Nonprofits only

#86543

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#1000000181

Timothy Whitehead

June 21, 2022

Academic Institutions and Nonprofits only

#160135

Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#75315

Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

June 27, 2016

Academic Institutions and Nonprofits only

#140633

Enables genome-wide CRISPR screening at high MOI through use of barcoded gRNA plasmids.

Wensheng Wei

Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

April 21, 2020

Academic Institutions and Nonprofits only

#86544

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#86550

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#86539

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#198050

By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

George Church

Jain et al Elife. 2024 Mar 27;12:RP87730. doi: 10.7

May 4, 2023

Academic Institutions and Nonprofits only

#171172

Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs.

Alice Berger

Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

Sept. 28, 2021

Academic Institutions and Nonprofits only

#113585

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#1000000187

Jesse Bloom

June 14, 2022

Academic Institutions and Nonprofits only

#86541

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#138015

AAV library targeting transcriptional regulators expressed in cardiomyocytes.

William Pu

VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

April 17, 2020

Academic Institutions and Nonprofits only

#160133

Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#86540

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#153101

CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae

Irina Borodina

Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

Jan. 20, 2021

Academic Institutions and Nonprofits only

#138084

Targets 3' splice sites with paired gRNAs. Induces skipping of poison cassette exons and matching upstream constitutive exons. Compare loss of a constitutive coding exon with loss of a poison exon.

Robert Bradley

Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

March 6, 2020

Academic Institutions and Nonprofits only

#1000000232

Tyler Starr

Oct. 25, 2023

Academic Institutions and Nonprofits only