416 results

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SARS-CoV-2 RBD BA.2.86 SSM Library

Pooled library

#1000000248

Depositor

Tyler Starr

Available since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only
CHyMErA Large-Scale Exon Deletion hgRNA Library

Pooled library

#209736

Purpose

CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

Depositor

Thomas Gonatopoulos-Pournatzis

Publication

Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

June 20, 2024

Availability

Academic Institutions and Nonprofits only
PBbtCRISPRko.v1

Pooled library

#213928

Purpose

Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

Depositor

Wenfang Spring Tan

Publication

Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

April 9, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #2 (low: no promoter, p029)

Pooled library

#217421

Purpose

scQers promoter control #2 (low: no promoter, p029)

Depositor

Jay Shendure

Publication

Lalanne et al Nat Methods. 2024 Jun;21(6):983-993. doi

Expression

Bacterial and Mammalian

Use

RNAi

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #3 (intermediate: UBC promoter, p041)

Pooled library

#217422

Purpose

scQers promoter control #3 (intermediate: UBC promoter, p041)

Depositor

Jay Shendure

Publication

Lalanne et al Nat Methods. 2024 Jun;21(6):983-993. doi

Expression

Bacterial and Mammalian

Use

RNAi

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

Pooled library

#217423

Purpose

scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

Depositor

Jay Shendure

Publication

Lalanne et al Nat Methods. 2024 Jun;21(6):983-993. doi

Expression

Bacterial and Mammalian

Use

RNAi

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
lentiGuide-Puro-pKO-library

Pooled library

#190744

Purpose

Targets proximal poly(A) signal sequences in genes identified to be differentially polyadenylated in the mouse B16-F10 melanoma system.

Depositor

Robert Bradley

Publication

Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

Expression

Mammalian

Species

Mus musculus

Use

CRISPR, Lentiviral, and Mouse Targeting

Available since

Feb. 2, 2024

Availability

Academic Institutions and Nonprofits only
plIG-109_CD19-BBz_CAR_SR_Library

Pooled library

#207476

Purpose

CD19-BBz CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

Depositor

Alexander Marson

Publication

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
plIG-123_HA-GD2-28z_CAR_TF_Library

Pooled library

#207478

Purpose

HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

Depositor

Alexander Marson

Publication

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Species

Homo sapiens

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
plIG-128_HA-GD2-28z_CAR_TFxTF_Library

Pooled library

#207480

Purpose

HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

Depositor

Alexander Marson

Publication

Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

Use

CRISPR

Available since

Jan. 26, 2024

Availability

Academic Institutions and Nonprofits only
TRE-MPRA_minTK Library

Pooled library

#201014

Purpose

Massively parallel reporter assay (MPRA) library with minTK promoter

Depositor

Justin English

Publication

Zahm et al Nat Commun. 2024 Nov 28;15(1):10353. doi

Expression

Mammalian

Use

Luciferase

Available since

Oct. 31, 2023

Availability

Academic Institutions and Nonprofits only
mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

Pooled library

#197349

Purpose

To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

Depositor

Rebecca Voorhees, Jonathan Weissman

Publication

Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

Species

Homo sapiens

Use

Lentiviral

Available since

May 25, 2023

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
APA Variant and Reference Libraries

Pooled library

#1000000214

Depositor

Georg Seelig

Available since

March 31, 2023

Availability

Academic Institutions and Nonprofits only
iSPI_pSer_Subpool#2

Pooled library

#188527

Purpose

Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

Depositor

Jesse Rinehart

Publication

Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

Expression

Bacterial

Species

Homo sapiens

Available since

Dec. 14, 2022

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_3_4

Pooled library

#187250

Purpose

Ultra-compact, human genome-wide CRISPRa library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Marco Jost, Jonathan Weissman

Publication

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
hCRISPRa_dual_5_6

Pooled library

#187251

Purpose

Ultra-compact, human genome-wide CRISPRa library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Marco Jost, Jonathan Weissman

Publication

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 RBD Delta SSM Library

Pooled library

#1000000185

Depositor

Jesse Bloom

Available since

June 14, 2022

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library B

Pooled library

#174197

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Publication

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

Pooled library

#168776

Purpose

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Depositor

Timothy Whitehead

Publication

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

Pooled library

#168777

Purpose

Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

Depositor

Timothy Whitehead

Publication

Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

Expression

Yeast

Species

Sars-cov-2

Available since

Sept. 13, 2021

Availability

Academic Institutions and Nonprofits only

Showing: 301 - 320 of 416 results

Results per page:

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More Filters

416 results

SARS-CoV-2 RBD BA.2.86 SSM Library

CHyMErA Large-Scale Exon Deletion hgRNA Library

PBbtCRISPRko.v1

scQers promoter control #2 (low: no promoter, p029)

scQers promoter control #3 (intermediate: UBC promoter, p041)

scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

lentiGuide-Puro-pKO-library

plIG-109_CD19-BBz_CAR_SR_Library

plIG-123_HA-GD2-28z_CAR_TF_Library

plIG-128_HA-GD2-28z_CAR_TFxTF_Library

TRE-MPRA_minTK Library

mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

APA Variant and Reference Libraries

iSPI_pSer_Subpool#2

hCRISPRa_dual_3_4

hCRISPRa_dual_5_6

SARS-CoV-2 RBD Delta SSM Library

Liu Lab MusCK Library B

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

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