382 results

1. APA Variant and Reference Libraries

   Pooled Library

   #1000000214

   Depositor

   Georg Seelig

   Available Since

   March 31, 2023

   Availability

   Academic Institutions and Nonprofits only

2. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

   Pooled Library

   #168776

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

3. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

   Pooled Library

   #168777

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

4. SARS-CoV-2 Spike (S) Ectodomain Library C

   Pooled Library

   #157973

   Purpose

   Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Bacterial and Yeast

   Species

   Sars-cov-2

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

5. SARS-CoV-2 Spike (S) Ectodomain Library B

   Pooled Library

   #157972

   Purpose

   Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Bacterial and Yeast

   Species

   Sars-cov-2

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

6. SARS-CoV-2 Spike (S) Ectodomain Library A

   Pooled Library

   #157971

   Purpose

   Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Bacterial and Yeast

   Species

   Sars-cov-2

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

7. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

   Pooled Library

   #174296

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

8. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

   Pooled Library

   #174295

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

9. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

   Pooled Library

   #174294

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

10. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

    Pooled Library

    #174293

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136478

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

12. Jacquere (all-in-one vector)

    Pooled Library

    #247027

    Purpose

    Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

    Depositor

    John Doench, David Root

    Article

    Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

13. lenti_Puro_10N barcode

    Pooled Library

    #238546

    Purpose

    Lentiviral expression of a puromycin resistance cassette liked to a random 10N barcode

    Depositor

    Jonathan Weissman

    Article

    Koblan et al Science. 2025 Jul 24:eadx3800. doi: 10.1

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    Aug. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

14. lenti_Blast_10N barcode

    Pooled Library

    #238547

    Purpose

    Lentiviral expression of a Blasticidin resistance cassette liked to a random 10N barcode

    Depositor

    Jonathan Weissman

    Article

    Koblan et al Science. 2025 Jul 24:eadx3800. doi: 10.1

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    Aug. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

15. UMI-sgRNA-TF

    Pooled Library

    #234819

    Purpose

    Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice.

    Depositor

    Benjamin Ebert

    Article

    Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    June 11, 2025

    Availability

    Academic Institutions and Nonprofits only

16. UMI-sgRNA-CH

    Pooled Library

    #234820

    Purpose

    Unique molecular identifiers-linked sgRNA library targeting chromatin factors (CH) in mice.

    Depositor

    Benjamin Ebert

    Article

    Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    June 11, 2025

    Availability

    Academic Institutions and Nonprofits only

17. Pooled sgRNA Libraries Set 1 for Pseudomonas aeruginosa PA14

    Pooled Library

    #234855

    Purpose

    A CRISPRi library for inducible, genome-wide gene repression in Pseudomonas aeruginosa PA14.

    Depositor

    Xue Liu

    Article

    Zhang et al Nat Commun. 2025 Jul 1;16(1):5870. doi:

    Expression

    Bacterial

    Available Since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

18. CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

    Pooled Library

    #223064

    Purpose

    Optical pooled genome-scale CRISPR KO screening using Nuclear In-Situ Sequencing (NIS-Seq)

    Depositor

    Jonathan Schmid-Burgk

    Article

    Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    May 23, 2025

    Availability

    Academic Institutions and Nonprofits only

19. HR700_TP53Exon5mut

    Pooled Library

    #229137

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available Since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

20. HR700_TP53Exon6mut

    Pooled Library

    #229138

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available Since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits