388 results

1. lentiGuide-Puro-pKO-library

   Pooled Library

   #190744

   Purpose

   Targets proximal poly(A) signal sequences in genes identified to be differentially polyadenylated in the mouse B16-F10 melanoma system.

   Depositor

   Robert Bradley

   Article

   Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR, Lentiviral, and Mouse Targeting

   Available Since

   Feb. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

2. Liu Lab MusCK Library B

   Pooled Library

   #174197

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

3. EFS-mTSG

   Pooled Library

   #113584

   Purpose

   AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

   Depositor

   Sidi Chen

   Article

   Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

   Expression

   Mammalian

   Use

   AAV, CRISPR, Lentiviral, and Luciferase

   Available Since

   July 23, 2019

   Availability

   Academic Institutions and Nonprofits only

4. CRISPRi non-coding library (CRiNCL) - Unique to MCF7

   Pooled Library

   #86546

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available Since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

5. SARS-CoV-2 RBD BA.2.86 SSM Library

   Pooled Library

   #1000000248

   Depositor

   Tyler Starr

   Available Since

   Sept. 6, 2024

   Availability

   Academic Institutions and Nonprofits only

6. SARS-CoV-2 RBD Omicron BA.2 SSM Library

   Pooled Library

   #1000000188

   Depositor

   Jesse Bloom

   Available Since

   June 14, 2022

   Availability

   Academic Institutions and Nonprofits only

7. CRISPRi non-coding library (CRiNCL) - U87 & HEK293T

   Pooled Library

   #86547

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available Since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

8. CHyMErA Large-Scale Exon Deletion hgRNA Library

   Pooled Library

   #209736

   Purpose

   CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

9. hCRISPRi-v2, Unassigned (h7), top 5 sgRNAs/gene

   Pooled Library

   #83977

   Purpose

   Human CRISPRi Pooled Library targeting unassigned genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

10. CRISPRi non-coding library (CRiNCL) - K562 & HeLa

    Pooled Library

    #86549

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

11. CRISPRi non-coding library (CRiNCL) - K562, HeLa, & MCF7

    Pooled Library

    #86548

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

12. CRISPRi non-coding library (CRiNCL) - Unique to HeLa

    Pooled Library

    #86545

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

13. MYC-CRISPR

    Pooled Library

    #173195

    Purpose

    Knockout library targeting human E-boxes genome-wide.

    Depositor

    Agnieszka Dzikiewicz-Krawczyk

    Article

    Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 11, 2021

    Availability

    Academic Institutions and Nonprofits only

14. plIG-123_HA-GD2-28z_CAR_TF_Library

    Pooled Library

    #207478

    Purpose

    HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available Since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

15. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

    Pooled Library

    #207480

    Purpose

    HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Use

    CRISPR

    Available Since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

16. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

    Pooled Library

    #75313

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

17. Oxford Drosophila melanogaster Genome-wide CRISPR Library

    Pooled Library

    #64750

    Purpose

    Library designed for genomic targeting and screening in Drosophila cells. All possible gRNA target sites within the shared exonic regions on either DNA strand of the Drosophila genome were computed.

    Depositor

    Ji-Long Liu

    Article

    Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

    Expression

    Insect

    Species

    Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

    Use

    CRISPR

    Available Since

    March 7, 2016

    Availability

    Academic Institutions and Nonprofits only

18. S. rosetta Col- cDNA amplified library

    Pooled Library

    #62843

    Purpose

    amplified library of Salpingoeca rosetta

    Depositor

    Nicole King

    Article

    Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

    Expression

    Bacterial

    Species

    Salpingoeca rosetta

    Available Since

    June 16, 2015

    Availability

    Academic Institutions and Nonprofits only

19. iSPI_pSer_Subpool#2

    Pooled Library

    #188527

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available Since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

20. iSPI_pSer_Full_library Kit

    Pooled Library

    #1000000209

    Depositor

    Jesse Rinehart

    Available Since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only