374 results

1. hCRISPRa_dual_5_6

   Pooled Library

   #187251

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Jonathan Weissman, Marco Jost

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

2. SARS-CoV-2 RBD Delta SSM Library

   Pooled Library

   #1000000185

   Depositor

   Jesse Bloom

   Available since

   June 14, 2022

   Availability

   Academic Institutions and Nonprofits only

3. APA Variant and Reference Libraries

   Pooled Library

   #1000000214

   Depositor

   Georg Seelig

   Available since

   March 31, 2023

   Availability

   Academic Institutions and Nonprofits only

4. S. rosetta Col+ cDNA amplified library

   Pooled Library

   #62844

   Purpose

   amplified library of Salpingoeca rosetta from a colony rich culture which included the colony inducing bacteria Algoriphagus machipongonensis

   Depositor

   Nicole King

   Article

   Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

   Expression

   Bacterial

   Species

   Salpingoeca rosetta

   Available since

   June 16, 2015

   Availability

   Academic Institutions and Nonprofits only

5. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

   Pooled Library

   #168776

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

6. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

   Pooled Library

   #168777

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

7. SARS-CoV-2 Spike (S) Ectodomain Library C

   Pooled Library

   #157973

   Purpose

   Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Bacterial and Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

8. SARS-CoV-2 Spike (S) Ectodomain Library B

   Pooled Library

   #157972

   Purpose

   Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Bacterial and Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

9. SARS-CoV-2 Spike (S) Ectodomain Library A

   Pooled Library

   #157971

   Purpose

   Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Bacterial and Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

10. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

    Pooled Library

    #174296

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

11. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

    Pooled Library

    #174295

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

12. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

    Pooled Library

    #174294

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

13. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

    Pooled Library

    #174293

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

14. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136478

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

15. pC004 - PFS library in Beta-lactamase gene Target Plasmid

    Pooled Library

    #79153

    Purpose

    PFS library inserted at the 5' of the Beta-lactamase gene for screening PFS preference

    Depositor

    Feng Zhang

    Article

    Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

    Available since

    Oct. 26, 2017

    Availability

    Academic Institutions and Nonprofits only

16. UMI-sgRNA-TF

    Pooled Library

    #234819

    Purpose

    Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice.

    Depositor

    Benjamin Ebert

    Article

    Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    June 11, 2025

    Availability

    Academic Institutions and Nonprofits only

17. UMI-sgRNA-CH

    Pooled Library

    #234820

    Purpose

    Unique molecular identifiers-linked sgRNA library targeting chromatin factors (CH) in mice.

    Depositor

    Benjamin Ebert

    Article

    Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    June 11, 2025

    Availability

    Academic Institutions and Nonprofits only

18. Pooled sgRNA libraries Set 1 and Set 2 for Pseudomonas aeruginosa PA14

    Pooled Library

    #1000000254

    Depositor

    Xue Liu

    Available since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

19. Pooled sgRNA Libraries Set 1 for Pseudomonas aeruginosa PA14

    Pooled Library

    #234855

    Purpose

    A CRISPRi library for inducible, genome-wide gene repression in Pseudomonas aeruginosa PA14.

    Depositor

    Xue Liu

    Article

    Zhang et al bioRxiv 2024.09.01.610675

    Expression

    Bacterial

    Available since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

20. CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

    Pooled Library

    #223064

    Purpose

    Optical pooled genome-scale CRISPR KO screening using Nuclear In-Situ Sequencing (NIS-Seq)

    Depositor

    Jonathan Schmid-Burgk

    Article

    Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 23, 2025

    Availability

    Academic Institutions and Nonprofits only