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416 results

Showing: 321 - 340 of 416 results

  4. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

    Pooled library
    #174296
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  5. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

    Pooled library
    #174295
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  6. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

    Pooled library
    #174294
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  7. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

    Pooled library
    #174293
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Publication
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  10. TBG-mTSG

    Pooled library
    #113585
    Purpose
    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver
    Depositor
    Sidi Chen
    Publication
    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:
    Expression
    Mammalian
    Use
    AAV, CRISPR, Lentiviral, and Luciferase
    Available since
    July 23, 2019
    Availability
    Academic Institutions and Nonprofits only

  12. ”Brunello” hCRISPR KO - mCherry

    Pooled library
    #254661
    Purpose
    Human CRISPR knockout library with pLGR_dual_guide-Puro-mycNLS-mCherry backbone, designed using optimized metrics which combined improved on-target activity predictions (Rule Set 2), with an off-targe
    Depositor
    Laboratory for Genomics Research (LGR), Alexander Brown
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 16, 2026
    Availability
    Academic Institutions and Nonprofits only

  13. ”Brunello” hCRISPR KO – eGFP

    Pooled library
    #254660
    Purpose
    Human CRISPR knockout library with pLGR_dual_guide-Puro-mycNLS-eGFP backbone, designed using optimized metrics which combined improved on-target activity predictions (Rule Set 2), with an off-target s
    Depositor
    Laboratory for Genomics Research (LGR), Alexander Brown
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 16, 2026
    Availability
    Academic Institutions and Nonprofits only

  14. ”Brunello” hCRISPR KO – BFP

    Pooled library
    #254659
    Purpose
    Human CRISPR knockout library with pLGR_dual_guide-Puro-mycNLS-BFP backbone, designed using optimized metrics which combined improved on-target activity predictions (Rule Set 2), with an off-target sc
    Depositor
    Laboratory for Genomics Research (LGR), Alexander Brown
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 16, 2026
    Availability
    Academic Institutions and Nonprofits only

  15. hCRISPRi v3

    Pooled library
    #254658
    Purpose
    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette with a pLGR_dual_guide-Puro-mycNLS-BFP backbone.
    Depositor
    Laboratory for Genomics Research (LGR), Alexander Brown
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 16, 2026
    Availability
    Academic Institutions and Nonprofits only

  16. hCRISPRa v2

    Pooled library
    #254657
    Purpose
    Human genome-scale CRISPRa library for activation of gene transcription with a pLGR1002 backbone.
    Depositor
    Laboratory for Genomics Research (LGR), Alexander Brown
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 16, 2026
    Availability
    Academic Institutions and Nonprofits only

  17. hCRISPRi v2

    Pooled library
    #254656
    Purpose
    Human genome-scale CRISPRi library for inhibition of gene transcription with a pLGR1002 backbone.
    Depositor
    Laboratory for Genomics Research (LGR), Alexander Brown
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Oct. 16, 2026
    Availability
    Academic Institutions and Nonprofits only

  20. htCRISPRi-Puro

    Pooled library
    #254479
    Purpose
    Genome-scale CRISPRi library for inhibiting transcription of expressed genes in human T cell with 2 sgRNAs/gene; expresses puromycin resistance gene.
    Depositor
    Alexander Marson
    Publication
    Zhu et al Cell. 2026 Aug 28:S0092-8674(26)00929-3.
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    July 16, 2026
    Availability
    Academic Institutions and Nonprofits only
Showing: 321 - 340 of 416 results