388 results

1. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75312

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

2. TRE-MPRA_minCMV Library

   Pooled Library

   #201012

   Purpose

   Massively parallel reporter assay (MPRA) library with minCMV promoter

   Depositor

   Justin English

   Article

   Zahm et al Nat Commun. 2024 Nov 28;15(1):10353. doi

   Expression

   Mammalian

   Use

   Luciferase

   Available Since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis

   Pooled Library

   #101930

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

4. pMuSIC pool v1.0

   Pooled Library

   #227193

   Purpose

   Two-way barcodes from 18 fluorescent proteins for mammalian expression. Can be used for clone tracing, or for pairing with perturbations for single cell resolution in spectral detection measurements.

   Depositor

   Marc Birtwistle

   Article

   Lu et al ACS Synth Biol. 2025 May 16;14(5):1533-1

   Expression

   Mammalian

   Available Since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

5. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Gene Expression

   Pooled Library

   #1000000123

   Purpose

   CRISPR gRNA mouse knockout pooled library - Gene expression

   Depositor

   Michael Bassik

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

6. Xiaole Shirley Liu lab Human CRISPR lentiviral library

   Pooled Library

   #1000000132

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Xiaole Shirley Liu

   Available Since

   June 13, 2018

   Availability

   Academic Institutions and Nonprofits only

7. Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

   Pooled Library

   #161769

   Purpose

   Tet-inducible inhibition library targeting the yeast genome with barcode linked guide RNAs.

   Depositor

   Nicholas Ingolia

   Article

   McGlincy et al BMC Genomics. 2021 Mar 23;22(1):205. doi

   Expression

   Yeast

   Species

   Saccharomyces cerevisiae

   Use

   CRISPR

   Available Since

   Nov. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

8. mCRISPRa-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

   Pooled Library

   #84000

   Purpose

   Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available Since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

9. Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3

   Pooled Library

   #101934

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

10. BARBEKO sgRNA library

    Pooled Library

    #174163

    Purpose

    Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.

    Depositor

    Wensheng Wei

    Article

    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

11. LibTest

    Pooled Library

    #113147

    Purpose

    Customized sgRNA library targeting 86 E. coli genes

    Depositor

    Chong Zhang

    Article

    Guo et al Nucleic Acids Res. 2018 Aug 21;46(14):70

    Expression

    Bacterial

    Available Since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

12. RLC11

    Pooled Library

    #163955

    Purpose

    Targets open reading frames and non-coding RNAs in M. smegmatis.

    Depositor

    Jeremy Rock

    Article

    Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

    Expression

    Bacterial

    Use

    CRISPR

    Available Since

    Oct. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

13. DNA repair library with 1,573 sgRNAs

    Pooled Library

    #177663

    Purpose

    CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available Since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only

14. Liu Lab MusCK (A + B)

    Pooled Library

    #1000000178

    Depositor

    Xiaole Shirley Liu

    Available Since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

15. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92380

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

16. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

    Pooled Library

    #1000000096

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Eric Lander, David Sabatini

    Available Since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

17. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

    Pooled Library

    #1000000095

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Eric Lander, David Sabatini

    Available Since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

18. scQers promoter control #1 (low: minimal promoter, p027)

    Pooled Library

    #217420

    Purpose

    scQers promoter control #1 (low: minimal promoter, p027)

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available Since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only

19. hCRISPRa-v2, Gene Expression (h5), top 5 sgRNAs/gene

    Pooled Library

    #83984

    Purpose

    Human CRISPRa Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available Since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

20. lenti_LTC_v2

    Pooled Library

    #238548

    Purpose

    Lentiviral expression of the ~2000 member library of v2 lineage tracing cassettes

    Depositor

    Jonathan Weissman

    Article

    Koblan et al Science. 2025 Jul 24:eadx3800. doi: 10.1

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    Aug. 8, 2025

    Availability

    Academic Institutions and Nonprofits only