390 results

1. pSMAL-CellTag-V3

   Pooled Library

   #115645

   Purpose

   Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

   Depositor

   Samantha Morris

   Article

   Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

   Has Service

   Concentrated Lentiviral Prep

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available Since

   Dec. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

2. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Rebecca Voorhees, Jonathan Weissman

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

3. lentiCRISPRv2_ISG

   Pooled Library

   #125753

   Purpose

   Knockout library targeting a set of human interferon-stimulated genes (ISGs).

   Depositor

   Michael Emerman, Molly OhAinle

   Article

   Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   May 7, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Julianna (split-vector)

   Pooled Library

   #247028

   Purpose

   Enriched for effective guides through prioritization of guides with strong on-target activity. Designed against current gene annotations, offering coverage of the contemporary mouse genome.

   Depositor

   John Doench, David Root

   Article

   Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

5. FNLCR CRISPRa Cell Surface and FNLCR CRISPRa Soluble Libraries

   Pooled Library

   #1000000228

   Depositor

   Raj Chari

   Available Since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

   Pooled Library

   #159393

   Purpose

   Mouse lentiviral genome-wide CRISPR library

   Depositor

   Jason Moffat

   Article

   Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Nov. 9, 2020

   Availability

   Academic Institutions and Nonprofits only

7. ClonTracer Barcoding Library (2.5 ug)

   Pooled Library

   #67267

   Purpose

   High complexity 30bp-long semi random DNA barcode library in lentiviral backbone

   Depositor

   Frank Stegmeier

   Article

   Bhang et al Nat Med. 2015 Apr 13. doi: 10.1038/nm.38

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available Since

   Sept. 11, 2015

   Availability

   Academic Institutions and Nonprofits only

8. psgRNA_EcoWG1

   Pooled Library

   #131625

   Purpose

   Bacterial inhibition library targeting every small RNA and ORF of the E. coli MG1655 genome. This library has higher inhibition efficiency than the psgRNA library.

   Depositor

   David Bikard

   Article

   Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

   Expression

   Bacterial

   Species

   Escherichia coli

   Use

   CRISPR

   Available Since

   May 12, 2020

   Availability

   Academic Institutions and Nonprofits only

9. pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

   Pooled Library

   #104861

   Purpose

   Retroviral library containing gRNAs from the Yusa lab Mouse improved genome-wide library v2.

   Depositor

   Sarah Teichmann

   Article

   Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

   Available Since

   Sept. 9, 2019

   Availability

   Academic Institutions and Nonprofits only

10. Liu Mouse CRISPR Knockout Library in lentiCRISPRv2-blast

    Pooled Library

    #1000000173

    Depositor

    Xiaole Shirley Liu

    Available Since

    May 13, 2021

    Availability

    Academic Institutions and Nonprofits only

11. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75314

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

12. Pan-cancer CasRx lncRNA Albarossa library

    Pooled Library

    #212966

    Purpose

    Genome-scale library for pan-cancer interrogation of lncRNA dependencies using CasRx.

    Depositor

    Roland Rad

    Article

    Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

13. Human Lipid Droplet and Metabolism Library

    Pooled Library

    #191535

    Purpose

    Targets 1,196 genes related to lipid droplet biology and cell metabolism.

    Depositor

    James Olzmann

    Article

    Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    March 1, 2023

    Availability

    Academic Institutions and Nonprofits only

14. Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

    Pooled Library

    #171531

    Purpose

    Knockout library targeting ubiquitination and de-ubiquitination complex genes.

    Depositor

    Chunliang Li

    Article

    Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    June 22, 2021

    Availability

    Academic Institutions and Nonprofits only

15. Inzolia library in pRDA_052

    Pooled Library

    #209551

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available Since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

16. Dual sgRNA CRISPRa Library

    Pooled Library

    #1000000193

    Depositor

    Jonathan Weissman

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

17. psgRNA Library

    Pooled Library

    #115927

    Purpose

    ~93,000 gRNAs targeting random positions along the genome of E. coli MG1655 with a NGG PAM motif. Contains ~19 targets per gene and can be used with SpdCas9 to perform pooled CRISPRi screens.

    Depositor

    David Bikard

    Article

    Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available Since

    June 6, 2019

    Availability

    Academic Institutions and Nonprofits only

18. Human SLC KO Library

    Pooled Library

    #132552

    Purpose

    Knockout library targeting human SLC proteins.

    Depositor

    Giulio Superti-Furga

    Article

    Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    May 7, 2020

    Availability

    Academic Institutions and Nonprofits only

19. Mini-human AsCpf1-based human genome-wide knockout library

    Pooled Library

    #130630

    Purpose

    Knockout library targeting 16,977 genes. Each gene is targeted by an AsCpf1(AsCas12a)-based array containing 3-4 guides concatenated in one vector.

    Depositor

    Giulio Draetta

    Article

    Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 9, 2019

    Availability

    Academic Institutions and Nonprofits only

20. mCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

    Pooled Library

    #83998

    Purpose

    Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available Since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only