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Human sgRNA library Brunello in lentiCRISPRv2

Pooled Library

#73179

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
MORF Library Kit with GFP and mCherry controls

Pooled Library

#1000000218

Depositor

Feng Zhang

Available Since

March 24, 2023

Availability

Academic Institutions and Nonprofits only
Ma-PylRS-lib1

Pooled Library

#224585

Purpose

Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

Depositor

Ryan Mehl

Article

Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

Expression

Bacterial

Species

Methanomethylophilus alvus

Available Since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

Pooled Library

#1000000082

Purpose

CRISPR gRNA knockout pooled library for targeting the human kinome

Depositor

John Doench, David Root

Available Since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Perturb-seq GBC library

Pooled Library

#85968

Purpose

Barcode library for cloning gRNA sublibraries for single cell CRISPR analysis.

Depositor

Jonathan Weissman

Article

Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 14, 2017

Availability

Academic Institutions and Nonprofits only
FNLCR CRISPRa Cell Surface and FNLCR CRISPRa Soluble Libraries

Pooled Library

#1000000228

Depositor

Raj Chari

Available Since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only
Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Targets 2,981 human metabolic genes with 29,790 guide RNAs. The library contains ~10 gRNAs per gene.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available Since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

Pooled Library

#1000000048

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Feng Zhang

Available Since

May 8, 2014

Availability

Academic Institutions and Nonprofits only
Human SAM library in lentiSAMv2 backbone

Pooled Library

#1000000078

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

Feng Zhang

Available Since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Dual sgRNA CRISPRi Library

Pooled Library

#1000000192

Depositor

Jonathan Weissman

Available Since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

Pooled Library

#1000000111

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

John Doench, David Root

Available Since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only
TCR Rapid Assembly for Functional Testing (TCRAFT)

Pooled Library

#1000000264

Depositor

Michael Birnbaum

Available Since

Aug. 12, 2025

Availability

Academic Institutions and Nonprofits only
pre-associated oBC-minP-GFP-mBC backbone (p043)

Pooled Library

#194098

Purpose

pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
Toronto KnockOut version 3 library (TKOv3)

Pooled Library

#90294

Purpose

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Depositor

Jason Moffat

Article

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

Available Since

May 5, 2017

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Kinases

Pooled Library

#51044

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Human genome-wide lentiviral CRISPR gRNA library version 1

Pooled Library

#67989

Purpose

Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Depositor

Kosuke Yusa

Article

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Species

Homo sapiens, Mus musculus, and Synthetic

Use

CRISPR and Lentiviral

Available Since

Oct. 14, 2016

Availability

Academic Institutions and Nonprofits only
Watermelon

Pooled Library

#155257

Purpose

Lineage tracing library

Depositor

Joan Brugge, Aviv Regev

Article

Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

Expression

Mammalian

Use

Lentiviral

Available Since

Oct. 15, 2021

Availability

Academic Institutions and Nonprofits only
Human Lentiviral sgRNA Library - Control

Pooled Library

#51048

Purpose

Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

Depositor

Eric Lander, David Sabatini

Article

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Feb. 7, 2014

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 399 results

Results per page:

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399 results

Human sgRNA library Brunello in lentiCRISPRv2

MORF Library Kit with GFP and mCherry controls

Ma-PylRS-lib1

Human sgRNA library Brunello in lentiGuide-Puro

Human Brunello kinome pooled library, guides 1-8 in lentiGuide-Puro backbone

Perturb-seq GBC library

FNLCR CRISPRa Cell Surface and FNLCR CRISPRa Soluble Libraries

Human CRISPR Metabolic Gene Knockout Library

Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

Human SAM library in lentiSAMv2 backbone

Dual sgRNA CRISPRi Library

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

TCR Rapid Assembly for Functional Testing (TCRAFT)

pre-associated oBC-minP-GFP-mBC backbone (p043)

Toronto KnockOut version 3 library (TKOv3)

Human Lentiviral sgRNA Library - Kinases

Human genome-wide lentiviral CRISPR gRNA library version 1

Watermelon

Human Lentiviral sgRNA Library - Control

Mouse sgRNA library Brie in lentiGuide-Puro

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