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The Human Druggable CRISPR library

Pooled Library

#200013

Purpose

Knockout library containing ~10,000 sgRNAs targeting 1,980 human druggable genes (5 sgRNAs per gene and 100 non-targeting control sgRNAs).

Depositor

Lianxin Liu

Article

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
MORF Library Kit with GFP and mCherry controls

Pooled Library

#1000000218

Depositor

Feng Zhang

Available Since

March 24, 2023

Availability

Academic Institutions and Nonprofits only
Mouse GeCKO Lentiviral sgRNA Library (LentiGuide-Puro)

Pooled Library

#1000000053

Purpose

CRISPR gRNA knockout pooled library for targeting the mouse genome

Depositor

Feng Zhang

Available Since

July 23, 2014

Availability

Academic Institutions and Nonprofits only
Mouse messenger-RBP sgRNA library

Pooled Library

#169082

Purpose

Retroviral knockout library targeting mouse mRNA binding proteins with 10 sgRNAs/gene.

Depositor

Martin Turner

Article

Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Sept. 10, 2021

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib3

Pooled Library

#113136

Purpose

Genome-wide gRNA library for E. coli, sub3

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available Since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib4

Pooled Library

#113137

Purpose

Genome-wide gRNA library for E. coli, sub4

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available Since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_NC_sgRNA_lib

Pooled Library

#113146

Purpose

Genome-wide gRNA library for E. coli, non-targeting control

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available Since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Targets 2,981 human metabolic genes with 29,790 guide RNAs. The library contains ~10 gRNAs per gene.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available Since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

Pooled Library

#1000000048

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Feng Zhang

Available Since

May 8, 2014

Availability

Academic Institutions and Nonprofits only
Toronto KnockOut version 3 library (TKOv3)

Pooled Library

#90294

Purpose

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Depositor

Jason Moffat

Article

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

Available Since

May 5, 2017

Availability

Academic Institutions and Nonprofits only
Lenti-human-TF-gRNA-puromycin

Pooled Library

#162275

Purpose

Knockout library targeting a set of human transcription factors for loss-of-function screening.

Depositor

Chunliang Li

Article

Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

Species

Homo sapiens

Use

Lentiviral

Available Since

Dec. 15, 2020

Availability

Academic Institutions and Nonprofits only
lentiCRISPRv2_ISG

Pooled Library

#125753

Purpose

Knockout library targeting a set of human interferon-stimulated genes (ISGs).

Depositor

Michael Emerman, Molly OhAinle

Article

Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

May 7, 2020

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

Pooled Library

#1000000083

Purpose

CRISPR gRNA knockout pooled library for targeting the human kinome

Depositor

John Doench, David Root

Available Since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Membrane protein gRNA library

Pooled Library

#113345

Purpose

Activation library targeting the promoters of 6,213 genes that encode at least one putative membrane-associated protein isoform.

Depositor

Gavin Wright

Article

Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

Species

Homo sapiens

Use

Lentiviral

Available Since

Jan. 4, 2019

Availability

Academic Institutions and Nonprofits only
Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

Pooled Library

#1000000111

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

John Doench, David Root

Available Since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiCRISPRv2

Pooled Library

#73179

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Mouse GeCKO Lentiviral sgRNA Library (LentiCRISPR)

Pooled Library

#1000000052

Purpose

CRISPR gRNA knockout pooled library for targeting the mouse genome

Depositor

Feng Zhang

Available Since

July 23, 2014

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Mouse Metabolism Library

Pooled Library

#163966

Purpose

Knockout library targeting mouse metabolic genes.

Depositor

Alec Kimmelman

Article

Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Use

CRISPR and Lentiviral

Available Since

July 1, 2021

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 391 results

Results per page:

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More Filters

391 results

The Human Druggable CRISPR library

Human sgRNA library Brunello in lentiGuide-Puro

MORF Library Kit with GFP and mCherry controls

Mouse GeCKO Lentiviral sgRNA Library (LentiGuide-Puro)

Mouse messenger-RBP sgRNA library

E.coli_GW-sgRNA_Lib3

E.coli_GW-sgRNA_Lib4

E.coli_NC_sgRNA_lib

Human CRISPR Metabolic Gene Knockout Library

Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

Toronto KnockOut version 3 library (TKOv3)

Lenti-human-TF-gRNA-puromycin

lentiCRISPRv2_ISG

Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

Membrane protein gRNA library

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

Human sgRNA library Brunello in lentiCRISPRv2

Mouse GeCKO Lentiviral sgRNA Library (LentiCRISPR)

Mouse sgRNA library Brie in lentiGuide-Puro

Mouse Metabolism Library

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