1,187 results

Laura Drepanos from the Broad Institute shares the strategies her team used to optimize the CRISPR knockout libraries Jacquere and Julianna.

Learn about new tools in Addgene's collection, including new prime editing and CRISPR applications, tools for neuroscience research, and more!

Fourteen years after Cas9, CRISPR has moved beyond DNA cutting. Read Addgene's recap of CRISPR Frontiers 2026, covering programmable gene insertion, RNA-sensing cell killing, and next-gen base and prime editors.

Learn why Addgene requires a free login for sequence data access and how it helps protect shared research resources and community trust.

Prime editing is a search-and-replace CRISPR editing method that offers versatility and precision in genome editing. We cover common prime editing tools.

Learn about the latest statistics on CRISPR plasmid deposits and distributions and how this reflects the broader CRISPR community.

Addgene co-founder Melina Fan is transitioning to our Chief Scientific Advisor. We reflect on our history, how science has changed, and what comes next.

Learn what non-model organisms are, why scientists use them, and what they can teach us.

Learn how to navigate the PhD job market, from choosing between academia and industry to translating your skills and positioning yourself for the right role.

The REPROcode collection includes 408 barcoded lentiviral vectors carrying immune-specific transcription factors, allowing transdifferentiation screens.

High schoolers invented a new diagnostic for Lyme disease. In the process, they also created a tool for jointly designing RPA primers and Cas12a sgRNAs.

Learn about new tools in Addgene's collection, including new biosensors for neuroscience research, plasmids for a common lab enzyme, and more!

Addgene has a new brand identity! This post describes the design decisions that went into our new logo, style, introductory video, and our mascot, Blugene.

Synthetic origins of replication, or ORIs, from the Chappell Lab have improved plasmid compatibility and copy number control compared to natural ORIs.

This post, written by the creator of the CRISPRecise kit, explains how to use it to minimize off-target effects in CRISPR genome editing.

This post discusses takeaways from, and tools presented at, the Deaminet 2026 conference, focusing on base editors, prime editors, and translational work.

This post describes the development of sentinel plants, which change color to alert humans when they detect certain molecules in their environment.

Learn about hot new tools in our collection!

Learn about what's coming for Addgene in 2026

This post discusses the applications, advantages, and caveats to using hybrid guide RNAs, in which DNA bases are substituted for RNA bases.