Skip to main content

We narrowed to 6 results for: GATS

Showing: 1 - 6 of 6 results
  1. xCas9: Engineering a CRISPR Variant with PAM Flexibility

    Type
    Blog Post
    ...recognizing a broad range of PAMs like NG, GAA, and GAT, but also displaying increased editing specificity...showed the broadest PAM range, recognizing NG, NNG, GAT, and CAA PAMs, while xCas9 3.6 displayed the second...at an NGG PAM. When they tested a variety of NG, GAT, GAA, and CAA PAMs, they saw that xCas9 3.7 cleaves...efficiency), NGC (2.1-fold), NGA (1.6-fold) and GAA and GAT (5.2-fold). The low increase in NGA editing efficiency...activating transcription. Sites containing NG, GAA, or GAT PAMs averaged 56-91% transcriptional activation compared...28%). Cytidine base editing at NGT, NGC, GAA, and GAT PAMs is improved, with a smaller increase in NGA ...containing ABE7.10, as well as improvements at NG and GAT PAMs. xCas9 3.7 Activity in Mammalian Cells Construct...
  2. Components of CRISPR/Cas9

    Type
    Blog Post
    ...variant  3' NGAN or NGNG  xCas9 3' NG, GAA, or GAT SpCas9-NG 3' NG  Staphylococcus aureus (SA); ...
  3. CRISPR Guide

    Type
    Collection
    ...-NGG PAM sequences include: xCas9 — NG, GAA, and GAT; increased nuclease fidelity SpCas9-NG — NG; increased...VQR variant 3' NGAN or NGNG xCas9 3' NG, GAA, or GAT SpCas9-NG 3' NG Staphylococcus aureus (SA); SaCas9...
  4. CRISPR Guide

    Type
    Guide
    ...-NGG PAM sequences include: xCas9 — NG, GAA, and GAT; increased nuclease fidelity SpCas9-NG — NG; increased...VQR variant 3' NGAN or NGNG xCas9 3' NG, GAA, or GAT SpCas9-NG 3' NG Staphylococcus aureus (SA); SaCas9...
Showing: 1 - 6 of 6 results