We narrowed to 359 results for: Nov
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TypeBlog Post...choice. ThermoFischers GeneArt Gene Synthesis NovoPro Labs Codon Optimization Tool (ExoOptimizer) Genewiz...Addgene;s dataset reveals trends in biological innovation Resources on Addgene.org Check out Addgene'...
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Important Considerations in Optogenetics Behavioral Experiments
TypeBlog Post...neurons are activated when the mouse is placed in a novel context. As a proof-of-principle test, the authors...show that HR blocked neuronal activation in the novel context as determined by reduced c-fos expression... -
SARS-CoV-2/COVID-19 Detection Methods Based on CRISPR/Cas
TypeBlog Post...19 testing methods. Rapid detection of 2019 novel coronavirus SARS-CoV-2 using a CRISPR based DETECTR...for rapid, ultrasensitive and visual detection of novel coronavirus SARS-CoV-2 Sensitivity: 4.6-11 copies... -
New Optogenetic Tools for Cytoskeleton and Membrane Control
TypeBlog Post...are not easily reversible. Late last year, the Akhmanova Lab published a new optogenetic tool for localized...Grigoriev, I., Nijenhuis, W., Kapitein, L. C., & Akhmanova, A. (2022). Opto-katanin, an optogenetic tool ... -
Viral Vectors 101: Integrase-Deficient Lentiviral Vectors
TypeBlog Post...adeno-associated virus, herpesviruses, hepatitis B virus, adenoviruses, and human papillomavirus (HPV), to name a few...though the rate of loss greatly depends on cell turnover. Why use integrase-deficient lentiviral vectors... -
The Fluorescent Vegetables in Aptamer Soup
TypeBlog Post...capable of inducing the brightest fluorescence (Filonov et al., 2014). Broccoli is twice as bright as Spinach2...9.10 (2014): 2412-2420. PubMed PMID: 25101481. Filonov, Grigory S., et al. "Broccoli: rapid selection ... -
Fluorescent Proteins 101: When GFP lets you down
TypeBlog Post...e.g. mScarlet) or infrared fluorescent proteins (Chernov et al., 2017) may improve detection. Since longer...24360272. PubMed Central PMCID: PMC3918502. 14. Chernov, Konstantin G., et al. "Near-infrared fluorescent... -
Evolution of Lab Techniques
TypeBlog Post...papers or are brainstorming new technological innovations. Let’s take a look at three historical techniques...past. In the sequencing world, one up and coming innovation is nanopore-based DNA sequencing which reads ... -
Hot Plasmids: Spring 2025
TypeBlog Post...flexibility and speed, so you can design, test, and innovate faster than ever. Plus, we've already taken them...potential. Our partners at the Institute for Protein Innovation (IPI) recently released a set of highly-specific... -
Viral Vectors 101: AAV Serotypes and Tissue Tropism
TypeBlog Post...-023-39554-7 Issa, S. S., Shaimardanova, A. A., Solovyeva, V. V., & Rizvanov, A. A. (2023). Various AAV... -
Building Global Connections with the International Mentorship Program USA-EUROPE
TypeBlog Post... can exchange ideas, network, collaborate, and innovate internationally. Why an International Mentorship...Spanish Secretary of Research, Development, and Innovation, D. Carmen Vela, who reiterated the Spanish government... -
27 Hot Plasmids from 2016
TypeBlog Post...strategies for combating cancers. To facilitate innovative cancer research, the Reference Reagents Group...robust CRISPR activators We previously reported on a novel Cas9-based activator developed by the Church lab...-X identified both previously characterized and novel mutants. Hess et al. envision CRISPR-X as not only... -
Live and Let Dye: Self-Labeling Protein Tags
TypeBlog Post...substrate-linked PEG, biotin, or magnetic beads. In one innovative example, the Zhang lab used SNAP-tag to decorate...Bulleit, R. F., & Wood, K. V. (2008). HaloTag: A Novel Protein Labeling Technology for Cell Imaging and... -
An “elegans” Approach to Better CRISPR/Cas9 Editing Efficiency
TypeBlog Post...simplifies design of these constructs, allowing novice researchers to quickly and easily start genome ...technology into C. elegans has been a transformative innovation for our community. Developments in mammalian ... -
Typing CRISPR Systems
TypeBlog Post...V., Fedorova, I., Karneyeva, K. A., Artamonova, D. N., & Severinov, K. V. (2021). Type III CRISPR-CAS ... -
Fluorescent Proteins 101: Monitoring Cell Mobility Using Fluorescent Proteins
TypeBlog Post...sites of infection or damage (Peters et al. 2008, Chtanova et al. 2008, Kamenyeva et al. 2015)? How do blood...18703742. PubMed Central PMCID: PMC2606057. 2. Chtanova, Tatyana, et al. "Dynamics of neutrophil migration... -
Antibody Guide
TypeCollection...sdAb. sdAbs can have weak signals due to their monovalent nature. Darpins - Darpins are genetically engineered... -
Advice on Career Paths and the Green Card Process for International Researchers and Entrepreneurs
TypeBlog Post...example, you were the first person to identify a novel protein found in skin cancer and your continued ...career development firm focused on connecting innovative, entrepreneurial companies with like-minded professionals... -
Viral Vectors 101: Systemic Capsids
TypeBlog Post...Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. PloS One...Sabeti, P. C. (2023). Systemic administration of novel engineered AAV capsids facilitates enhanced transgene... -
Beginner's Guide to Viral Vectors
TypeBlog Post...characteristics of retroviruses, lentiviruses, AAVs, and adenoviruses in this easy-to-use guide. Print out the guide...