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  1. SARS-CoV-2/COVID-19 Detection Methods Based on CRISPR/Cas

    Type
    Blog Post
    ...19 testing methods.   Rapid detection of 2019 novel coronavirus SARS-CoV-2 using a CRISPR based DETECTR...for rapid, ultrasensitive and visual detection of novel coronavirus SARS-CoV-2 Sensitivity: 4.6-11 copies...
  2. New Optogenetic Tools for Cytoskeleton and Membrane Control

    Type
    Blog Post
    ...are not easily reversible. Late last year, the Akhmanova Lab published a new optogenetic tool for localized...Grigoriev, I., Nijenhuis, W., Kapitein, L. C., & Akhmanova, A. (2022). Opto-katanin, an optogenetic tool ...
  3. Fluorescent Proteins 101: When GFP lets you down

    Type
    Blog Post
    ...e.g. mScarlet) or infrared fluorescent proteins (Chernov et al., 2017) may improve detection. Since longer...24360272. PubMed Central PMCID: PMC3918502.  14. Chernov, Konstantin G., et al. "Near-infrared fluorescent...
  4. Evolution of Lab Techniques

    Type
    Blog Post
    ...papers or are brainstorming new technological innovations. Let’s take a look at three historical techniques...past. In the sequencing world, one up and coming innovation is nanopore-based DNA sequencing which reads ...
  5. Arf GTPase Family

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    Collection
    ...GAPs: concepts and challenges Sztul E, Chen PW, Casanova JE, Cherfils J, Dacks JB, Lambright DG, Lee FS...
  6. 27 Hot Plasmids from 2016

    Type
    Blog Post
    ...strategies for combating cancers. To facilitate innovative cancer research, the Reference Reagents Group...robust CRISPR activators We previously reported on a novel Cas9-based activator developed by the Church lab...-X identified both previously characterized and novel mutants. Hess et al. envision CRISPR-X as not only...
  7. Mammalian RNAi Tools

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    Collection
    ...Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD. RNA. 2003. 9(4):493-501. PubMed ....
  8. Plant Plasmids and Resources

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    Collection
    ... exchange, open technologies, and responsible innovation for improvement of sustainable agriculture and...
  9. Live and Let Dye: Self-Labeling Protein Tags

    Type
    Blog Post
    ...substrate-linked PEG, biotin, or magnetic beads. In one innovative example, the Zhang lab used SNAP-tag to decorate...Bulleit, R. F., & Wood, K. V. (2008). HaloTag: A Novel Protein Labeling Technology for Cell Imaging and...
  10. Typing CRISPR Systems

    Type
    Blog Post
    ...V., Fedorova, I., Karneyeva, K. A., Artamonova, D. N., & Severinov, K. V. (2021). Type III CRISPR-CAS ...
  11. Viral Production

    Type
    Collection
    ...serotype-specific Cap genes, and a plasmid encoding adenoviral helper sequences. AAV preparations are purified...
  12. Plan Your Experiment

    Type
    Collection
    ...DSBs): For small nucleotide edits that introduce a novel restriction site. The region of interest is PCR ...
  13. The Pleiades Promoter Project

    Type
    Collection
    ...Hearty TG, Imanian B, Jiang S, Khorasan-zadeh S, Komljenovic I, Laprise S, Liao NY, Lim JS, Lithwick S, Liu...
  14. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    ...Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids. PloS One...Sabeti, P. C. (2023). Systemic administration of novel engineered AAV capsids facilitates enhanced transgene...
Showing: 181 - 200 of 357 results