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Find materials useful for neurodegeneration research.

A selection of Addgene's empty vector backbones curated by species, epitope tags/fusion proteins, function, selectable markers, and more.

Drive-and-proccess (DAP) arrays are a new tool from the Gao lab that allows for up to 31-loci CRISPR multiple base editing.

CRISPR/Cas9 systems have been shown to mediate gene correction in mice and in human stem cells demonstrating the therapeutic potential of CRISPR technology.

Learn more about Addgene's NGS verification process for pooled libraries using real-life amplication data from the Brunello gRNA library.

We describe the different modular cloning kits available for different applications and organisms to help you find the kit that's right for your experiment.

Explore empty plasmid backbones with different fluorescent tags to create fusion proteins with your gene of interest.

How much time does it take to clone a plasmid and how much does it cost? We do some back of the envelope math to try and figure it out!

Our February hot plasmids, including two new CRISPR tools, a protein ladder, and anti-FLAG frankenbodies.

This post discusses takeaways from, and tools presented at, the Deaminet 2026 conference, focusing on base editors, prime editors, and translational work.

22 of the interesting and popular hot plasmid technologies of 2014 from Addgene's plasmid repository.

Check out all of the plasmids featured in our hot plasmids articles from 2016.

Comparing and contrasting Cas9 to the other genome editing-capable Cas family proteins.

GPCRs are receptors that respond to stimuli and elicit cellular responses. Learn about the parts of GPCRs, how they work, and tools to study them.

CRISPR plasmids based on Cas13 designed to precisely edit RNA targets.

Browse depositor collections of antibody, CRISPR, disease research, visualization, protein expression, synthetic biology, and viral vector plasmids.

Gamma-retroviral vectors and lentiviral vectors can be used in a wide variety of experiments including those involving genome engineering, RNAi, and inducible gene expression. In this post, learn about some of the most popular viral vectors available from Addgene and their uses.

This post provides an overview on how transcription terminates in prokaryotes and eukaryotes.

Where did plasmids come from? Learn more about natural plasmids, the benefits they offer cells, and how scientists have adapted them into laboratory tools.

Find the basics about chemogenetics: what are chemogenetics, why use them, and how to build your chemogenetic system using receptors and ligands.