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We narrowed to 970 results for: Abo;

Showing: 221 - 240 of 970 results

  1. xCas9: Engineering a CRISPR Variant with PAM Flexibility

    Type
    Blog Post
    ...Blog Learn about Engineered Cas9 PAM Variants Read about CRISPR Base Editing Learn about Homology Directed...editing specificity. We’re excited to learn more about xCas9 - here’s what we know so far! Why do we ...point mutations, also has a strict editing window about 15 nt upstream of the PAM. Even if there’s a PAM...in mammalian cells, finding xCas9 3.7 displayed about the same editing rate as SpCas9 at an NGG PAM. When...are exciting, there’s a lot we still don’t know about xCas9. “I’m not 100% sure xCas9 is going to be flat...Find CRISPR Plasmids for Mammalian Systems Learn about CRISPR History ...

  2. Transferable Skills: Negotiation

    Type
    Blog Post
    ...negotiate with friends, partners, and/or children about everything from what you’re going to eat for dinner...Negotiation as a zero sum game Some people think about negotiation as a zero sum game - that is, if I get... three examples depend on many specific details about the individuals, each example provides a scenario... difficult because of the need to be thoughtful about what is most important to each person. It can especially...of us associate with negotiating (check out more about conflict resolution). How to develop negotiation...before, during, or after a negotiation to think about the situation, your reaction, and the outcome. How... able to take my vacation? I want to learn more about a different area of the company. How can I negotiate...

  3. Editor's Choice, October 2016

    Type
    Blog Post
    ...record readership with over 75,000 views. Changing Labor Laws Bring Increased Postdoc Wages Our most popular... for anyone considering a postdoc. In “Changing Labor Laws Bring Increased Postdoc Wages,” Future of Research...thorough yet concise rundown of how recently enacted labor laws will likely increase postdoc earnings in the...changes quickly and harmlessly. Learn much more about the laws and their possible repercussions in Gary...This post leads readers to our latest podcast all about graduate student life and how establishing a thriving...to Use Reddit for Science Communication Changing Labor Laws Bring Increased Postdoc Wages I hope you all... labor laws...

  4. SciComm: Taking Science to Elementary and Middle Schools

    Type
    Blog Post
    ...wonderful tangents. Some groups asked about vaccines, others were curious about the agricultural repercussions...roles and responsibilities, I have to think a lot about how to balance those roles. I’m a father of three...community. This past year, I spent some time thinking about how I could combine all of these roles by reaching...guest presentations. If you’re a scientist thinking about reaching out to your community’s schools, here are...accountants running our math tables!  Be realistic about what you can teach  5-10 year olds in a single evening...DNA, protein, plasmid, gene, etc. Though I talked about CRISPR’s molecular mechanism, I was careful to keep... I gave my presentation five times to groups of about 50 students each, and each group went on its own...

  5. A Guide to Starting Your Own Journal Club

    Type
    Blog Post
    ...think about. Choosing a topic and gauging interest The first thing to do if you’ve thought about starting... discussions. Beyond the excitement of learning about new cutting edge science, researchers of all varieties...help stay current on new and emerging work by collaboratively discussing recent publications in a specific...up. At Addgene, we wanted to think more closely about the wealth of high-throughput sequencing (HTS) data...the paper.  Before the first journal club, think about the meeting itself A journal club should aim to ...published science. They also serve as a way to learn about work outside of one's own field in a structured ...hope that with some of the information described above you feel empowered to start your own journal club...

  6. Advancing Biology with Zebrafish: Genetic Tools for Developmental Studies and More

    Type
    Blog Post
    ...for gene manipulation together with information about the genome are powerful resources for investigating...zebrafish genome was published in 2013, revealing that about 70% of human genes have a counterpart in zebrafish...networks that regulate processes from development to metabolism to fertility. Several zebrafish-specific gene...gene expression databases that provide information about when and where genes are active in developing embryos...genome sequences become available, new hypotheses about specific genetic interactions arise and tools to...genome, their long three-month generation time and labor-intensive maintenance compared to invertebrate model...Patrick Müller’s group at the FriedrichMiescher Laboratory of the Max Planck Society in Tübingen, Germany...

  7. Science Communication for Everyone

    Type
    Blog Post
    ...created The Addictive Brain to spread awareness about how scientists utilize tax-payer money and government...Here, Sadangi and his team answer a few questions about The Addictive Brain and science communication for...science communication? At The Addictive Brain, we collaborate with scientists from around the world and help...numerous feedbacks from our non-scientist readers about how our articles have helped them understand different...at The Addictive Brain? This year, we plan to collaborate more with physicists, chemists, and mathematicians...having to extensively use Google search. Be careful about hidden connotations behind a word. Non-scientists...Sign up to receive our science career guide Learn about different careers in science communication Resources...

  8. SciComm with the Experts at Science in the News Part 2

    Type
    Blog Post
    ...To learn more about the STIN's podcast, email [email protected]    For more info about starting your...evens where scientists can grab a beer and chat about their work at a local bar. It doesn't have to be...1: Introduction - Vini and Amy tell us a little about themselves. Chapter 2: What is Science in the News...science communicators. In this chapter we learn about some of their events - science seminars, science...the lab and working with SITN. She points to collaboration and delegating as keys achieving success. Chapter...your own SciComm organization and to learn about some of SITN's other initiatives, email [email protected]...

  9. The CRISPR Software Matchmaker: A New Tool for Choosing the Best CRISPR Software for Your Needs

    Type
    Blog Post
    ...databases mentioned above or, even better, first-hand knowledge from laboratories employing CRISPR on ... CRISPR system was involved. Today, that same laboratory enjoys a successful edit rate of over 90% in ...targetable NGG PAM sites whereas the human genome has about 300 million. With such a sparsely targetable genome...worse by an ever increasing marketplace. Since 2013 about 11 tools have been added every year.   Breaking ...databases are still young and will require a collaborative effort from the community in order to succeed...screen shot and overview of the table can be found above). These categories are further discussed below (.... For this reason I generally recommend that laboratories that have already attempted several CRISPR experiments...

  10. Scientific Sharing in the Time of COVID-19: Databases and Resources

    Type
    Blog Post
    ...blog Read about COVID-19 research on the blog Visit our guide for external collaborations Resources ...scientific sharing. Already we’ve seen articles about COVID-19 on preprint servers and in journals, and...vary, everyone we spoke with sees sharing and collaboration as the best way that the scientific community...useful resources during this time. Facilitate collaborations within the scientific community The team behind... Canada is a database that provides information about reagents, funding and volunteer opportunities, protocols...CCRP2) at Rutgers University not only supports collaborations at Rutgers, but also lists data and experimental...

  11. 9 Tips to Achieve Success in Academia

    Type
    Blog Post
    ... passionate about. Check out my previous post if you're looking for more information about the benefits...every spurious result under the sun. Academia is about convincing results, and nothing is more convincing...is your passion? Even if no one else is excited about it, distinguish yourself with this passion. “Love...presentations and of course, networking and collaborating.” Getting out of the lab also “opens the student's...emphasizes the importance of passion, hard work, collaboration, and staying honest with personal goals. Stay...George Church for answering our burning questions about how they manage and motivate their labs! Update...

  12. Replacing Paper: Tips for Choosing an Electronic lab Notebook

    Type
    Blog Post
    ...allow you to collaborate within the platform and avoid countless emails. Important collaborative functionalities...of the software. We identified that when talking about ELN costs and limited budgets, “a large percentage...Besides that, academic institutions tend to think about the long term, so they need a solution for which...institution. In the study, respondents were also asked about how important ease of use is for them (if they are...or partners to access your data? If you are collaborating with other labs or clients, you might need share...comments, added files, notes etc. Detailed records about every action performed in the lab (user, date, time...Additional Resources on the Addgene Blog Learn about more tools for reproducibility 5 great apps for ...

  13. Transferable Skills Guide: Conflict Resolution

    Type
    Blog Post
    ...rely on what I know about those particular teams at that given time. I think about how previous iterations...disagreements. In fact, conflict resolution isn’t just about resolving conflicts between other people, but resolving...normally get along well with each other disagree about a specific decision, direction, or goal. Resolving...of lapsed communication. Making some assumptions about how something should be communicated is necessary...confusion around... Ownership: Misunderstandings about who is responsible for what tasks or projects is...conflicts.  Transitioning a conflict into a collaboration may not be the easiest resolution to accomplish...cooperation: avoiding, competing, accommodating, collaborating, and compromising. Though there may be a time...

  14. Oh, The Places You Can Go: Careers in Science Communication - Product Development

    Type
    Blog Post
    ...Science Communication blog series, you’ll learn about Caitlin Runne-Janczy, a Product Development Manager...G-proteins at the time. This program takes what you know about it [your area of research], and teaches you how ... hustle on the side. “I actually stumbled upon, about 6 months in, this opportunity to do scientific editing....” But Caitlin’s persistence paid off: “I spent about 6 months just editing and searching for a job and...Additional Resources on the Addgene Blog Learn more about alternative science careers here Be like Caitlin...just for good measure, here’s a few other posts about developing transferable skills while in grad school...school Resources on Addgene.org Learn more about careers at Addgene ...

  15. Walking beside Academia and giving it a high five: My transition from graduate work to a position at Addgene

    Type
    Blog Post
    ...end up in academic positions (I’ve even blogged about this here and here); however, simply put, I moved...better and because I really like talking to people about and communicating science. The path to science communication...realized that I’m energized by talking to people about science and that I love explaining things to people...I spent a couple of days talking to researchers about their work, picking up plasmid deposits, and trying...glad I did a PhD and even more glad that I thought about careers outside of academia during my graduate training...to many different fields. If you start thinking about preparing yourself for a career while still in graduate...Careers Posts Visit the Addgene Careers Page Learn about Management for Scienitsts from Addgene Executive...

  16. Addgene Receives NIH BRAIN Initiative Grant to Create Open-Access Recombinant Antibody Resource

    Type
    Blog Post
    ... You can learn more about recombinant antibodies in this blog post. Hello, NABOR! Addgene will bring ... resource for the neuroscience community called NABOR (Neuroscience AntiBody Open Resource). We are delighted... validating these tools. While the focus of the NABOR platform will be neuroscience reagents and data,...Bourges, Addgene’s interim Executive Director. “NABOR provides a new model for the creation and acquisition... the NIH’s BRAIN Initiative has been funding laboratories, such as Dr. Trimmer’s lab, to create recombinant...Check out our Antibodies 101 blog post Learn more about plasmid-based recombinant monoclonal antibodies ...

  17. "Build Your Plasmid": The Game - Play to Teach

    Type
    Blog Post
    ...manipulation more hands on While teaching courses about gene therapy and genetic manipulation, I and other...with some other professors, I went home thinking about how to solve this problem. I didn’t want to face...therapeutic strategies work. Find Addgene Blog posts about other educational tools Playing BUILD YOUR PLASMID...winner? Ultimately, society should be! This is a collaborative game, as it should be in real scientific practice...practice transferable skills like team building, collaborative critical thinking, and communication among others.... My impression was that they had clearer ideas about gene therapy in the following lessons. And let me...biology Learn how BioBuilder can help teach students about Synthetic Biology Find Arabidopsis educational resources...

  18. FPbase: A new community-editable fluorescent protein database

    Type
    Blog Post
    ...collate some of the current “best” FPs, and I collaborated with him on a web-based interactive visualization...deal more information that one might like to store about FPs than is currently represented at fpvis (complete...thousands of scientists routinely using and thinking about FPs, it would be great to have a centralized, community-editable...resource for storage and dissemination of information about FPs. FPbase.org FPbase is a project written in ...comprehensive community resource for information about fluorescent proteins.  It was designed with the ... there is plenty of room for improvement and elaboration.  Current projects include incorporation of biosensors...protein evolution lineages, 2-photon spectra, more elaborate spectrum analysis tools, and a better way to store...

  19. How to Lead a Great Meeting

    Type
    Blog Post
    ...each of your meeting types (see above). We’ve provided some tips above for what works well at Addgene,...opposite effect. A great meeting should produce collaboration - a sense of dialogue and community among participants...meeting to discuss something difficult, be excited about the prospect of working toward a solution. At the...sections for each person to add a bullet or two about what they are working on. Building this into the...purpose of the meeting (see “defining the scope” above) or if you can cut it down to thirty minutes. ...some tips. Before long, you will be running collaborative, informative, energizing meetings all your own...

  20. Advice for Scientists Starting a Lab

    Type
    Blog Post
    ...start their own academic research laboratory. How does one even go about starting a lab? Obviously, funding...always helps. But how does one build a strong collaborative research team motivated by similar visions and...booklet. What has been the most surprising thing about becoming a PI? Tom Ellis has a one word answer: ... has to deal with. My inbox currently stands at about 65,000 messages and dealing with email can be half...the first couple of hires to build a strong, collaborative team. And take advantage of the many resources...Medical School) for taking the time to speak with us about adding new scientists to their labs. Further Reading...
Showing: 221 - 240 of 970 results