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We narrowed to 545 results for: val

Showing: 221 - 240 of 545 results
  1. A Better Way to Get Customer Support: The Help Center

    Type
    Blog Post
    ...Addgene, we certainly hope not! One of our core values here is to provide unmatched customer support, ...improving the support we provide based on your valuable feedback. This is Addgene after all, and making...
  2. Mapping the 4D nucleome with CRISPR/Cas9

    Type
    Blog Post
    ...targets ~2 Mbp apart, they noticed that they could evaluate the degree of chromatin compaction even for this...imaging. Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. Cell. 2014 Oct 23;159(3):635-46. doi: 10.1016...
  3. Future of Research Conference - Remarkable Opening Session

    Type
    Blog Post
    ...is unsustainable, hypercompetition is corroding values, we are shifting away from PI driven basic research...science careers. She advocated for increasing the value and priority put on good mentoring and applauded...
  4. CASTing Off for New Shores in Human Genome Editing

    Type
    Blog Post
    ...transposons open whole new worlds to explore. The newest arrival on the scene is called evoCAST — an evolved CRISPR-associated...individualized optimizations, safety testing, and approval. In contrast, a system that can deliver a healthy...
  5. Cellosaurus: A Cell Line Information Database

    Type
    Blog Post
    ...reproducibility of scientific data depends on validated reagents along with clear documentation, so we...programatically, their API allows fine grained query and retrieval of all the information in the resource.  This ...
  6. Sleeping Beauty Awakens for Genome Engineering

    Type
    Blog Post
    ...). The original plasmid is empty following the removal of the transposon; the plasmid is then degraded...chimeric antigen receptor (CAR) therapy. SB is a valuable tool and an alternative to CRISPRs for genome ...
  7. Advice for Choosing a Research Project

    Type
    Blog Post
    ...especially you!) care about. Have you critically evaluated your plan? Have you read the relevant literature... doing the same experiment for too long. Keep evaluating your project along the way. Advice from principal...
  8. Addgene Begins Distribution of Recombinant Antibodies

    Type
    Blog Post
    ...educational materials, protocols, and shared data, on our values of transparency, reproducibility, and community-building... use in brain imaging (Andrews et al., 2019), validated in both western blot and immunohistochemistry....
  9. Hot Plasmids and Viral Preps - September 2021

    Type
    Blog Post
    ...robust expression of high G+C content genes, as validated through monitoring the expression of fluorescent...sensors New AAV tools to selectively control parvalbumin interneurons from the Dimidschstein Lab More ...
  10. Summer SciComm: Science Storytelling

    Type
    Blog Post
    ... the outcome of the project, or illustrates the value of the work and then build a story around them. ...way at the bottom of my story” and that’s a very valid critique! But do you remember earlier when I said...
  11. Behind the Scenes of Addgene’s New Look

    Type
    Blog Post
    ...scientifically rigorous and warm and human. Our values haven't changed, even as we have grown. Visually...the years, we recognized that what we offer — validated tools, streamlined sharing processes — is relevant...
  12. Antibodies 101: Epitope Tags

    Type
    Blog Post
    ...Myc was developed in 1985 and is still the most prevalent clone used today! Goat, chicken, mouse, or rabbit... brought about by the tag so it’s important to validate tagged protein functionality (Arribere, et al)...
  13. Comparing Cas9 to NgAgo: Can the Argonautes Best CRISPR?

    Type
    Blog Post
    ...small capacity viral vectors such as AAV. Base removal RNA-guided CRISPR enzymes cause double-stranded...a natural context, it’s hypothesized that base removal helps prevent the invading genome from “recovering...
Showing: 221 - 240 of 545 results